There is an increase in published studies relevant to the development of patient version of guidelines (PVGs). We reviewed, summarised and analysed the current developments in this field, with the aim of informing domestic scholars of the factors to consider when developing quality PVGs. We proposed three recommendations: (1) the concept of patient guidelines needs to be better defined; (2) a platform for the dissemination of PVGs should be established to support their implementation; and (3) a standardised PVGs development methodology should be developed to ensure the quality of the PVGs.
In recent years, the application of large language models (LLM) in medical research has rapidly expanded, covering a wide range of critical areas such as clinical question-answering, diagnostic assistance, and medical record generation. However, conducting such research not only requires adherence to the fundamental principles of traditional clinical epidemiology but also must meet the unique methodological demands of artificial intelligence technologies. To this end, this article systematically summarizes key aspects of LLM-based medical research, including study design, measurement metrics, methodological quality assessment, and reporting standards, aiming to provide methodological support for medical researchers and facilitate the more standardized and efficient application of LLM technology in medical practice and scientific innovation.