The Significance of Endoscopic Punctiform Erosion around Appendiceal Orifice with Diffused Inflammation in Left Semicolon in the Diagnosis of Ulcerative Colitis_West China Medical Journal

Authors：

 DENGPeng , GANTao ,  WUJun-chao

Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding?author：

WUJun-chao, Email: wujunchao615@qq.com

Keywords：

Ulcerative colitis; Skip lesion; Appendiceal orifice

DOI：

10.7507/1002-0179.20140077

Video：

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Abstract Full text Figures/Tables Video References Cited by

Objective To investigate the significance of endoscopic punctiform erosion around appendiceal orifice with diffused inflammation in left semicolon in the diagnosis of ulcerative colitis. Methods Twenty-nine patients with endoscopic punctiform erosion around appendiceal orifice with diffused inflammation in left semicolon treated in West China Hospital from January 2007 to November 2012 were included in our study.Patients with either edema,ulcer,polyps around the appendiceal orifice,inflammation in the ascending colon or transverse colon,or segmental inflammation in left semicolon were excluded.The endoscopic characteristic changes and the final diagnosis were compared by means of the pathological biopsy. Results Of the total 29 patients with characteristic changes under the endoscope,26 patients were eventually diagnosed to have left-sided ulcerative colitis,one was identified to be with Cronh's disease,and the remaining two patients could not be classified. Conclusion Our findings suggest that the characteristic changes under the endoscope may help the diagnosis of ulcerative colitis.

Citation： DENGPeng, GANTao, WUJun-chao. The Significance of Endoscopic Punctiform Erosion around Appendiceal Orifice with Diffused Inflammation in Left Semicolon in the Diagnosis of Ulcerative Colitis. West China Medical Journal, 2014, 29(2): 249-251. doi: 10.7507/1002-0179.20140077 Copy

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2.	歐陽欽.潰瘍性結腸炎臨床診斷指南[J].臨床消化病雜志,2007,19(1):4-6.
3.	中華醫學會消化病學分會炎癥性腸病協作組.對我國炎癥性腸病診斷治療規范的共識意見(2007年,濟南)[J].中華消化雜志,2007,27(8):545-550.
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9.	Matsumoto T,Nakamura S,Shimizu M,et al.Significance of appendiceal involvement in patients with ulcerative colitis[J].Gastrointest Endosc,2002,55(2):180-185.
10.	Radford-Smith GL,Edwards JE,Purdie DM,et al.Protective role of appendiectomy on onset and severity of ulcerative colitis and Crohn's disease[J].Gut,2002,51(6):808-813.
11.	Cosnes J,Carbonnel F,Beaugerie L,et al.Effect of appendicectomy on course of ulcerative colitis[J].Gut,2002,51(6):803-807.
12.	Mizoguchi A,Mizoguchi E,Chiba C,et al.Role of appendix in the development of imflammatory bowel diease in the TCR-a mutant mice[J].J Exp Med,1996,184(2):707-715.
13.	Yamagishi N,Iizuka B,Nakamura T,et al.Clinical and colonoscopic investigation of skipped periappendiceal lesions in ulcerative colitis[J].Scand J Gastroenterol,2002,37(2):177-182.
14.	Lucci E,Lattuneddu A,Valpiani D,et al.Skip lesion of the cecum associated with proctitis:an atypical case of ulcerative colitis[J].Dig Liver Dis,2004,36(12):847-851.
15.	Chiba M,Yamano H,Fujiwara K,et al.Lymph folliculitis in ulcerative colitis[J].Scand J Gastroenterol,2001,36(3):332-336.
16.	D'Haens G,Geboes K,Peeters M,et al.Patchy cecal inflammation associated with distal ulcerative colitis:a prospective endoscopic study[J].Am J Gastroenterol,1997,92(8):1275-1279.
17.	蘭永臻,王朔,劉曉慧,等.闌尾口周圍黏膜非連續性病變對非全結腸型潰瘍性結腸炎診斷價值的探討[J].臨床薈萃,2008,23(13):943-944.
18.	Ladefoged K,Munck LK,Jorgensen F,et al.Skip inflammation of the appendiceal orifice:a prospective endoscopic study[J].Scand J Gastroenterol,2005,40(10):1192-1196.

