Efficacy of Two Methods in Treating Severe Esophageal Varices with Endoscopic Variceal Ligation_West China Medical Journal

Authors：

 FANHe-zhang

Endoscope Room, Chengdu Public Health and Medical Center, Chengdu, Sichuan 610061, P. R. China;

Corresponding?author：

Keywords：

Cirrhosis; Esophageal varices; Endoscopic ligation

DOI：

10.7507/1002-0179.20140076

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Objective To observe the efficacy of dense ligation and non-dense ligation in treating severe esophageal varices. Methods Sixty cirrhotic patients with severe esophageal varices treated in our hospital between January 2009 and October 2011 were divided into two groups based on their operative ways.Group A was the dense ligation group including 32 patients,and group B was non-dense ligation group in which there were 28 patients.Six-shooter multi-band ligators were used for endoscopy.If the number of loop ligature collar was larger than six,it was regarded as dense ligation and the rest was regarded as non-dense ligation. Results In group A,one month after first ligature,six patients were basically cured,24 were greatly improved,and two did not respond to the treatment,with a total effective rate of 93.8% and an average ligation of 1.94 times.In group B,one month after first ligature,one patient was basically cured,24 were greatly improved,and three did not respond to the treatment,with a total effective rate of 89.3% and an average ligation of 2.75 times. Conclusion Dense ligation is a safe,reliable and effective approach for esophageal varices,which brings about a high disappearance rate of esophageal varices and reduced ligation frequency.

Citation： FANHe-zhang. Efficacy of Two Methods in Treating Severe Esophageal Varices with Endoscopic Variceal Ligation. West China Medical Journal, 2014, 29(2): 246-248. doi: 10.7507/1002-0179.20140076 Copy

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11.	萬曉強,鄭紫丹,楊杰.內鏡套扎治療50例肝硬化食管靜脈曲張破裂出血的臨床觀察[J].重慶醫學,2012,41(3):311-312.
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13.	Jaklewicz D,Rózański W,Wojtuń S,et al.Endoscopic methods of treatment of variceal haemorrhages[J].Pol Merkur Lekarski,2007,22(131):419-422.
14.	權啟鎮,齊鳳,王要軍,等.密集結扎法對食管靜脈曲張療效的評價[J].中華消化內鏡雜志,2001,18(5):276-278.
15.	曾慶貴,彭鵬,潘越.內鏡下密集套扎治療肝硬化食管胃靜脈曲張43例分析[J].重慶醫學,2011,40(30):3071-3072.
16.	熊錦華,陳力強,范公忍.胃鏡下套扎治療肝硬化食管靜脈曲張破裂出血的效果觀察[J].醫學綜述,2013,19(11):2075-2076.
17.	楊瑞權.食管靜脈曲張破裂出血套扎治療的體會[J].齊齊哈爾醫學院學報,2009,30(12):1455-1456.

1. 馬軍,李建生,段芳齡.BavenoⅣ門脈高壓診斷和治療共識[J].胃腸病學和肝臟病學雜志,2007,16(1):22-24.
2. 中華醫學會消化內鏡學分會.食管胃底靜脈曲張內鏡下診斷和治療規范試行方案[J].現代實用醫學,2002,21(9):507-509.
3. Tsoi KK,Ma TK,Sung JJ.Endoscopy for upper gastrointestinal bleeding:how urgent is it?[J].Nat Rev Gastroenterol Hepatol,2009,6(8):463-469.
4. Schepis F,Cammà C,Niceforo D,et al.Which patients with cirrhosis should undergo endoscopic screening for esophageal varices detection [J].Hepatology,2001,33(2):333-338.
5. 蔣曉渠,陳世耀,王慧.食管胃靜脈曲張破裂出血患者死亡危險因素分析[J].胃腸病學,2011,16(2):90-93.
6. 楊云生,令狐恩強.食管胃曲張靜脈破裂出血的內鏡治療[J].中華消化內鏡雜志,2004,21(3):152-153.
7. 黃任翔.食管胃靜脈曲張破裂出血的內鏡治療進展[J].胃腸病學,2011,16(1):51-53.
8. 高磊,馬超.肝硬化門脈高壓癥并食管胃靜脈曲張微創治療32例的臨床觀察[J].安徽醫學,2009,30(10):1221-1223.
9. 呂洪敏,向慧玲,張惠真,等.內鏡密集與非密集套扎治療重度食管靜脈曲張256例[J].世界華人消化雜志,2008,16(18):2048-2051.
10. 萬曉強,鄭紫丹,楊杰.肝硬化食管靜脈曲張出血胃鏡下套扎治療的療效[J].西南國防醫藥,2011,21(11):1182-1184.
11. 萬曉強,鄭紫丹,楊杰.內鏡套扎治療50例肝硬化食管靜脈曲張破裂出血的臨床觀察[J].重慶醫學,2012,41(3):311-312.
12. Villanueva C,Piqueras M,Aracil C,et al.A randomized controlled trial comparing ligation and sclerotherapy as emergency endoscopic treatment added to somatostatin in acute variceal bleeding[J].J Hepatol,2006,45(4):560-567.
13. Jaklewicz D,Rózański W,Wojtuń S,et al.Endoscopic methods of treatment of variceal haemorrhages[J].Pol Merkur Lekarski,2007,22(131):419-422.
14. 權啟鎮,齊鳳,王要軍,等.密集結扎法對食管靜脈曲張療效的評價[J].中華消化內鏡雜志,2001,18(5):276-278.
15. 曾慶貴,彭鵬,潘越.內鏡下密集套扎治療肝硬化食管胃靜脈曲張43例分析[J].重慶醫學,2011,40(30):3071-3072.
16. 熊錦華,陳力強,范公忍.胃鏡下套扎治療肝硬化食管靜脈曲張破裂出血的效果觀察[J].醫學綜述,2013,19(11):2075-2076.
17. 楊瑞權.食管靜脈曲張破裂出血套扎治療的體會[J].齊齊哈爾醫學院學報,2009,30(12):1455-1456.

West China Medical Journal

Efficacy of Two Methods in Treating Severe Esophageal Varices with Endoscopic Variceal Ligation

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