目的 對康復新液治療消化道潰瘍的療效和安全性進行系統評價。 方法 計算機檢索Pubmed數據庫、中國學術期刊全文數據庫（CNKI）、中文科技期刊全文數據庫（VIP）、中國生物醫學文獻數據庫（CBM）、中文生物醫學期刊數據庫（CMCI），檢索日期為各數據建庫時間起至2011年5月30日止。納入的試驗類型為隨機對照試驗，康復新液與三聯療法、抗菌藥、抑制胃酸藥比較的試驗，或康復新液聯合三聯療法、抗菌藥、抑制胃酸藥與后者比較的試驗。采用Cochrane協作網的質量評價標準并用其提供的軟件RevMan 5.1軟件進行資料分析。結局的效應指標為胃鏡下潰瘍痊愈情況、臨床癥狀痊愈情況、臨床癥狀有效情況、幽門螺桿菌（HP）根除情況以及不良反應。 結果 共納入22篇隨機對照試驗（2 224例患者）進行系統評價，所納入的文獻質量偏低。統計分析結果顯示在潰瘍痊愈、臨床癥狀痊愈方面康復新液聯合質子泵抑制劑或加用抗幽門螺桿菌藥物與單用質子泵抑制劑或加用抗HP藥物相比，結果均有統計學意義，單用康復新液與質子泵抑制劑或H2受體拮抗劑比較以及康復新液聯合抗HP藥物與抗HP藥物比較，療效相當，結果無統計學意義。 結論 康復新液可以更有效地促進消化道潰瘍愈合以及改善臨床各種癥狀，但方法學方面亟待提高。
Objective To review the research progress on bone repair biomaterials with the function of recruiting endogenous mesenchymal stem cells (MSCs). Methods An extensive review of the relevant literature on bone repair biomaterials, particularly those designed to recruit endogenous MSCs, was conducted, encompassing both domestic and international studies from recent years. The construction methods and optimization strategies for these biomaterials were summarized. Additionally, future research directions and focal points concerning this material were proposed. Results With the advancement of tissue engineering technology, bone repair biomaterials have increasingly emerged as an ideal solution for addressing bone defects. MSCs serve as the most critical “seed cells” in bone tissue engineering. Historically, both MSCs and their derived exosomes have been utilized in bone repair biomaterials; however, challenges such as limited sources of MSCs and exosomes, low survival rates, and various other issues have persisted. To address these challenges, researchers are combining growth factors, bioactive peptides, specific aptamers, and other substances with biomaterials to develop constructs that facilitate stem cell recruitment. By optimizing mechanical properties, promoting vascular regeneration, and regulating the microenvironment, it is possible to create effective bone repair biomaterials that enhance stem cell recruitment. Conclusion In comparison to cytokines, phages, and metal ions, bioactive peptides and aptamers obtained through screening exhibit more specific and targeted recruitment functions. Future development directions for bone repair biomaterials will involve the modification of peptides and aptamers with targeted recruitment capabilities in biological materials, as well as the optimization of the mechanical properties of these materials to enhance vascular regeneration and adjust the microenvironment.