Fibropolycystic liver diseases (FLDs) is a rare genetic disorder, including bile duct hamartomas, congenital hepatic fibrosis, polycystic liver disease, Caroli’s disease, and choledochal cysts. Fibropolycystic liver diseases has received little clinical attention and exhibits a variety of imaging manifestations, leading to a high likelihood of missed diagnosis and misdiagnosis. Through this case, we delineate the characteristic imaging manifestations of the disease and its underlying pathological mechanisms. Our objective is to enhance readers' comprehension of the disease and thereby reduce the rate of missed diagnosis and misdiagnosis of the disease.
ObjectiveTo analyze the symptom characteristics and influencing factors in order to provide reference for symptom management of patients with esophageal cancer after operation.MethodsA total of 216 esophageal cancer patients, including 180 males and 36 females with an average age of 63.7±8.3 years, who underwent surgical operation in our hospital from March to October 2018 were recruited and investigated with self-designed symptom questionnaire at 1 month after surgery.ResultsThe top five symptoms were acid reflux (48.6%), cough (42.6%), dysphagia (40.7%), hoarseness (12.0%), and diarrhea (11.6%). Women were more prone to acid reflux (OR=2.053), fatigue (OR=1.932), chest pain (OR=3.681), sleep disturbance (OR=2.419), abdominal pain (OR=3.882), nausea (OR=3.014) and vomiting (OR=2.505). Patients over 60 years were more prone to dysphagia (OR=2.274). Patients with lower thoracic esophageal cancer had a higher incidence of dysphagia compared with patients with carcinoma of esophagogastric junction (OR=0.326). Patients who had neoadjuvant chemotherapy were more likely to suffer acid reflux (OR=1.594). Open surgery (OR=3.681) and neoadjuvant radiotherapy (OR=2.495) were the risk factors of chest pain.ConclusionThere are many symptoms in patients with esophageal cancer after operation, and the occurrence of symptoms is closely related to gender, age, tumor location, surgical procedure and neoadjuvant chemoradiotherapy.
目的 利用磁共振彌散張量成像技術（DTI）對右側難治性顳葉癲癇（TLE）患者術前及術后腦白質各向異性分數（FA）進行縱向隨訪研究，并對其與病程等臨床癥狀之間的相關性進行分析，探討右側TLE患者的腦白質FA變化模式。 方法 2008年7月－2009年8月納入10例右側難治性TLE患者。對每個受試者采用GE 3.0 T磁共振及8通道頭線圈掃描，所有DTI圖像通過單次回波平面成像序列采集。采用基于體素分析的SPM8軟件對受試患者術前術后FA圖進行配對t檢驗，觀察難治性TLE患者腦白質變化模式。采用Pearson相關計算FA變化幅度與病程等臨床癥狀之間的相關性，經比較校正后P值＜0.05的區域為有統計學意義的區域。 結果 右側TLE患者FA值降低的區域包括左側顳下回、雙側額中回及左側殼核、右側楔葉。FA升高的區域包括左側海馬旁回、左側顳葉、右側額下回和左側中央旁小葉。相關分析發現，右側TLE患者右側額下回FA變化值與發病年齡呈負相關，左側顳下回FA變化值與術后隨訪間隔時間呈負相關。 結論 右側難治性TLE患者手術治療后大腦白質變化不僅局限于顳葉，還涉及顳葉外結構。