目的 探討高齡初產婦臨產前的心理狀態,了解其負性心理原因,及時給予護理干預,使其順利渡過圍生期。 方法 2010年6月-2011年9月,將在待產且年齡≥35歲的60例初產婦歸為高齡組,隨機選取同期住院的適齡初產婦60例作為對照組,應用焦慮自評量表(SAS)、抑郁自評量表(SDS)及癥狀自評量表(SCL-90),對高齡初產婦進行產前心理評估及檢測血中腎上腺素(E)和去甲腎上腺素(NE)水平。 結果 高齡初產婦產前的SAS和SDS評分及E和NE水平,SCL-90量表中總分及軀體化、強迫、焦慮、抑郁因子分與適齡組比較,差異有統計學意義(P<0.01);SAS評分與E、NE水平,SDS評分與E、NE水平均呈正相關,相關系數分別為:0.378、0.402、0.384、0.369(P<0.01)。 結論 高齡初產婦分娩前多數存在不同程度的負性心理,應根據其不同情況給予相應的心理干預以促進產婦順利渡過圍生期。
Objective To analysis and explore the value of metagenomics next-generation sequencing (mNGS) and clinical characteristics of Chlamydia psittaci (C. psittaci) pneumonia. Methods Totally 5 patients who were diagnosed with C. psittaci pneumonia and were treated in the Department of Respiratory and Critical Care Medicine and the Department of Infectious Diseases of Huazhong University of Science and Technology Union Shenzhen Hospital from Febuary 2021 to March 2021 were enrolled in the study. The clinical data of the patients were analyzed, and the clinical characteristics of the disease and treatment experience were summarized. Results The main symptoms of the 5 patients were high fever and cough, 4 of them had a history of raising parrots. The white blood cell and the neutrophils were mostly normal or slightly increased, the C reactive protein and erythrocyte sedimentation rate were significantly increased. The chest CT showed exudation and consolidation of one or several lung lobes. The serious patients might develop respiratory failure, if they were not treated by effective antibiotics. The diagnosis was based on clinical manifestations, contact history and alveolar lavage fluid that were detected by mNGS technology of C. psittaci nucleic acid sequence. The accuracy of detecting pathogens in alveolar lavage fluid by mNGS was high. In addition, mNGS could also identify other bacteria or viruses. After the timely adjustment of treatment, the condition of the patients was improved relied on tetracycline drugs or quinolone drugs, which shortened the diagnosis time and course of C. psittaci pneumnonia and reduced the use of unnecessary antibacterial drugs. Conclusions mNGS is of great significance in diagnosing C. psittaci pneumonia. The timely use of appropriate antibacterial drugs can achieve favorable therapeutic effect.