• <table id="gigg0"></table>
  • west china medical publishers
    Author
    • Title
    • Author
    • Keyword
    • Abstract
    Advance search
    Advance search

    Search

    find Author "沈宏" 6 results
    • 亞甲基四氫葉酸還原酶基因C677T和A1298C位點多態性與胃癌易感性的相關性分析

      目的探討亞甲基四氫葉酸還原酶(MTHFR)基因C677T和A1298C位點多態性與胃癌易感性的相關性。 方法回顧性收集2008年1月至2014年1月期間在筆者所在醫院住院的、行MTHFR基因C677T和A1298C位點檢測的160例胃癌患者作為胃癌組,收集同期160名自愿接受上述基因檢測的健康體檢人員作為對照組,比較2組2種位點基因型的分布情況。 結果胃癌組患者MTHFR基因C677T位點的基因型為:CC 72例,CT 64例,TT 24例;對照組為:CC 78例,CT 69例,TT 13例。胃癌組患者MTHFR基因A1298C位點的基因型為:AA 58例,AC 84例,CC 18例;對照組為:AA 62例,AC 77例,CC 21例。2組C677T位點及A1298C位點的基因型分布比較差異均無統計學意義(P>0.05)。 結論MTHFR基因C677T位點和A1298C位點多態性與胃癌的易感性無明顯相關性。

      Release date: Export PDF Favorites Scan
    • Short-Term Clinical Effect of Composite Digestive Enzyme Capsule in Treatment of Digestive Hypofunction after Cholecystectomy

      目的 探討復合消化酶膠囊治療膽囊切除術后消化功能減退癥的臨床療效。方法 將84例膽囊切除術后出現消化功能減退的患者按住院日單雙號原則分為對照組(n=41),給予抑酸藥奧美拉唑腸溶膠囊與促胃腸道動力藥多潘立酮片;觀察組(n=43)加用復合消化酶膠囊。比較2組患者的臨床療效。結果 觀察組顯效14例,有效21例,好轉7例,無效1例,總有效率為97.7%(42/43);對照組顯效10例,有效15例,好轉10例,無效6例,總有效率為85.4%(35/41)。觀察組的臨床療效較優(P<0.05)。用藥過程中均未發生不良反應。結論 復合消化酶膠囊對膽囊切除術后因膽汁分泌障礙而引起的消化功能減退癥具有確切療效。

      Release date:2016-09-08 10:34 Export PDF Favorites Scan
    • Clinical Effect of Gastric Bypass Surgery in Treatment for Patients with Type 2 Diabetes and Its Related Effect Factors

      目的探討胃轉流術治療2型糖尿病的療效及分析影響療效的相關因素。 方法回顧性分析2009年1月至2012年7月期間我院收治的33例行胃轉流術治療的2型糖尿病患者的臨床資料及隨訪情況。 結果33例患者治愈率為54.55%(18/33),總有效率為90.91%(30/33),無效3例。分析治愈及未治愈患者術前的臨床資料發現,與未治愈患者比較,治愈患者的年齡更小、病程更短、2 h BG更低、BMI更大及空腹C肽更高(P<0.05)。 結論從本組有限資料的初步結果看,胃轉流術治療2型糖尿病臨床效果確切,而對于低齡、病程短、BMI及空腹C肽較高和2 h BG較低的2型糖尿病患者可獲得更好的治療效果。

      Release date: Export PDF Favorites Scan
    • Clinical Study of Laparoscope Combined with Choledochoscope in Treatment of Patients with Cholecystolithiasis and Choledocholithiasis

      Objective To study the clinical effects of laparoscope combined with choledochoscope in patients with cholecystolithiasis and choledocholithiasis. Methods Clinical data of 74 patients with cholecystolithiasis and choledocholithiasis between Mar. 2009 and Feb. 2011 in our hospital were retrospectively analyzed. Among them, 37 cases underwent the laparoscope combined with choledochoscope operation (referred to as the double mirror operation group) and 37 cases underwent the conventional open operation (open operation group). The intraoperative conditions, therapeutic effect, and complications of patients in 2 groups were compared. Results The stone clearance rates of the two groups were 100%. The recurrence rate of 2 groups in the follow-up process was no significantly difference (P>0.05). In the double mirror operation group, the operative time was significantly longer than that open operation group (P<0.01);the intraoperative bleeding was significantly less than that open operation group (P<0.01);the anal exhaust time after operation, get out of bed time after operation, and total duration of hospitalization were significantly shorter than that open operation group (P<0.01);and the incidence of postoperative complications was significantly lower than that open oper-ation group(P<0.01). Conclusion Laparoscope combined with choledochoscope in treatment of cholecystolithiasis and choledocholithiasis patients has exact effects, with minor trauma, quicker recovery, and fewer complications, and it’s worthy of promotion.

      Release date:2016-09-08 10:35 Export PDF Favorites Scan
    • Analysis of Association Between The Polymorphisms of DNA Repair Gene XRCC1 and Susceptibility to Colorectal Cancer

      目的探討DNA損傷修復基因XRCC1 Arg194Trp位點多態性與結直腸癌易感性的關系。 方法選取120例結直腸癌患者與120例正常對照者進行對比研究。取外周血提取DNA,采用限制性片段長度多態性聚合酶鏈反應(PCR-RFLP)技術對XRCC1 Arg194Trp基因多態性進行檢測分析,比較不同基因型與結直腸癌易感性的關系。 結果2組觀察對象在年齡、性別、吸煙、飲酒、飲食特點等常見暴露因素方面的差異均無統計學意義(P>0.05),變異基因型Arg/Trp+Trp/Trp出現頻率在2組觀察對象中分別為30.00%和24.17%,差異無統計學意義(P>0.05)。 結論XRCC1 Arg194Trp位點多態性與結直腸癌的易感性并無顯著相關性。

      Release date: Export PDF Favorites Scan
    • Atypical Adrenal Phaeochromocytoma: A Retrospective Clinical Study

      Objective To retrospectively analyze the clinical information of a series of patients with atypical adrenal phaeochromocytoma in order to improve the diagnosis of atypical phaeochromocytoma. Methods Ninety patients diagnosed pathologically as adrenal phaeochromocytoma from January 1998 to December 2004 in the Affiliated Hospital of Inner Mongolia Medical College were included in the study. Patients with phaeochromocytoma were classified into the typical group and atypical group based on their clinical manifestations. The differences were analyzed between the two groups in terms of patient age, tumor location and maximal diameter, incidence of hypertension, and plasma catecholamine level. Results About 24.4% (22/90) of the patients with phaeochromocytoma were classified as atypical. There was no significant difference in the maximal tumor diameter between the two groups. The plasma norepinephrine level of the atypical group was significantly lower than that of the typical group (P=0.001), and the positive rate of plasma norepinephrine of the atypical group was also lower than that of the typical group (P=0.003). Conclusion  Compared with typical phaeochromocytoma, atypical phaeochromocytoma is associated with a lower plasma norepinephrine level. The size of adrenal tumor cannot contribute to the diagnosis of atypical phaeochromocytoma. Based on atypical manifestations, CT examination results, and plasma catecholamine level, most atypical phaeochromocytoma should be diagnosed correctly.

      Release date:2016-08-25 03:36 Export PDF Favorites Scan
    1 pages Previous 1 Next

    Format

    Content

  • <table id="gigg0"></table>
  • 松坂南