目的 通過分析影響四川地區慢性乙型肝炎患者抗病毒治療依從性的因素，探討提高患者治療依從性的策略。 方法 選擇2011年4月－2012年4月在四川大學華西醫院接受核苷（酸）類似物抗病毒治療的324例慢性乙型肝炎患者作為研究對象。采用問卷調查的方法，對患者一般情況、心理狀態、文化程度、經濟情況、疾病認知情況、抗病毒療效、服藥持續性等相關因素進行分析，評估這些因素對患者治療依從性的影響。 結果 324例患者中能夠完全遵照醫囑者78例（24.07%），不能完全依從者246例（75.93%）。心理狀態良好者132例（40.74%），其中依從性良好者54例；心理負擔較重者192例（59.26%），其中依從性良好者24例。初中及以上學歷204例（62.96%），依從性良好者72例；初中以下學歷者120例（37.04%），依從性良好者僅6例。不同心理狀態、文化程度的患者依從率差異有統計學意義。患者經濟狀況、年齡差異對于依從性也有一定影響。 結論 慢性乙型肝炎患者對抗病毒治療的依從性與心理狀態、文化程度者及經濟狀況密切相關。改善患者醫療費用償付能力，對患者進行疾病認知教育以及減少社會歧視等措施有助于提高患者治療依從性。
Objective To assess the current status of medical waste management and classification disposal in hospitals across Hubei Province, providing a scientific basis for optimizing medical waste disposal strategies and promoting waste minimization, harmless treatment, and resource utilization. Methods A random sample survey was conducted on medical and health institutions in Hubei Province between January 8 and January 17, 2025. The self-made survey questionnaire was used to survey and analyze the medical waste management and classification disposal in medical and health institutions. Results A total of 257 medical and health institutions were surveyed. Among them, there were 93 tertiary hospitals (36.19%), 75 secondary hospitals (29.18%), 77 primary hospitals (29.96%), and 12 non-graded medical institutions (4.67%). The overall compliance rate for medical waste management and training exceeded 90%. In terms of medical waste supervision sections, compliance rates in primary hospitals and non-graded hospitals were 77.92% (60/77) and 58.33% (7/12), respectively. The compliance rate for medical waste classification and disposal was above 90%, with a 100% (221/221) compliance rate for the disposal of placentas from normal deliveries. However, the standardized disposal rates for “fetal tissues from pregnancies under 16 weeks or weighing less than 500 grams”, “amputation and other human tissues (or organs)” and “dead fetus” were 81.45% (180/221), 44.65% (96/215), and 79.64% (176/221), respectively. Additionally, 87.16% (224/257) of healthcare institutions classified single-use soft infusion bottles (bags) as recyclable waste, but significant variations were observed in the disposal of uncontaminated waste (e.g., empty disinfectant bottles, empty dialysis fluid barrels, oxygen humidifier bottles, and orthopedic casting materials). Furthermore, 99.61% (256/257) of hospitals provided protective equipment for medical waste handlers, 91.83% (236/257) conducted regular health examination to them, and 97.28% (250/257) had established needle stab reporting systems and related training programs. Conclusions Medical waste management and classification in hospitals across Hubei Province are largely standardized. However, the certain categories of medical waste still require stricter regulation and oversight.