【摘要】 目的 探討CT引導下經椎弓根穿刺活檢對椎體病變的診斷價值及可行性。 方法 回顧性分析2009年5月—2010年4月42例椎體病變患者經椎弓根穿刺活檢的穿刺活檢方法、病理結果、最終診斷及穿刺并發癥。 結果 患者總穿刺準確率為95.2%（40/42）。其中惡性病變的穿刺準確率為94.3%（33/35），良性病變穿刺準確率為100%（7/7）；所有患者均未發生嚴重穿刺并發癥。 結論 CT引導下經椎弓根穿刺活檢診斷椎體病變有安全可靠、準確性高等特點。【Abstract】 Objective To explore the value and the feasibility of CT guided transpedicular biopsy in diagnosing vertebral body lesions. Methods From May 2009 to April 2010, 42 patients with vertebral body lesions underwent CT guided transpedicular biopsy. The clinical data including the puncture method, pahtological resutls, final diagnosis, and the pucture complications were retrospectively analyzed. Results The total accuracy rate of the puncture was 95.2%(40/42). The accuracy rate of the puncture was 94.3% (33/35) for malignant lesions and 100.0% (7/7) for benign lesions. No complication occurred. Conclusion CT guided transpedicular biopsy is very helpful in diagnosing vertebral body lesions with high accuracy and fewer complications.
目的:探討經肝動脈導管注射明膠海綿碘化油乳劑治療肝癌合并嚴重動靜脈瘺的可行性及臨床應用價值。方法:對38例肝癌動靜脈瘺患者血管分別行超選擇插管注射明膠海綿碘化油乳劑,造影觀察動靜脈瘺的栓塞率,血管再通率,副作用,并發癥及生存率等指標。結果:38例肝癌動靜脈瘺患者經肝動脈導管注入明膠海綿碘化油乳劑約2~10mL栓塞,栓塞后造影顯示閉塞率為94.7%(36/38),4周后造影顯示動靜脈瘺再通率為5.56%(2/36),未見確切不良反應,腫瘤碘化油乳劑沉積好,患者6月生存率為94.7%(36/38),12月生存率為60.5%(23/38),24月生存率為21.1%(8/38)。結論:經肝動脈導管注射碘化油乳劑治療肝癌動靜脈瘺安全可靠,對瘺口要求不高,栓塞率高,再通率低,腫瘤的栓塞治療效果好。
Objective To investigate the feasibil ity, safety and operative techniques of percutaneous vertebroplasty (PVP) in treating osteolytic bone metastasis of cervical vertebra and reconstructing the function of cervical vertebra. Methods From March 2005 to December 2007, 10 patients with osteolytic bone metastatic carcinoma in single cervical vertebral body received PVP, including 5 males and 5 females aged 38-75 years (mean 54.5 years). Among them, 5 patients had primary lung tumor, 1 primary renal tumor, 1 primary breast tumor, 1 primary cervical tumor and 2 unknown primary lesion. The course of disease was 2-4 years. All the patients suffered from obviously cervical pain and l imitation of activity, including 4 cases of metastatic tumor of the C2 vertebral body, 2 of C3, 2 of C6 and 2 of C7. The general condition of patients was stable before operation, and no blood coagulation dysfunction, radiculalgia and spinal cord compression were detected. Lateral PVP was performed on 6 cases, approaching between the vertebral artery and the carotid sheath under CT guidance and anterolateral PVP was performed on the rest 4 cases, approaching between the trachea and the internal carotid artery under continuously X-ray fluoroscopy. The amount of bone cement injected was 3-4 mL, and the fill ing rate was 50%-100%. Results Without obvious bleeding or organ injury, the puncture was performed successfully on all the patients. Without symptom of spinal cord compression, patients suffered from pain during operation (1 case) and such compl ications noted by immediate CT or X-rays examination after operation as paravertebral epidural cement leakage (2 ases),transverse foramen cement leakage (1 case) and pinhole reflux (3 cases). The pain of patients was improved to various degree postoperatively, the visual analogue scales score was (5.9 ± 1.2) points before operation, which was changed to (2.6 ± 1.2) points at 1 hour after PVP and (1.6 ± 1.3) points at 1 week after PVP, indicating there was a significant difference between pre- and postoperation (P lt; 0.05). During the regular follow-up at 1 week, 3 and 12 months after PVP, all patients had no dislocation of cervical vertebra body, spinal cord compression and paralysis. Five patients died from multiple organ failure due to primary tumor progression, including 3 cases at 6 months after PVP and 2 at 12 months after PVP, and the rest 5 patients’ cervical pain were under control, with sound functional recovery. Conclusion PVP can rel ieve pain quickly and reinforce the stabil ity of the vertebral body, and has sl ight compl ications; the lateral approach is safe and effective.