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    find Keyword "二尖瓣" 252 results
    • Surgical Treatment of Partial Atrioventricular Canal Defect in 66 Cases

      Objective To summarize the experiences of surgical treatment for partial atrioventricular canal defect. Methods The data of 66 patients of surgical treatment for partial atrioventricular canal defect from January 1984 to December 2007 were analyzed retrospectively. The cleft of mitral valve presented in all of those patients. There were 52 cases with direct suture on cleft, 8 cases with direct suture with commissurroplasty, 1 case with posterior leaflet plasty, 3 cases with direct suture St.Jude ring and 2 cases mitral valve replacement. The ostium primum atrial septal defects were repaired with patches of Dacron in 12 cases and autologous pericardium in 54 cases. Coronary sinus was situated on the left atrium in 5 and ostium primum atrial septal defects were repaired in Kirklin’s way; the others in MeGoon’way. Meanwhile other heart abnormalities were done. Results There were two early deaths (3.03%), one patient died of heart arrhythmia and one patient died of respiratory failure. Complications of total A-V block was in 2 cases. Both of them were replanted with pace makers.52 cases were followed up, followup time was 5 months to 22 years(mean follow-up 15 years). All patients had better life. Four patients have been re -operated for different reasons post primary operation. One had good result after re-mitral valve replacement. One case died of acute renal failure and the other two died of low cardiac output syndrome. Conclusions Early operation is definitely recommended when the diagnosis is confirmed. Because the structure or function of mitral valve is saved, pulmonary hypertension is avoided and the mortality is lower in the future. The key points of operation are to rectify the mitral insufficiency, repair ostium primum atrial septal defects and avoid atrioventricular block. The patients of mild regurgitation of mitral valve have good results. Provided in those have more than middle regurgitation of mitral valve then their longterm results are poor.

      Release date:2016-08-30 06:05 Export PDF Favorites Scan
    • 保留后瓣及瓣下結構的二尖瓣置換術

      目的 總結保留后瓣及瓣下結構的二尖瓣置換術(MVR)的臨床經驗,并觀察其與常規MVR比較的臨床效果。方法 風濕性心瓣膜病患者54例,其中行保留后瓣及瓣下結構的MVR24例(保留二尖瓣后瓣組),行常規MVR30例(常規手術組),觀察兩組患者術前、術后3個月的左心室舒張期末內徑(LVEDD)、左心室射血分數(LVEF)、左心室短軸縮短率(LVFS)等指標。結果 保留二尖瓣后瓣組無死亡患者,常規手術組死亡1例;保留二尖瓣后瓣組術后血管活性藥物的用量、種類和呼吸機使用時間較常規手術組減少;術后3個月保留二尖瓣后瓣組LVEDD較常規手術組減小,LVEF較常規手術組增大(P〈0.05)。結論 保留后瓣及瓣下結構的MVR手術操作不復雜,不增加心內手術時間,有可能減少左心室破裂的危險,術中操作仔細可以避免卡瓣,術后心功能恢復較好,更適用于心功能較差、左心室較大的以二尖瓣關閉不全為主的患者。

      Release date:2016-08-30 06:26 Export PDF Favorites Scan
    • Clinical Outcomes and Predictive Factor Analysis of Mild-to-moderate or Moderate Functional Mitral Regurgitationafter Aortic Valve Replacement in Patients with Severe Aortic Stenosis

