目的 分析眼表面腫塊的發病情況及組織病理學特點。 方法 對2004年1月-2008年12月收治并經病理學證實的326例眼表面腫塊患者的年齡、性別、眼別、腫塊發生部位、腫塊性質及病理類型進行回顧性分析。 結果 326例眼表面腫塊中，良性腫塊264例（81.0%），惡性腫塊62例（19.0%）。良性腫塊中，前5位分別為色素痣67例（25.4）%，迷芽瘤63例（23.9）%，乳頭狀瘤39例（占14.8）%，結膜囊腫25例（9.5）%，炎性肉芽腫20例（7.6）%。惡性腫塊中，前4位分別為鱗狀細胞癌25例（40.3）%，淋巴瘤13例（21.0）%，惡性黑色素瘤12例（19.4）%，原位癌10例（16.1）%。 結論 眼球表面的腫塊有共同的組織細胞起源，腫塊的亞型表現出不同的組織結構、良惡性和好發部位；而同部位的良性、交界性和惡性病變的衍變發展，從某種程度上體現了一個疾病的不同發展階段，三者間的鑒別和明確的病理診斷能為臨床選擇手術時機及手術方式提供依據。
ObjectiveTo assess the outcomes of laparoscopy-assisted surgery for treatment of advanced gastric cancer.MethodsA total of 115 patients with advanced gastric cancer were included between January 2014 and December 2018 were analyzed retroprospectively, the patients were divided into two groups: open surgery group (OS group, n=63) and laparoscopy-assisted surgery group (LAS group, n=52). Baseline characteristics, intraoperative parameters and postoperative items, and long-term efficacy were compared between the two groups.ResultsThere was no significant difference in preoperative baseline data including gender, age and preoperative serum parameters between the two groups (P>0.05). Intraoperative blood loss in the LAS group was significantly less than that in the OS group (P<0.05). In addition, the first feeding time after operation and postoperative hospital stay in the LAS group were significantly shorter than the OS group (P<0.05). Furthermore, numbers of white blood cells and neutrophils in the LAS group were fewer than that in the OS group at postoperative 2 days (P<0.05); the level of serum albumin in the LAS group was higher than that OS group (P<0.05). The number of lymph nodes detected during operation in the LAS group was more than that in the OS group (P<0.05). Operative time and occurrence of postoperative complications were not statistically significant between the two groups (P>0.05). One hundred and ten of 115 patients were followed- up, the follow-up rate was 95.7%. The follow-up time ranged from 6 to 48 months, with a median follow-up time of 12.4 months. The disease-free survival time of the OS group was 12.2±6.5 months, while that of the LAS group was 13.5±7.4 months. There was no significant difference between the two groups (P>0.05).ConclusionsLaparoscopic technique in treatment of advanced gastric cancer has the minimally invasive advantage, less intraoperative blood loss, less surgical trauma, and faster postoperative recovery in comparing to the traditional open surgery. Also the lymph node dissection is superior to open surgery. The curative effect is comparable to that of open surgery.