ObjectiveAnalyze the clinical features of epilepsy induced by tuberous sclerosis complex (TSC) to improve diagnosis and treatment level of this disease, and improve the prognosis. MethodsThe clinical data of 54 patients with epilepsy induced by TSC from May, 2012 to May, 2015 were analyzed together with the physical data, clinical presentations, EEG, imaging findings, treatment, prognosis and follow-up. Summarizing the clinical features of epilepsy induced by TSC. ResultsPatients with different epilepsy onset age, whether or not combined spasm, differences in intelligence status were statistically significant (P < 0.05); Patients with different gender, skin lesions, types of seizures, differences in intelligence status were no statistical significance (P > 0.05); Patients with different gender, epilepsy onset age, differences in patients with spasm were statistically significant (P < 0.05); Patients with different family history, skin lesions, types of seizures, differences in patients with spasm were not statistically significant (P > 0.05). Patients with different intelligence status, difference of medication quantity was statistically significant (P < 0.05); Patients with different gender, onset age, family history, skin lesions, whether or not combined spasm, types of seizures, difference of medication quantity was not statistically significant (P > 0.05). ConclusionsEpilepsy is the most common neurological manifestations in TSC, mostly onset in early childhood. Seizure types are different from one to another. Patients can be combined with skin damage and mental retardation. Positive rate of EEG and head imaging examination are high, seizure control rate is low. Patients need long-term follow-up and timely adjustment of treatment. Intelligence status is related to epilepsy onset age, spasm. Patients with spasm are related to different gender, epilepsy onset age. Medication quantity is related to intelligence status.
目的 探討鎖骨鉤鋼板并改良Weaver-Dunn技術治療Tossy Ⅲ型陳舊性肩鎖關節脫位的療效。 方法 2007年１月－2011年１月，對12例Tossy Ⅲ型陳舊性肩鎖關節脫位采用鎖骨鉤鋼板并改良Weaver-Dunn技術治療。其中3例為肩鎖關節脫位手術后再次發生脫位，2例合并鎖骨遠端骨折采用保守治療無效，余7例單純性陳舊性肩鎖關節脫位未經任何檢查治療。 結果 術后患者切口均Ⅰ期愈合，無神經血管損傷、無切口感染等并發癥。12例均獲隨訪，隨訪時間12～30個月。X線片示鎖骨復位情況良好，去除內固定后未見肩鎖關節脫位復發。肩鎖關節功能好，局部畸形消失，無肩周肌肉萎縮及肩周炎出現，鎖骨位置良好。手術療效評價：獲優10例，良2例，優良率100%。 結論 鎖骨鉤鋼板并改良Weaver-Dunn技術治療Tossy Ⅲ型陳舊性肩鎖關節脫位，復位固定滿意，韌帶重建易成功，肩關節功能恢復好，是一種治療陳舊性肩鎖關節脫位較理想的方法。