目的 探討腹腔鏡對小腸大出血的診斷和治療。方法 對15例懷疑小腸大出血的患者進行腹腔鏡探查。結果 探查陽性率100%，其中小腸腫瘤7例，小腸憩室5例，小腸憩室并套疊1例，小腸血管畸形2例，均在腹腔鏡輔助下行小腸部分切除或憩室切除術。結論 腹腔鏡對小腸出血的診斷尤其是治療方面有較高的價值。
Objective To compare the oncologic results between laparoscopic and open approach for the treatment of rectal cancer. Methods Five hundred and twenty patients with rectal cancer from Jan. 2003 to Dec. 2008 were non-randomly divided into laparoscopic (LS) and open surgery (OS) group. Local recurrence, distant metastasis and survival rate were compared between two groups. Results One hundred and eighty-six cases received laparoscopic resection and 334 cases received open operation. There were no statistically significant differences (SSD) of demographic data between two groups (Pgt;0.05). Mean follow-up was 30.3 months. No SSD was observed in 3-year cumulative survival rate (83% in LS and 80% in OS, P=0.549), distant metastasis rate (12.5% in LS and 15.6% in OS, P=0.368), incidence of incision seeding (0.6% in LS and 0 in OS, P=0.189), or cumulative survival (P=0.142). The differences of local recurrences rate (4.8% in LS and 10.7% in OS, P=0.028), 3-year cumulative disease-free survival rate (81% in LS and 68% in OS, P=0.009), and cumulative disease-free survival (P=0.010) between two groups were statistical significant. The differences of cumulative survival, cumulative disease-free survival, local recurrences， and distant metastasis according to the TNM stageⅠ or Ⅱ between two groups were not statistical significant. The differences of cumulative disease-free survival and local recurrences according to the TNM stage Ⅲ reached statistical significance (P=0.045 and P=0.047, respectively). Conclusion Oncologic results of laparoscopic resection are similar to those of open resection for rectal carcinoma．
【摘要】 目的 探討葡萄糖轉運蛋白Ⅰ型（glucose transporter 1，GLUT1）和腫瘤增殖細胞核抗原Ki-67在卵巢上皮性腫瘤組織中的表達及其臨床意義。 方法 收集2000年1月-2008年6月不同卵巢上皮性腫瘤病變患者119例的組織標本，采用免疫組織化學SP二步法檢測腫瘤組織中GLUT1和Ki-67的表達情況。 結果 卵巢交界性、惡性上皮性腫瘤灶性或廣泛高表達GLUT1和Ki-67，其表達強度有差異。卵巢良性上皮性腫瘤不表達GLUT1和Ki-67。在卵巢癌中GLUT1及Ki-67的表達強度與病理分級、臨床分期、預后有關。GLUT1表達強度與病理分型無關，Ki-67表達強度與病理分型有關。 結論 卵巢上皮性腫瘤組織中GLUT1和Ki-67的表達具有相關性，其表達強度與腫瘤的良惡性質和增殖狀態有關，二者同時檢測可以全面了解卵巢上皮性腫瘤的性質、卵巢癌惡性程度和生物學行為，對于判斷腫瘤的性質和預后有一定價值。【Abstract】 Objective To investigate the expression and clinical significance of glucose transporter-1 (GLUT1) and tumor proliferating karyon antigen Ki-67 in epithelial ovarian tumor tissue. Methods Immunohistochemistry SP method was used to detect the expression of GLUT1 and Ki-67 protein in epithelial ovarian tumor tissues from 119 patients diagnosed in our hospital from January 2000 to June 2008. Results The expressions of GLUT1 and Ki-67 had local or abroad higher expressions in the borderline and malignant epithelial ovarian tumor, and the expressive intensity was different. In benign tumors, the expression was negative. The expressive intensity of GLUT1 and Ki-67 had correlation with the grade, stage, and prognosis in malignant tumors. The expressive intensity of GLUT1 had no correlation with the type of malignant tumors, while Ki-67 related to the pathological types. Conclusion The expressions of GLUT1 and Ki-67 have relativity. The expressive intensity of GLUT1 and Ki-67 relates to the character and proliferation of epithelial ovarian tumors. The combined detection GLUT1 and Ki-67 is helpful to know the character of epithelial ovarian tumors, the malignant degree and biologic behavior of ovarian carcinoma, which is useful in estimating the character and prognosis of epithelial ovarian tumors.