Evidence-based medicine database is a type of digital resource, which is based on principles of evidence-based medicine. It collects clinical evidence as a major content to serve clinical decision-making. This paper focused on various types of evidence-based databases, such as clinical practice guidelines, systematic reviews, and clinical trials. After collecting some representative databases, it analyzed and compared their contents, functions and characteristics, in attempt to enhance understanding of the current situation and trends of development of evidence-based medicine databases.
摘要:目的:探討16層螺旋CT圖像后處理技術對青少年特發性脊柱側凸的胸椎旋轉和椎弓根徑線變化特點及臨床價值。 方法:收集經臨床診治的青少年特發性脊柱側凸20例,運用16層螺旋CT掃描及圖像后處理技術,進行相關CT數據測量統計。結果:(1)脊柱胸椎側凸的頂椎及鄰近椎體均向凸側旋轉、后份向凹側旋轉,以頂椎旋轉最重,且凹側椎弓根徑線小于凸側,與側凸程度及方向具有相關性。(2)上、下終椎椎體旋轉及椎弓根徑線變化則較復雜,其椎體無旋轉或向相反方向旋轉,椎弓根徑線可凸側小于凹側,以上終椎明顯。結論:16層螺旋CT及圖像后處理技術,對顯示青少年特發性脊柱側凸胸椎旋轉及椎弓根徑線變化特征,可提供臨床擬訂手術方案的重要影像學依據。
Systematic review is an important method to obtain clinical decision evidence. The traditional systematic review is primarily conducted manually, which cannot meet the needs of rapid decision-making due to its high time and labor force cost as well as low efficiency. However, the development of information technology has laid the foundation for computer-aided systematic review methods. Attempts have been made to replace or enhance manual operations by introducing computer technology in all aspects of systematic review, thereby improving efficiency. This paper integrates the methodological research and its application of computer-aided systematic review both domestically and abroad from perspectives of literature acquisition, data processing and evidence evaluation. The aim of this paper is to understand the status quo and future trend in this field, and to provide reference for further researches related to automated systematic review technology.
Protein-energy wasting is one of the common complications of maintenance hemodialysis patients. It often causes decreased immune function, increased anemia, and decreased heart, brain, lung and other organ functions, resulting in decreased quality of life, decreased long-term survival rate, and increased mortality. This article discusses the causes, diagnosis, evaluation methods, intervention and prevention of protein-energy wasting in maintenance hemodialysis patients, and aims to provide a theoretical basis for evaluating the nutritional status, early intervention for protein-energy wasting, and improving prognosis and quality of life of maintenance hemodialysis patients.
ObjectiveTo understand the distribution of demographic sociological characteristics and co-morbidities among primiparous and multiparous pregnant women under the China's universal two-child policy, to provide baseline data for clinical high-risk management and medical resources allocation.MethodsWe included pregnant women from 24 hospitals in 16 provinces (municipality, autonomous region) of China and collected their demographic sociological characteristics and obstetrics information by questionnaires between September 19th, and November 20th, 2016. Then, we used descriptive analysis to present the distribution of demographic sociological characteristics and pregnancy co-morbidities among primiparous and multiparous women and compared differences between groups by t test or Chi-square test.ResultsAmong 12 403 investigated pregnant women, 8 268 (66.7%) were primiparous and 4 135 (33.3%) were multiparous, with highest proportion in East (931/2 008, 46.4%) and lowest in Northeast (385/2 179, 17.7%). Multiparous women, comparing to primiparous women, were more likely to be elderly than 35 years (accounting for 30.6% vs. 6.5%), lower educated with high school or below (29.7% vs. 16.9%), occupied in physical labor or unemployed (49.2% vs. 42.5%), non-local residents (12.7% vs. 10.5%), family annual income higher than 120 thousand yuan (41.3% vs. 33.3%), pre-pregnancy body mass index≥24 kg/m2 (13.6% vs. 9.9%), history of artificial abortions (44.9% vs. 24.0%), or pregnancies≥4 times (23.8% vs. 3.1%) and were less likely to receive assisted reproductive technology (2.3% vs. 4.7%). The most common co-morbidities were gynecology disease (5.5%), thyroid disease (5.4% in all women), blood system disease (5.0%), digestive system disease (4.2%) and hepatitis B infection (2.5%). Multiparous women, comparing to primiparous women, had higher proportions with blood system disease (5.7% vs. 4.7%), hepatitis B infection (3.1% vs. 2.2%) and chronic hypertension (0.6% vs. 0.2%), but lower proportions with thyroid diseases, polycystic ovary syndrome, and immune system diseases, whose distribution also showed regional differences.ConclusionThere existed distribution differences regarding demographic sociological characteristics and co-morbidities proportions between primiparous and multiparous women. Therefore, we should improve clinical risk management and medical resources allocation based on pregnant women’s baseline and gestational characteristics.