Abstract: Intravenous leiomyomatosis (IVL) is a rare kind of uterine myoma. It is a benign smooth muscle tumor with invading growth pattern. The tumor extends into venous channels, but rarely invades tissues. It grows along the refluxing direction of the venous channels, uterine vein, ovarian vein, and beyond the uterus, extends into the inferior vena cava till the right atrium or pulmonary arteries, resulting in intracardiac leiomyomatosis (ICL). At present, the tumor can be detected by ultrasonic waves, computer tomography and magnetic resonance imaging. The main ICL therapy is surgery which is divided into onestage operation and twostage operation in which the key is the complete tumor excision. Most sufferers have a good prognosis, but there are possibilities of recurrence. Missed diagnosis and misdiagnosis are not uncommon, because the disease is rare with hided and diversified clinical manifestations. It is fatal without special characteristics. For a better understanding of ICL, the recent research and treatment of ICL are reviewed.
ObjectiveTo conclude the current status and research progress on the pathological mechanism, development and management of pancreatic cancer-associated diseases and provide evidence for intervention of such diseases.MethodThe relevant literatures were reviewed, and the research progress on pancreatic cancer-associated diseases were summarized.ResultsThere are many types of pancreatic cancer-associated diseases, and common diseases included pancreatic intraepithelial neoplasia, intraductal papillary mucinous neoplasm, mucinous cystic neoplasm, diabetes, and chronic pancreatitis. Although management and following-up about this kind of diseases remain controversial, the basic consensus has been reached.ConclusionAdequate follow-up is required for patients with pancreatic cancer-associated disease, individualized interventions should be taken if necessary.
Electroencephalography (EEG) signals are strongly correlated with human emotions. The importance of nodes in the emotional brain network provides an effective means to analyze the emotional brain mechanism. In this paper, a new ranking method of node importance, weighted K-order propagation number method, was used to design and implement a classification algorithm for emotional brain networks. Firstly, based on DEAP emotional EEG data, a cross-sample entropy brain network was constructed, and the importance of nodes in positive and negative emotional brain networks was sorted to obtain the feature matrix under multi-threshold scales. Secondly, feature extraction and support vector machine (SVM) were used to classify emotion. The classification accuracy was 83.6%. The results show that it is effective to use the weighted K-order propagation number method to extract the importance characteristics of brain network nodes for emotion classification, which provides a new means for feature extraction and analysis of complex networks.
In order to promote the effective development of hospital day surgery mode, a construction method of information management platform that meets the characteristics of day surgery mode is presented. By analyzing the business process of the day surgery mode, the system architecture of the information platform is given; according to the difficulty of the surgical scheduling, the two-stage surgical scheduling algorithm based on the ranking theory is given; by analyzing the day surgery data statistically, a multi-angle surgical index analysis module is provided. The information management of the day surgery mode has been realized, and the work efficiency has been improved. A reasonable day surgery information platform construction can help to optimize the daytime surgical procedure and promote the smooth development of day surgery.
