In recent years, the rapid development of information and communication technology, big data, and artificial intelligence has provided technical support for exploring new medical methods, leading to the emergence of digital therapeutics (DTx). At present, the application of DTx in orthopedics is still in the preliminary exploration stage. Therefore, based on the authors’ experience of applying DTx, this article summarizes the definition and formation process of DTx, as well as the relationship among digital health, digital medicine, and DTx, evaluates the working principles and application effects of existing orthopedic related DTx products, analyzes their shortcomings in the application process, and looks forward to their future development trends, aiming to lay a foundation for the comprehensive development and application of DTx in orthopedics.