Backgroud Chronic hepatitis is the major infectious disease of liver. There is no effective drug for it up to now. Clinical trials have showed that glycyrrhizin have potentional effective for chronic hepatitis. Objective To evaluate the effectiveness, safety and economics of glycyrrhizin for chronic hepatitis B and C. Search strategy The search terms include glycyrrhizin and its products’ name, chronic hepatitis and chronic carrier status. The thais registers of the Cochrane Hepato-Biliary Group, the Cochrane Complementary Medicine Field, and the central database of The Cochrane Library as well as MEDLINE, EMBASE and Chinese Biomedical CD Database were searched from their date of inception onward. And the free Internet search was operated to find ongoing and unpublished researches. Twenty Chinese medical journals and relevant academic conference proceedings have been searched by manual method. The reference lists of identified documents were checked as the complementary search. Inclusion criteria All randomized trials that tested glycryyhizin for chronic hepatitis B virus or hepatitis C virus infection were included in this review. Method of the review According to the principle of Cochrane systematic review, selection of thai for inclusion, assessment of methodological quality, data extraction and data syntheses were conducted by two reviewers.
ObjectiveTo analyze the results and diagnostic value of postoperative chylous test of pleural effusion and to verify the clinicopathological factors affecting the results of chylous test.MethodsThe clinical data of 265 consecutive patients undergoing selective surgery at the Department of Thoracic Surgery, Shangjin Nanfu Hospital between May and August 2020 were retrospectively analyzed, including 106 males and 159 females with an average age of 53.0±12.2 years. According to the results of the chylous test on the operation day and postoperative first and second days, the patients were divided into two subgroups, including a positive group and a negative group, and the clinical data of the two groups were compared. Sensitivity and specificity of the chylous test were calculated. The influencing factors for chylous test were analyzed by multiple logistic regression analysis.ResultsThe positive rate of chylous test was 91.7%, 95.8% and 87.9% on the operation day and postoperative first and second days, respectively. There was no statistical difference in age, sex, surgical type, surgical approach, surgical site, surgical time, degree of lymph node dissection, treatment of thoracic duct, 24 hours pleural fluid drainage or 24 hours protein and fat food intake between the positive group and the negative group (P>0.05). The diagnostic sensitivity and specificity of the chylous experiment were 100.0% and 4.0%, respectively. Multiple logistic regression analysis showed that the surgical site (left/right chest) might be an influencing factor for the results of the chylous test (P=0.043, OR=0.458, 95%CI 0.216-0.974).ConclusionThe positive rate of chylous test of pleural effusion after thoracic surgery is very high. The chylous test produces a high misdiagnosis rate of chylothorax. The surgical site (left/right chest) may be an influencing factor for chylous test. The positive result of chylous test is not recommended as the direct diagnostic basis for postoperative chylothorax and guidance of the subsequent treatment.
Ablation therapy for pulmonary nodules is increasingly utilized as a crucial minimally invasive intervention for early lung cancer, yet a unified standard for its perioperative nursing care remains elusive. This review systematically synthesizes the essential aspects and recent advancements in perioperative nursing for pulmonary nodule ablation, aiming to provide evidence-based guidance for clinical practice. Through a comprehensive literature review from January 2023 to April 2026 across databases including CNKI, Wanfang, VIP, and PubMed, we identify that optimal perioperative nursing should integrate across the entire patient management continuum: preoperative care emphasizes comprehensive assessment, psychological counseling, and breathing and breath-holding training; intraoperative care focuses on environment and equipment preparation, patient positioning, vital sign monitoring, operational assistance, and emergency response; and postoperative care is centered on vigilant condition observation, meticulous management of common complications such as pneumothorax, hemorrhage, pain, and fever (with particular attention to skin frostbite in cryoablation), health education, and stratified follow-up. Differences in nursing considerations for various ablation modalities, including radiofrequency, microwave, and cryoablation, are also discussed. Evidence suggests that implementing standardized and holistic perioperative nursing significantly reduces complication risks, enhances patient recovery, and is vital for ensuring the safety and efficacy of ablation therapy. Future improvements should actively incorporate information-based follow-up, artificial intelligence for risk assessment, and multidisciplinary collaboration models to further elevate nursing quality and improve long-term patient prognoses.
ObjectiveTo summarize and analyze the standardized operational procedure and preliminary clinical outcomes of a "three-dimensional integrated" respiratory training model, and to propose a safe adjunctive intervention for the perioperative management of lung nodule ablation. MethodsClinical data from patients who underwent lung nodule ablation at West China Hospital, Sichuan University from August to December 2025 were consecutively enrolled and analyzed. Results A total of 18 patients were included, comprising 10 males and 8 females, with a mean age of (62.8±11.2) years. Following the implementation of the preoperative "three-dimensional integrated" respiratory training model, the mean breath-holding time significantly increased from (22.9±7.5) s at admission to (32.6±6.9) s preoperatively (P<0.01). The volume measured on the respiratory trainer improved from a mean of(1 247.2±518.9) mL at admission to (1 550.0±546.1) mL preoperatively (P<0.01). Ablation modalities included radiofrequency ablation in 17 (94.4%) patients and cryoablation in 1 (5.6%) patient. During the ablation procedure, the mean number of needle adjustments was (1.4±0.8) times, and the mean localization time was (15.6±4.4) min. All patients successfully completed the ablation therapy, achieving a technical success rate of 100.0% with no intraoperative complications. ConclusionThe "three-dimensional integrated" respiratory training model effectively enhances patients' surgical tolerance, cooperation, and procedural precision. It offers a new, safe, and effective perioperative management strategy, especially for high-risk patients (e.g., the elderly or those with poor lung function) who may be unable to tolerate conventional surgery. This model demonstrates promising potential for widespread clinical application.