Clinical Characteristics of Acute Kidney Injury in Hospitalized Patients with Chronic Obstructive Pulmonary Disease_West China Medical Journal

Authors：

 LIUAn-li ¹ , LIUYing ¹ , LIZhi-lian ² , CHENZi-xing ³ , YEGuang-lin ³ , TAOYi-ming ² , CHENYuan-han ² ,  LIANGXin-ling ²

1. Department of Respiratory Medicine, the First People's Hospital of Longquanyi District of Chengdu City, Chengdu, Sichuan 610100, P. R. China;
2. Department of Nephrology, People's Hospital, Guangzhou, Guangdong 510080, P. R. China;
3. Department of Respiratory Medicine, People's Hospital, Guangzhou, Guangdong 510080, P. R. China;

Corresponding?author：

LIANGXin-ling, Email: xinlingliang@yahoo.com

Keywords：

Acute kidney disease; Chronic obstructive pulmonary disease; Adverse prognosis; Risk factor

DOI：

10.7507/1002-0179.20140073

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To investigate the role on adverse prognosis and risk factors of acute kidney injury (AKI) in hospitalized patients with chronic obstructive pulmonary disease (COPD). Methods Clinical data from hospitalized patients with COPD between January 2009 and June 2012 were studied retrospectively.AKI was diagnosed and classified by AKIN criterion. Results Three hundred and sixty-nine patients were enrolled,among whom 69(18.6%) were complicated with AKI.The patients with AKI were older,and had higher levels of hemoglobin,hematocrit value and sodium concentration,and higher rates of comorbidities of diabetes mellitus,proteinuria and shock,compared with the controls.Those with AKI had a 24.1% increased risk for ventilator,121.5% for intensive care,and 89.8% for death.And a higher AKI grade was related to a worse prognosis.The increased risk of AKI was 142.1% for every 5-year increase of age,155.7% for every 0.1 increase of hematocrit value,70.5% for every 0.1 increase of sodium concentration,and 49.1%,89.2%,148.2% and 685.7% for being complicated with proteinuria,coronary artery disease,diabetes mellitus and shock. Conclusion AKI is associated with adverse prognosis in hospitalized patients with COPD.Age,proteinuria,increased levels of hematocrit value and sodium concentration,and comorbidities of coronary artery disease,diabetes mellitus and shock are independent risk factors for AKI

Citation： LIUAn-li, LIUYing, LIZhi-lian, CHENZi-xing, YEGuang-lin, TAOYi-ming, CHENYuan-han, LIANGXin-ling. Clinical Characteristics of Acute Kidney Injury in Hospitalized Patients with Chronic Obstructive Pulmonary Disease. West China Medical Journal, 2014, 29(2): 236-238. doi: 10.7507/1002-0179.20140073 Copy

1.	溫靜,程慶礫.老年急性腎損傷的研究進展[J].中華臨床醫師雜志,2011,5(23):7064-7066.
2.	Bellomo R,Ronco C,Kellum JA,et al.Acute renal failure-definition,outcome measures,animal models,fluid therapy and information technology needs:the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group[J].Crit Care,2004,8(4):R204-212.
3.	Chertow GM,Burdick E,Honour M,et al.Acute kidney injury,mortality,length of stay,and costs in hospitalized patients[J].J Am Soc Nephrol,2005,16(11):3365-3370.
4.	蔣芬,陳源漢,梁馨苓,等.急性腎損傷RIFLE與AKIN標準在重癥監護病房患者中的應用比較[J].中國危重病急救醫學,2011,23(12):741-744.
5.	朱再志,許志忠,戚剛.慢性阻塞性肺病并發急性腎損傷的臨床分析[J].華西醫學,2010,25(8):1539-1540.
6.	Ma YC,Zuo L,Chen JH,et al.Modified glomerular filtration rate estimating equation for Chinese patients with chronic kidney disease[J].J Am Soc Nephrol,2006,17(10):2937-2944.
7.	Mehta RL,Kellum JA,Shah SV,et al.Acute Kidney Injury Network:report of an initiative to improve outcomes in acute kidney injury[J].Crit Care,2007,11(2):R31.
8.	中華醫學會心血管病學分會.慢性心力衰竭診斷治療指南[J].中華心血管病雜志,2007,35(12):1076-1095.
9.	Kortgen A,Niederprum P,Bauer M.Implementation of an evidence-based "standard operating procedure" and outcome in septic shock[J].Crit Care Med,2006,34(4):943-949.
10.	Grams M,Coresh J.Proteinuria and risk of acute kidney injury[J].Lancet,2010,376(9758):2046-2048.
11.	邢學忠,王海軍,黃初林,等.非心臟外科術后危重患者急性腎損傷危險模型的建立和驗證[J].中華臨床醫師雜志,2013,7(1):151-155.
12.	Weber-Mzell D,Kotanko P,Schumacher M,et al.Coronary anatomy predicts presence or absence of renal artery stenosis.A prospective study in patients undergoing cardiac catheterization for suspected coronary artery disease[J].Eur Heart J,2002,23(21):1684-1691.

1. 溫靜,程慶礫.老年急性腎損傷的研究進展[J].中華臨床醫師雜志,2011,5(23):7064-7066.
2. Bellomo R,Ronco C,Kellum JA,et al.Acute renal failure-definition,outcome measures,animal models,fluid therapy and information technology needs:the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group[J].Crit Care,2004,8(4):R204-212.
3. Chertow GM,Burdick E,Honour M,et al.Acute kidney injury,mortality,length of stay,and costs in hospitalized patients[J].J Am Soc Nephrol,2005,16(11):3365-3370.
4. 蔣芬,陳源漢,梁馨苓,等.急性腎損傷RIFLE與AKIN標準在重癥監護病房患者中的應用比較[J].中國危重病急救醫學,2011,23(12):741-744.
5. 朱再志,許志忠,戚剛.慢性阻塞性肺病并發急性腎損傷的臨床分析[J].華西醫學,2010,25(8):1539-1540.
6. Ma YC,Zuo L,Chen JH,et al.Modified glomerular filtration rate estimating equation for Chinese patients with chronic kidney disease[J].J Am Soc Nephrol,2006,17(10):2937-2944.
7. Mehta RL,Kellum JA,Shah SV,et al.Acute Kidney Injury Network:report of an initiative to improve outcomes in acute kidney injury[J].Crit Care,2007,11(2):R31.
8. 中華醫學會心血管病學分會.慢性心力衰竭診斷治療指南[J].中華心血管病雜志,2007,35(12):1076-1095.
9. Kortgen A,Niederprum P,Bauer M.Implementation of an evidence-based "standard operating procedure" and outcome in septic shock[J].Crit Care Med,2006,34(4):943-949.
10. Grams M,Coresh J.Proteinuria and risk of acute kidney injury[J].Lancet,2010,376(9758):2046-2048.
11. 邢學忠,王海軍,黃初林,等.非心臟外科術后危重患者急性腎損傷危險模型的建立和驗證[J].中華臨床醫師雜志,2013,7(1):151-155.
12. Weber-Mzell D,Kotanko P,Schumacher M,et al.Coronary anatomy predicts presence or absence of renal artery stenosis.A prospective study in patients undergoing cardiac catheterization for suspected coronary artery disease[J].Eur Heart J,2002,23(21):1684-1691.

West China Medical Journal

Clinical Characteristics of Acute Kidney Injury in Hospitalized Patients with Chronic Obstructive Pulmonary Disease

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content