Immunopatbological characteristics of bovine serum albumin (BSA)-induced uveitis in rabbit was studied dynamically by enzyme bistochemical and immunohistoehemieal methods.The acid alpha;-naphthy acetate esterase(ANAE) positive cells in eboroid were found 7 days after intravenous injection of BSA. Then the number of the positive cells increased progressively and the retinal tissue was destroyed. Infihrated lymphocytes in ehoroidea were mostly positive ANAE cells when ehtssic granulomatous pathological change showed in retinae after 11 days. These results indicated that T lymphocyte may play an important role in patbologlc process of BSA-induced uveitis in rabbits and may be closely related to destruction of retinal tissue and formation of granulomas. Chin J Ocul Fundus Dis,1994,10:153-155）
Objective To explore the frequency, clinical features, and characteristics of results of fundus fluorescein angiography (FFA) of uveitis related cystoid macular edema (CME). Methods The clinical data and FFA results of 67 patients (106 eyes) with posterior uveitis examined in our hospital from July 2002 to June 2005 were collected. The clinical features and characteristics of FFA images of CME were observed and analyzed. Results Among the106 eyes of 67 patients with uveitis,the CME was observed in 28 eyes (26.4%) of 18 patients, including 7 males and 11 females with the average age of (42.5plusmn;10.8) years. The dark area due to the choroidal fluorescence blocked by the macular edema was found at the early FFA phase, and th en followed by the punctate and sheetlike leakage of fluorescein; the capillar y was dilated at the venous phase, and the typical petaloid appearance was seen at the late phase because the fluorescein cumulated in several small vesicles in the macular area. After treated by corticosteroids and topical non-steroidal anti-inflammatory medicine and carbonic anhydrase inhibitors, the extent of CME diminished, and the visual acuity improved in varying degrees. Conclusi ons Uveitis may seriously harm the visual function, in which CME induces the damage of visual acuity. Early detection and timely treatment may prevent thepermanent visual damage. (Chin J Ocul Fundus Dis, 2006, 22: 394-396)