Taking advantages of the sparsity or compressibility inherent in real world signals, compressed sensing (CS) can collect compressed data at the sampling rate much lower than that needed in Shannon’s theorem. The combination of CS and low rank modeling is used to medical imaging techniques to increase the scanning speed of cardiac magnetic resonance (CMR), alleviate the patients’ suffering and improve the images quality. The alternating direction method of multipliers (ADMM) algorithm is proposed for multiscale low rank matrix decomposition of CMR images. The algorithm performance is evaluated quantitatively by the peak signal to noise ratio (PSNR) and relative l2 norm error (RLNE), with the human visual system and the local region magnification as the qualitative comparison. Compared to L + S, kt FOCUSS, k-t SPARSE SENSE algorithms, experimental results demonstrate that the proposed algorithm can achieve the best performance indices, and maintain the most detail features and edge contours. The proposed algorithm can encourage the development of fast imaging techniques, and improve the diagnoses values of CMR in clinical applications.
目的 觀察后路環形減壓治療胸腰椎爆裂骨折術后2～5年的臨床療效及并發癥發生情況。 方法 回顧性分析2007年1月－2011年3月23例胸腰椎椎體爆裂骨折患者資料，23例患者存在骨折壓迫硬膜合并神經癥狀，均予后路環形減壓。術后定期隨訪，采用日本骨科協會評估治療分數、美國脊髓損傷協會脊髓損傷分級評定臨床療效及神經功能改善情況，通過影像學資料觀察脊柱Cobb角變化情況。 結果 23例患者手術順利，經過2～5年的隨訪，出現術后腦脊液漏3例，尿路感染5例，經對癥處理后好轉。 結論 經椎弓根內側行椎體后壁切除，可良好減壓，避免神經擠壓繼發加重損傷，有利于神經功能恢復。
ObjectiveTo investigate the efficiency of double moxibustion combined with intermittent catheterization on urination diary in patients with neurogenic bladder (NB) after spinal cord injury (SCI).MethodsFrom August 2014 to August 2016, hospitalized patients with NB after SCI were reviewed retrospectively and classified into the moxibustion group and the routine group. The urination diary related indicators, International Urinary Incontinence Advisory Committee Urinary Incontinence Questionnaire Short Form (ICI-SQ-SF) score, and routine urine leucocyte count were collected.ResultsA total of 278 patients were enrolled in the study, in whom, the data of 96 were incomplete, and 26 got lost to follow-up. The routine group and the moxibustion group finally contained 70 and 86 respectively. There was no significant difference between the two groups in sex, age, average course of the disease, SCI segment or grading of injury (P>0.05). After 2 months treatment, the urine routine leucocyte count decreased to (5.72± 0.36)/μL in the routine group and (3.22±0.27)/μL in the moxibustion group, and the ICI-Q-SF score decreased to 8.61±0.45 in the routine group and 5.07±0.38 in the moxibustion group. The urine routine leucocyte count and ICI-Q-SF score were lower than those before treatment, and were lower in the moxibustion group than those in the routine group (P<0.05). In the 7th to 8th week, in the routine group, the average single urine volume was (300±70) mL, the interval between two micturition was (3.5±0.6) hours, the frequency of urinary incontinence was (3.3±0.4) times per week, and the average residual urine volume was (125±42) mL; in the moxibustion group, they were (326±78) mL, (3.8±1.1) hours, (2.3±0.3) times per week, and (103±37) mL, respectively. The indexes were not statistically significant different from those in the 1st to 2nd week (P>0.05), except the average single urine volume in the routine group and all the indexes in the moxibustion group (P<0.05). They were all better in the moxibustion group than those in the routine group (P<0.05).ConclusionThe treatment of moxibustion and intermittent catheterization may improve bladder function, reduce residual urine, reduce urinary incontinence and improve the quality of life for patients with NB after SCI.
Objective To review the research progress in the construction strategy and application of bone/cartilage immunomodulating hydrogels. Methods The literature related to bone/cartilage immunomodulating hydrogels at home and abroad in recent years was reviewed and summarized from the immune response mechanism of different immune cells, the construction strategy of immunomodulating hydrogels, and their practical applications. Results According to the immune response mechanism of different immune cells, the biological materials with immunoregulatory effect is designed, which can regulate the immune response of the body and thus promote the regeneration of bone/cartilage tissue. Immunomodulating hydrogels have good biocompatibility, adjustability, and multifunctionality. By regulating the physical and chemical properties of hydrogel and loading factors or cells, the immune system of the body can be purposively regulated, thus forming an immune microenvironment conducive to osteochondral regeneration. ConclusionImmunomodulating hydrogels can promote osteochondral repair by affecting the immunomodulation process of host organs or cells. It has shown a wide application prospect in the repair of osteochondral defects. However, more data support from basic and clinical experiments is needed for this material to further advance its clinical translation process.
目的 探討改良的經臍單孔腹腔鏡膽囊切除術的臨床可行性。 方法 回顧性分析2009年2月－2012年4月75例患者行改良經臍單孔腹腔鏡手術的臨床資料。其中39例膽囊結石，20例膽囊息肉，急性膽囊炎14例，急性膽囊炎伴穿孔2例。 結果 73例手術均成功完成，2例轉為傳統三孔腹腔鏡膽囊切除術后順利完成手術，無中轉開腹。平均手術時間為54.4 min （23～120 min）。術中出血量5～30 mL，平均(14.9 ± 5.10) mL。術后疼痛輕，恢復快，3 d后出院。隨訪1～10個月，未出現出血、漏膽、膽管損傷、消化道損傷、切口疝等并發癥。且瘢痕隱蔽，不易發現。 結論 改良后的經臍單孔腹腔鏡膽囊切除術安全可行，具有微創、經濟、恢復快等優點，具有推廣價值。