ObjectiveTo investigate the relation between histology type and prognosis of gastric cancer.MethodsThe clinical database of 311 patients who underwent surgical resection for gastric cancer in our hospital, between 2000 and 2004, was retrospectively reviewed and analyzed with SPSS 13.0. ResultsLymph node metastasis, tumor invasion depth, and Borrman type of gastric cancer were related with histology type （χ2 test, Plt;0.05）. KaplanMeier survival analysis was used to compare the survival rate and showed that there was a significant difference between highly/moderately differentiated cancers and the poorly differentiated (Plt;0.05), while there was no statistical difference between those patients with same invasion depth （Pgt;0.05）. ConclusionThe prognosis of gastric cancers with same invasion depth is same regardless of their histology types.