目的 比較無創雙水平正壓通氣(BiPAP)平均容積保證壓力支持(AVAPS)模式與同步/時間控制(S/T)模式在肥胖的慢性阻塞性肺疾病(COPD)患者并發急性Ⅱ型呼吸衰竭中的治療作用。 方法 選取2012年3月-2013年6月入院治療且體質量指數(BMI)>25 kg/m2的COPD發生急性Ⅱ型呼吸衰竭患者36例,按數字隨機表法分為AVAPS組與S/T組。兩組的基礎治療相同,AVAPS組采用飛利浦偉康V60呼吸機BiPAP AVAPS模式進行無創通氣治療,S/T組采用相同機型BiPAP S/T模式治療。分別比較兩組患者治療1、6、24、72 h的格拉斯高昏迷(GCS)評分變化、血氣分析結果、呼吸機監測數據。 結果 AVAPS組患者在最初治療的6 h內GCS評分高于S/T組[1 h:(13.2 ± 0.6)、(11.9 ± 0.6) 分,P<0.05;6 h:(13.8 ± 0.5)、(12.1 ± 0.6)分,P<0.05];24 h內的動脈血氣酸堿度pH值改善[1 h:7.31 ± 0.03、7.26 ± 0.02,P<0.05;6 h:7.37 ± 0.05、7.31 ± 0.04,P<0.05];24 h:7.40 ± 0.04、7.33 ± 0.03,P<0.05]及二氧化碳分壓下降[1 h:(65.2 ± 5.1)、(69.5 ± 4.1)mm Hg(1 mm Hg=0.133 kPa),P<0.05;6 h:(61.4 ± 4.2)、(66.7 ± 4.3) mm Hg,P<0.05;24 h:(58.2 ± 4.5)、(64.3 ± 5.4) mm Hg,P<0.05)]優于S/T組,24 h內淺快呼吸指數低于S/T組[1 h:(35.2 ± 8.1)、(62.8 ± 13.2)次/(min·L),P<0.05];6 h(33.4 ± 7.8) 、(54.8 ± 11.6)次/(min·L),P<0.05],同時,減少了額外的人工參數調整次數[3.4 ± 1.1、1.2 ± 0.6),P<0.05] 結論 對超重的COPD合并急性Ⅱ型呼吸衰竭患者采用AVAPS模式進行無創通氣治療,較S/T模式能更快地恢復意識水平,更快地降低血二氧化碳分壓、改善pH值,同時減少了呼吸治療師的人工操作次數。
ObjectiveTo compare clinical efficacy between transumbilical three-port laparoscopic surgery (TU-TPLS) and transumbilical single-incision laparoscopic surgery (TU-SILS) in repair of acute peptic ulcer perforation. MethodsThe patients with acute peptic ulcer perforation who underwent TU-TPLS or TU-SILS in Chengdu Second People’s Hospital Affiliated to Sichuan University from January 2022 to December 2024 were retrospectively collected, and then were divided into the TU-TPLS group and TU-SILS group. The operation time, postoperative 24 h incision pain score (visual analogue scale) , postoperative hospital stay, total hospitalization cost, incision scar score (Vancouver scar scale), comprehensive satisfaction, and postoperative complications were compared between the two groups. ResultsA total of 105 patients met the inclusion criteria were enrolled, comprising 50 patients in the TU-TPLS group and 55 patients in the TU-SILS. There were no statistically significant differences in baseline characteristics between the two groups, such as gender, age, body mass index, perforation site, perforation diameter, and Boey score (all P>0.05). Postoperatively, the TU-TPLS group demonstrated significantly lower visual analogue scale pain score at 24 h compared to the TU-SILS group [(2.34±0.63) score vs. (3.22±1.05) score, P<0.001] and significantly higher comprehensive satisfaction score [(7.60±0.86) score vs. (7.02±1.01) score, P=0.002]. However, no statistically significant differences were observed between the TU-TPLS group and TU-SILS group regarding operative time [(71.84±10.51) min vs. (69.78±7.98) min, P=0.257], postoperative hospital stay [(10.35±2.08) d vs. (9.96±1.75) d, P=0.310], or total hospitalization costs [(20 856.23±4 095.73) yuan vs. (19 988.83±2 933.43) yuan, P=0.212]. The incidence of umbilical wound infection was 1 case in the TU-TPLS group and 3 cases in the TU-SILS group (P=0.619). Postoperative residual intra-abdominal infection occurred in 2 cases in the TU-TPLS group and 1 case in the TU-SILS group (P=0.604). Incisional bleeding occurred in 0 case in the TU-TPLS group and 1 case in the TU-SILS group (P>0.999). Furthermore, there was no statistically significant difference in the scar assessment score between the TU-TPLS group and TU-SILS group [(3.11±1.13) score vs. (2.92±0.70) score, P=0.301] at the 2-month postoperative follow-up. ConclusionsBoth TU-TPLS and TU-SILS have achieved good therapeutic effects in treatment of acute peptic ulcer perforation. However, TU-TPLS has more advantages over TU-SILS. TU-TPLS causes milder incision pain, leads to higher patient satisfaction, and does not require special equipment.