1. Cohen T,Pfeffer RB,Valensi Q. "Ulcerative appendicitis" occurring as a skip lesion in chronic ulcerative colitis:report of a case[J].Am J Gastroenterol,1974,62(2):151-155.
2. 歐陽欽.潰瘍性結腸炎臨床診斷指南[J].臨床消化病雜志,2007,19(1):4-6.
3. 中華醫學會消化病學分會炎癥性腸病協作組.對我國炎癥性腸病診斷治療規范的共識意見(2007年,濟南)[J].中華消化雜志,2007,27(8):545-550.
4. Massac E Jr,Rawlings L,Kurtz L.Segmental ulcerative colitis:a case report and review of the literature[J].J Natl Med Assoc,1982,74(3):286-288.
5. Rubin DT,Rothe JA.The peri-appendiceal red patch in ulcerative colitis:review of the University of Chicago experience[J].Dig Dis Sci,2010,55(12):3495-3501.
6. Naves JE,Lorenzo-Zú?iga V,Marín L,et al.Long-term outcome of patients with distal ulcerative colitis and inflammation of the appendiceal orifice[J].J Gastrointestin Liver Dis,2011,20(4):355-358.
7. Perry WB,Opelka FG,Smith D,et al.Discontinuous appendiceal involvement in ulcerative colitis:pathology and clinical correlation[J].J Gastrointest Surg,1999,3(2):141-144.
8. Hokama A,Ihama Y,Chinen H,et al.Appendiceal orifice inflammation in ulcerative colitis[J].Dig Dis Sci,2010,55(4):1189.
9. Matsumoto T,Nakamura S,Shimizu M,et al.Significance of appendiceal involvement in patients with ulcerative colitis[J].Gastrointest Endosc,2002,55(2):180-185.
10. Radford-Smith GL,Edwards JE,Purdie DM,et al.Protective role of appendiectomy on onset and severity of ulcerative colitis and Crohn's disease[J].Gut,2002,51(6):808-813.
11. Cosnes J,Carbonnel F,Beaugerie L,et al.Effect of appendicectomy on course of ulcerative colitis[J].Gut,2002,51(6):803-807.
12. Mizoguchi A,Mizoguchi E,Chiba C,et al.Role of appendix in the development of imflammatory bowel diease in the TCR-a mutant mice[J].J Exp Med,1996,184(2):707-715.
13. Yamagishi N,Iizuka B,Nakamura T,et al.Clinical and colonoscopic investigation of skipped periappendiceal lesions in ulcerative colitis[J].Scand J Gastroenterol,2002,37(2):177-182.
14. Lucci E,Lattuneddu A,Valpiani D,et al.Skip lesion of the cecum associated with proctitis:an atypical case of ulcerative colitis[J].Dig Liver Dis,2004,36(12):847-851.
15. Chiba M,Yamano H,Fujiwara K,et al.Lymph folliculitis in ulcerative colitis[J].Scand J Gastroenterol,2001,36(3):332-336.
16. D'Haens G,Geboes K,Peeters M,et al.Patchy cecal inflammation associated with distal ulcerative colitis:a prospective endoscopic study[J].Am J Gastroenterol,1997,92(8):1275-1279.
17. 蘭永臻,王朔,劉曉慧,等.闌尾口周圍黏膜非連續性病變對非全結腸型潰瘍性結腸炎診斷價值的探討[J].臨床薈萃,2008,23(13):943-944.
18. Ladefoged K,Munck LK,Jorgensen F,et al.Skip inflammation of the appendiceal orifice:a prospective endoscopic study[J].Scand J Gastroenterol,2005,40(10):1192-1196.

West China Medical Journal

The Significance of Endoscopic Punctiform Erosion around Appendiceal Orifice with Diffused Inflammation in Left Semicolon in the Diagnosis of Ulcerative Colitis

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