目的 探討縫合治療在膝關節內側半月板桶柄狀撕裂中的應用及效果。 方法 對2010年6月－2012年7月18例膝關節內側半月板桶柄狀撕裂患者，采用多種縫合材料、縫合方式相結合的方法予以救治。 結果 18例患者術后即時MRI均顯示內側半月板位置、形態恢復良好。隨訪12～26個月，所有患者膝關節活動度均正常，Lysholm評分術前（45.0 ± 3.5）分，術后末次隨訪（93.0 ± 5.1）分，差異有統計學意義（t=2.064，P＜0.05）；國際膝關節文獻委員會膝關節評估表評分，術前（49.0 ± 1.5）分，術后（92.0 ± 3.6）分，差異有統計學意義（t=2.205，P＜0.05）；無膝關節疼痛，麥氏試驗陰性，術后MRI顯示內側半月板愈合良好。 結論 采用縫合方法可挽救內側半月板桶柄狀撕裂，恢復半月板穩定性及正常功能。
Objective To observe the growth of orthotopic transplanted tumor in nude mice after stomatin-like protein 2 (SLP-2) expression decreased, and to further study the role of SLP-2 in the development and progression of esophageal squamous cell carcinoma. Methods Using RNA interference technique, esophageal squamous cell carcinoma cell lines with specific expression of SLP-2 and stable expression of luciferase were established. The healthy female nude mice with weight ranging from 19 to 22 g were randomly divided into 3 groups (n=12), 6 mice were used to establish subcutaneous xenografts, and the other 6 mice were used to establish the orthotopic transplanted tumor model (Group 1: cell infected with SLP-2-1 plasmid; group 2: cell infected with SLP-2-2 plasmid; group 3: cell infected with SHGFP plasmid). Index of the experiment end was weight loss and poor general situation in any mouse. Before the nude mice were sacrificed, the luciferase value of the tumor was detected by using in vivo imaging technique. After the nude mice were sacrificed, the primary tumor was removed for pathology examination. Results There was no significant difference in region of interest (ROI) value between the group 1 and group 2 (P=0.943). The ROI value for both groups 1 and 2 was significantly lower than that in the group 3 (P=0.002, P=0.000). The primary tumor infiltrated into the muscularis propria of esophageal was observed in all groups. Conclusion SLP-2 is involved in the development and progression of esophageal squamous cell carcinoma, and the decrease of SLP-2 expression can inhibit the growth of esophageal squamous cell carcinoma.