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    find Author "LIU Zengrong" 2 results
    • Correlation between Serum Lipid Metabolism and Coronary Artery Pathology in Children with Kawasaki Disease

      目的 探討川崎病(Kawasaki disease,KD)患兒血脂代謝與冠狀動脈病變之間的關系。 方法 納入2007年1月-2009年10月住院治療的82例KD患兒,檢測治療前后血總膽固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)、極低密度脂蛋白(VLDL-C)、載脂蛋白A1(ApoA1)及載脂蛋白B100(ApoB100)水平。選取50例健康兒童作為對照。KD患兒在治療前行超聲心動圖檢查,根據超聲心動圖顯示將KD組再分為冠狀動脈病變組(CAL組,n=31)和非冠狀動脈病變組(NCAL,n=51)。 結果 治療前,KD患兒TC、ApoA1、HDLC降低,TG、LDL-C升高,與正常兒童相比有統計學意義(Plt;0.05)。KD患兒CAL組較NCAL組變化更明顯,有統計學意義(Plt;0.05)。VLDL-C和ApoB100水平KD患兒與正常兒童比較、NCAL組與CAL組比較變化均不明顯(Pgt;0.05)。治療后與治療前相比,NCAL組TC、TG、HDL-C、LDL-C、ApoA1恢復正常(Plt;0.05)),而CAL組僅TC、LDL-C、ApoA1恢復正常(Plt;0.05)。 結論 KD患兒存在血脂代謝紊亂,TC、TG、HDL-C、LDL-C、ApoA1與冠狀動脈的損害有關,應早期進行干預。

      Release date:2016-09-08 09:49 Export PDF Favorites Scan
    • Analysis on Clinical Characteristics of Infectious Mononucleosis in Children

      【摘要】 目的 探討兒童傳染性單核細胞增多癥(IM)的臨床特點。 方法 回顧性分析2005年8月-2009年8月收治的151例IM患兒的癥狀、體征、實驗室檢查及治療效果。 結果 IM臨床表現以發熱、咽峽炎、肝脾和淋巴結腫大最常見,鼻塞、眼瞼浮腫也是重要體征。外周血出現異型淋巴細胞及EBV-IgM抗體檢測可幫助確診。更昔洛韋治療IM效果確切。 結論 應重視IM臨床特點,有助于早期診斷并提高確診率,應用更昔洛韋治療值得推廣。【Abstract】 Objective To investigate the clinical features of infectious mononucleosis (IM) in children. Methods A total of 151 children with infectious mononucleosis admitted from August 2005 to August 2009 were reviewed. The symptoms, signs, laboratory tests, and treatment of infectious mononucleosis were analyzed. Results Fever, angina, hepatomegaly, splenomegaly, and swollen lymph nodes were the most common clinical manifestations of IM. Nasal congestion and eyelid edema were also two important signs. Atypical lymphocytes in peripheral blood and EBV antibody (VCA-IgM) could help confirm the diagnosis. The antiviral treatment with ganciclovir was effective for infectious mononucleosis. Conclusion Clinical features of infectious mononucleosis are helpful to the diagnosis. Treatment with ganciclovir should be promoted.

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