Total hip arthroplasty (THA) is the mainstay of treatment for advanced hip arthritis, but a number of postoperative wound complications may occur, such as wound dehiscence, bleeding and infection. Among them, wound infection is one of the serious complications after THA, which may lead to hip dysfunction or even disability, prolong hospital stay, increase readmission rate and significantly increase related medical expenses. Therefore, further understanding and action to change modifiable risk factors associated with wound infection will not only reduce medical expenses, but also improve the prevention, treatment and care. This article reviews the risk factors of surgical wound infection over the past 5 years, including patients factors (serum albumin, serum transferrin, blood transfusion, congestive heart failure, diabetes, overweight or obesity, smoking, and long-term use of hormone) and medical factors (previous surgery, surgical approach, length of surgery, and operating room environment).