超敏肌鈣蛋白T與肌酸激酶同工酶在心絞痛患者中的檢出水平分析_West China Medical Journal

Authors：

 羅招川 , 林良才

什邡市人民醫院心血管內科（四川什邡 618400）;

Corresponding?author：

Keywords：

超敏肌鈣蛋白T; 肌酸激酶同工酶; 心絞痛

DOI：

10.7507/1002-0179.20160025

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

目的探討超敏肌鈣蛋白T（hs-TnT）與肌酸激酶同工酶（CK-MB）在心絞痛患者血清表達的水平差異及臨床意義。方法將2012年1月-2013年12月收治的168例疑似心絞痛患者，均以冠狀動脈造影結果分為無或輕病變組（單支冠狀動脈狹窄＜50%，64例），臨界病變組（單支冠狀動脈狹窄50%～70%，53例），心絞痛組（單支冠狀動脈＞70%或多支冠狀動脈狹窄＞50%，51例），入院后4 h抽靜脈血檢查hs-TnT與CK-MB，比較各組間相關數值差異。結果 hs-TnT在各組中差異有統計學意義（P＜0.05），并隨冠狀動脈狹窄病變程度加重而升高，CK-MB各組之間差異無統計學意義（P＞0.05）。結論 hs-TnT對心絞痛型冠狀動脈粥樣硬化性心臟病有預測作用，在心絞痛患者早期就能很好表達出，且隨著病變程度加重，hs-TnT水平開高，CK-MB對早期心絞痛患者無顯著臨床意義。

Citation： 羅招川, 林良才. 超敏肌鈣蛋白T與肌酸激酶同工酶在心絞痛患者中的檢出水平分析. West China Medical Journal, 2016, 31(1): 98-99. doi: 10.7507/1002-0179.20160025 Copy

1.	Laufer EM, Mingels AM, Winkens MH, et al. The extent of coronary atherosclerosis is associated with increasing circulating levels of high sensitive cardiac troponin T[J]. Arterioscler Thromb Vasc Biol, 2010, 30(6):1269-1275.
2.	孫偉峰, 楊莉. 高敏心臟肌鈣蛋白在冠狀動脈粥樣硬化性心臟病的研究進展[J]. 心血管病學進展, 2012, 33(6):751-754.
3.	蔡英, 周曉茜, 于萍, 等. 血清超敏肌鈣蛋白T在急性冠狀動脈綜合征患者中危險分層及預后價值的探討[J]. 臨床心血管病雜志, 2011, 27(7):507-510.
4.	Feng YJ, Chen C, Fallon JT, et al. Comparison of cardiac troponin I, creatine kinase-MB, and myoglobin for detection of acute ischemic myocardial injury in a swine model[J]. Am J Clin Pathol, 1998, 110(1):70-77.
5.	Sabatine MS, Morrow DA, De Lemos JA, et al. Detection of acute changes in circulating troponin in the setting of transient stress test-induced myocardial ischaemia using an ultrasensitive assay:results from TIMI 35[J]. Eur Heart J, 2009, 30(2):162-169.
6.	Sehulz O, Kromer A. Cardiac troponin I:a potential maker of exercise intolerance in patients with moderate heart failure[J]. Am Heart J, 2002, 144(2):351-358.
7.	Ivandic BT, Spanuth E, Kleber M, et al. High-sensitivity troponin T improves the prognostic value of N-terminal pro-B-type natriuretic peptide in patients with stable coronary artery disease:results from the LURIC Study[J]. Clin Chem Lab Med, 2011, 49(6):1053-1058.

1. Laufer EM, Mingels AM, Winkens MH, et al. The extent of coronary atherosclerosis is associated with increasing circulating levels of high sensitive cardiac troponin T[J]. Arterioscler Thromb Vasc Biol, 2010, 30(6):1269-1275.
2. 孫偉峰, 楊莉. 高敏心臟肌鈣蛋白在冠狀動脈粥樣硬化性心臟病的研究進展[J]. 心血管病學進展, 2012, 33(6):751-754.
3. 蔡英, 周曉茜, 于萍, 等. 血清超敏肌鈣蛋白T在急性冠狀動脈綜合征患者中危險分層及預后價值的探討[J]. 臨床心血管病雜志, 2011, 27(7):507-510.
4. Feng YJ, Chen C, Fallon JT, et al. Comparison of cardiac troponin I, creatine kinase-MB, and myoglobin for detection of acute ischemic myocardial injury in a swine model[J]. Am J Clin Pathol, 1998, 110(1):70-77.
5. Sabatine MS, Morrow DA, De Lemos JA, et al. Detection of acute changes in circulating troponin in the setting of transient stress test-induced myocardial ischaemia using an ultrasensitive assay:results from TIMI 35[J]. Eur Heart J, 2009, 30(2):162-169.
6. Sehulz O, Kromer A. Cardiac troponin I:a potential maker of exercise intolerance in patients with moderate heart failure[J]. Am Heart J, 2002, 144(2):351-358.
7. Ivandic BT, Spanuth E, Kleber M, et al. High-sensitivity troponin T improves the prognostic value of N-terminal pro-B-type natriuretic peptide in patients with stable coronary artery disease:results from the LURIC Study[J]. Clin Chem Lab Med, 2011, 49(6):1053-1058.

Previous Article
Study on the Model to Predict Thymus Volume with Two-dimensional Section Diameters among Fetuses

West China Medical Journal

超敏肌鈣蛋白T與肌酸激酶同工酶在心絞痛患者中的檢出水平分析

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Format

Content