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碘131治療兒童甲狀腺乳頭狀癌伴頸部淋巴結轉移的護理一例

甲狀腺功能亢進碘131治療后遲發性放射性甲狀腺炎的治療護理一例

Diagnostic Value of Serum Thyroglobulin, Diagnostic 131I Whole-body Scan and Neck Ultrasonography for Evaluation of Lymph Node Metastasis and Recurrence of Differentiated Thyroid Cancer

ObjectiveTo compare the diagnostic efficacy of serum thyroglobulin (Tg), diagnostic 131I whole-body scan (D-WBS), neck ultrasound for diagnosing metastasis and recurrence of differentiated thyroid carcinoma (DTC). MethodsFrom May to June 2011, fifty follow-up DTC patients were collected retrospectively 6 months or more after 131I ablation therapy following total-thyroidectomy or near-total thyroidectomy. The diagnostic standard for DTC metastasis and relapse were based on serum Tg, D-WBS, neck ultrasound and chest CT. Diagnostic 2 by 2 table was employed for calculating the sensitivity, specificity, accuracy of the methods. ResultsThe sensitivity, specificity, accuracy, positive predictive value, negative predictive value of TgIMA and D-WBS parallel experiments were 100.0%, 92.9%, 96.0%, 91.7%, and 100.0% respectively. ConclusionTgIMA combined with D-WBS parallel test in diagnosis of DTC metastasis and recurrence has the highest accuracy.

分化型甲狀腺癌患者術后碘131治療的不良反應護理

目的 總結核醫學科分化型甲狀腺癌術后患者口服碘131（131I）治療的常見不良反應及處理。 方法 收集2013年7月－2014年6月經131I治療的分化型甲狀腺癌術后患者970例，總結131I治療過程中出現的不良反應，以及針對各種不良反應給予的相應處理措施。 結果 970例分化型甲狀腺癌術后患者均順利出院，502例出現不良反應，不良反應發生率為5 1.75%。其中頭頸部反應258例，消化道反應398例，造血系統反應2例，生殖系統反應1例。在發生不良反應的502例患者中，401例患者出現的不良反應在其出院時均得到有效緩解，53例患者在出院1個月后電話隨訪中告知不良反應已消失，48例訴癥狀已逐漸減輕。 結論 131I治療分化型甲狀腺癌可出現一過性的不良反應。對癥處理后均可恢復正常。