目的觀察腔內激光聯合聚桂醇泡沫硬化劑治療下肢靜脈曲張的臨床效果。 方法回顧性分析2009年2月至2013年7月期間接受腔內激光聯合聚桂醇泡沫硬化劑治療的40例下肢靜脈曲張患者(聯合組)和單純接受腔內激光治療的40例下肢靜脈曲張患者(對照組)的臨床資料,比較2種治療方法的效果。 結果聯合組和對照組患者的手術時間〔(43.95±6.77)min比(45.20±6.77)min〕和術中出血量〔(16.07±4.30)mL比(16.65±4.50)mL〕比較差異均無統計學意義(P>0.05),但聯合組的手術費用低于對照組〔(7 056.83±940.45)元比(7 473.81±1 476.09)元〕,P=0.044。術后對照組的并發癥發生率為20.0%(8/40),高于聯合組的5.0%(1/40),差異有統計學意義(P=0.029)。術后所有患者獲訪4~24個月、(15.5±6.7)個月。隨訪期間,80例患者的下肢曲張畸形靜脈均消失,對照組小范圍復發3例(7.5%),聯合組小范圍復發2例(5.0%),2組復發率的差異無統計學意義(P=1.000)。 結論對下肢靜脈曲張,腔內激光聯合泡沫硬化劑治療是一種安全和有效的新微創手術方法,具有并發癥發生率低的優點,值得臨床推廣。
To standardize the treatment of secondary hyperparathyroidism and effectively meet the needs of practical clinical work, we gathered experts and nursing experts from Departments of Thyroid Surgery, Nephrology, Endocrinology and Metabolism, Nuclear Medicine, Ultrasound, Anesthesiology, Cardiology, and other departments at West China Hospital of Sichuan University to solicit opinions. This consensus was finally established based on published guidelines and the best evidence in Chinese and English combined with clinical practice. This consensus is intended to summarize and conclude, to the greatest extent possible, the practical issues encountered in diagnosing and treating secondary hyperparathyroidism in perioperative settings and to provide recommendations for clinical practice.