目的 總結原發性腹膜后脂肪肉瘤（primary retroperitoneal liposarcoma，PRL）的臨床病理特征、診斷及治療方法。 方法 回顧性分析經手術和活檢證實的23例PRL患者的臨床病理資料。結果 首發癥狀及體征表現為腹部腫塊（91.3%，21/23），腹脹（56.5%，13/23）及腹痛（30.4%，7/23）。B超及CT的定位診斷準確率分別為66.7%（12/18）和85.7%（12/14）。首次手術腫瘤完整切除16例（69.6%），其中8例聯合臟器切除； 部分切除3例（13.0%）； 僅行活檢4例（17.4%）。PRL腫瘤完整切除術后復發率為75.0%（12/16）,該12例中再次手術8例（66.7%）可完全切除腫瘤。結論 CT是診斷PRL的重要手段，優于B超； 手術以完整切除腫瘤為主，對侵犯臟器者采用累及臟器一并切除； 術后復發者可再次手術。
ObjectiveTo evaluate the risk factors for central lymph node metastasis (CLNM) in papillary thyroid carcinoma (PTC) of cN0 staging. MethodsClinical data of 94 patients with cN0 PTC in Guangdong General Hospital who underwent thyroidectomy with prophylactic central node dissection (pCND) from March to July in 2014 were collected to analyze the risk factors of CLNM by using univariate and multivariate analysis methods. ResultsCLNM was found in 43 patients (45.7%). Multivariate analysis results showed that, the CLNM rate of patients with age < 45 years, tumor located in front of lobe by ultrasound, diameter of tumor > 2 cm, capsular invasion, and total number of central lymph node dissected > 3 were significantly higher (P < 0.05). ConclusionAge < 45 years, tumor located in front of lobe by ultrasound, and diameter of tumor > 2 cm are the risk factors of CLNM in patients with cN0 PTC, pCND should be performed for patients with some of the above risk factors.