NNT defines the number of patients who need to be treated in order to achieve one additional favorable outcome, and NNH is defined as the number of patients who must be treated with a therapy in order to have one additional patient suffer an adverse effect compared with the control treatment. This is the most important thing that should beconsidered before administering a treatment. NNT can also be used to assess the relative benefit or harm in the comparison of intervention versus positive control. If the effect is smaller in the intervention group than that in the control group, NNT should be used; if the effect is bigger in the intervention group than that in the control group, NNH should be used. When comparison is made between an intervention versus placebo, NNT and NNH are absolute outcomes; when an intervention is compared to a positive control, NNT and NNH are relative outcomes. RR or OR or RD may help to judge which comparator has bigger or smaller effect, and whether NNT or NNH should be used.
摘要:目的:總結胸心血管外科慢性傷口換藥的經驗。方法：2008年11月2009年4月我科共發生12例手術切口裂開病例，使用貝復濟噴灑創面，藻酸鈣敷料填塞創面，外用二層敷料固定，根據滲液情況決定更換敷料的頻率，高滲出時每天更換，中等滲出時每2天更換，少量滲出時每3天更換。結果：本組12例患者，11例患者傷口均達到二期愈合，平均愈合時間為（12±2）天，另外1例轉燒傷科行植皮術，后愈合。結論：通過聯合使用貝復濟和藻酸鈣敷料，使本組病例的滲出減少，創面肉芽生長迅速，傷口疼痛減輕或消失，傷口周圍皮膚免受浸漬，傷口快速愈合。Abstract: Objective: To introduce the methods of using streptogenin spray and the alginate dressing on Cardiac wound disruption. Methods: Our department had 12 cases of wound disruption from the November 2008 to the April 2009, We sprinkled the streptogenin spray to wound, then filled wound with the alginate dressing, finally fix wound with gauze and adhesive tape.According to the volume of the exudation, we decided how often to change the dressings. When the exudation volume was high ,We changed the dressing every day; While medium, We changed every two days ; When low ,We changed every three days. Results:Eleven 11 of 12 wounds got second phase of healing, the average healing time was (12±2) days. Conclusion: Using of the Streptogenin spray and the alginate dressing on disruption wound can reduce the exudation volume and wound pain, meanwhile it can progress the growth of granulation , so the wounds healed quickly.