ObjectiveTo investigate the influencing factors of umbilical cord blood collection volume in newborns with congenital heart disease (CHD), so as to provide a scientific basis for promoting the development of umbilical cord blood reinfusion technology. MethodsA retrospective study was conducted on CHD newborns who were delivered in the Department of Obstetrics, Guangdong Provincial People's Hospital and underwent umbilical cord blood collection from August 2024 to January 2026. Clinical data related to pregnant women, newborns, placentas and umbilical cords were collected. ResultsA total of 144 CHD newborns were enrolled, including 50 in the simple CHD group and 94 in the complex CHD group. The mean maternal age was (31.0±5.0) years. Among the CHD newborns, 96 (66.7%) were male and 48 (33.3%) were female. Umbilical cord blood collection volume was significantly positively correlated with maternal weight, placental weight, umbilical cord length, neonatal body length, neonatal head circumference and birth weight, among which neonatal head circumference (r=0.315, P<0.001) and birth weight (r=0.327, P<0.001) showed the strongest correlations. Multiple linear regression analysis revealed that after adjusting for neonatal birth weight, placental weight, umbilical cord length and maternal weight, only umbilical cord length was an independent influencing factor for umbilical cord blood collection volume (B=0.488, β=0.262, P=0.007). ConclusionThe volume of umbilical cord blood collected from CHD newborns is affected by multiple factors, among which umbilical cord length is the most dominant one.
Scoping reviews are intended to help researchers in complex and extensive fields can better address exploratory research questions, comprehensive and systematic understanding of the current development of a field. However, the current scoping review needs to be unified in the implementation process, and the emergence of the JBI scoping review execution process can solve this problem well, which combines and improves the framework of the previous execution process, and regulates the whole process of scoping review production in depth and comprehensively from the aspects of the research purpose and questions, inclusion criteria, search, screening, data extraction, and analysis of the results, etc., and it has a strong authority and professionalism. Therefore, in order to help researchers better carry out and implement the scoping reviews, this paper focuses on the JBI scoping review execution process, and through detailed interpretation of the JBI scoping review execution process and demonstration of examples, it provides references for researchers to correctly apply the JBI scoping review execution process, in order to enhance the transparency and reliability of the research results, and to promote the scientific application of scoping reviews in China.
Meta-research is the "research of research", which aims to explore the existing quality of research in the scientific field, so as to help researchers comprehensively and systematically understand the current status of research development in a certain field, and to find relevant solutions to improve the quality of research in the field, which is a kind of scientific research concept. The concept of meta-research is widely used in the field of medicine, but its definition and use are still unclear in China. Therefore, this paper explores the origin of the definition of meta-research, the scope of research areas involved, and the path of its translation and implementation from the medical perspective, to help domestic researchers understand and familiarize themselves with the theoretical basis of meta-research, and provide them with a framework of ideas for the correct conduct and implementation of meta-research, so as to promote the scientific application and development of meta-research in the domestic medical field.