      Objective To evaluate clinical outcomes of mild-to-moderate or moderate functional mitral regurgitation(FMR)after aortic valve replacement (AVR) in patients with severe aortic stenosis (AS),and analyze prognostic factors of these patients with mild-to-moderate or moderate FMR (2+to 3+). Methods From September 2008 to December 2011,a total of 156 patients with severe AS (peak aortic gradient (PAG)≥50 mm Hg) as well as FMR (2+to 3+) underwent surgical treatment in Zhongshan Hospital. There were 95 male and 61 female patients with their average age of 59.2±10.5 years. Detailed perioperative clinical data were collected,and postoperative patients were followed up. The ratio of FMRpreoperative/FMR postoperative was calculated. Patient age,gender,body weight,history of hypertension,ventricular arrhythmia,atrial fibrillation (AF),left ventricular ejection fraction (LVEF),left ventricular end-diastolic diameter (LVEDD),left atrial diameter (LAD),pulmonary artery hypertension (PAH),PAG were assessed by logistic multivariate regression analysis. Results Six patients died postoperatively,including 4 patients with low cardiac output syndrome and 2 patients with refractory ventricular arrhythmia. Perioperative mortality was 3.8%. The average follow-up time was 20.3±8.5 months and follow-up rate was 85.3% (133/156). Eight patients died during follow-up,including 3 patients with heart failure,2 patients with ventricular arrhythmia,and 3 patients with anticoagulation-related cerebrovascular accident. Multivariate regression analysis showed that FMR preoperative/FMR postoperative ratio was not correlated with age≥55 years,male gender,body weight≥80 kg,LVEDD≥55 mm,LVEF≤50%,history of hypertension or ventricular arrhythmia. However,LAD≥50 mm,PAH≥50 mm Hg,PAG≤75 mm Hg and preoperative AF were negatively correlated with postoperative FMR improvement. Conclusions Risk factors including LAD≥50 mm,PAH≥50 mm Hg,PAG≤75 mm Hg and preoperative AF are negatively correlated with postoperative improvement of FMR (2+to 3+). Patients with severe AS and above risk factors should receive concomitant surgical treatment for their FMR during AVR,since preoperative FMR(2+to 3+)usually does not improve or even aggravate after AVR.

      Release date:2016-08-30 05:46 Export PDF Favorites Scan
    • 二尖瓣生物瓣置換術后并發格林-巴利綜合征一例

      Release date:2016-08-30 05:28 Export PDF Favorites Scan
    • 用自體心包行二尖瓣成形術

      目的 總結用自體心包行二尖瓣成形術的經驗. 方法 1998年3~6月對5例二尖瓣病變的患者用自體心包行二尖瓣直視成形術. 結果 本組無死亡,復查心臟超聲心動圖示無反流1例,有輕度反流4例(0.6~1.5cm2).術后隨訪6~9個月,結果滿意. 結論 應用自體心包行二尖瓣成形術有避免人工瓣環異物反應、減少感染機會、不需抗凝治療、能替代軟質人工瓣環、減少費用等優點,具有臨床應用價值.

      Release date:2016-08-30 06:35 Export PDF Favorites Scan
    • “瓣中瓣”法二尖瓣置換術21例

      目的 探討保留全部二尖瓣結構置換二尖瓣的方法,即“瓣中瓣”方法的應用。方法 2002年1月至2005年2月,對21例二尖瓣病變患者采用“瓣中瓣”方法行二尖瓣置換術,術中保留全部二尖瓣結構,維持自然瓣下結構形態與位置,均采用2-0Prolene線進行連續縫合,將人工瓣膜置于二尖瓣口中央,同期行三尖瓣成形術15例。結果 全組均植入人工機械二尖瓣膜20枚和生物二尖瓣1枚,三尖瓣機械瓣2枚。主動脈阻斷時間平均17.1min,體外循環時間平均38.1min。手術及體外循環停機順利,無1例住院死亡和嚴重并發癥發生。術后第7d,左心室舒張期末內徑由76.1mm下降至60.1mm,左心房舒張期末內徑由67mm下降至49ram,心胸比率由0.72下降至0.56,射血分數由0.47增至0.59。結論 采用“瓣中瓣”方法置換二尖瓣,保持了二尖瓣下裝置的自然位置,操作簡便,有利于對心肌的保護,并減少術后并發癥的發生。

      Release date:2016-08-30 06:18 Export PDF Favorites Scan
    • 保留二尖瓣裝置的二尖瓣置換術

      目的 比較傳統二尖瓣置換術 (MVR)和保留二尖瓣裝置的 MVR治療單純風濕性二尖瓣狹窄的臨床效果。 方法 回顧性分析 77例單純風濕性二尖瓣狹窄行 MVR患者的臨床資料 ,按術式不同將其分為 3組 ,組 1:35例 ,保留全部二尖瓣裝置 ;組 2 :19例 ,保留二尖瓣后瓣瓣下結構 ;對照組 :2 3例 ,行傳統 MVR手術。 結果 術后早期對照組和組 1各死亡 1例 ,晚期對照組死亡 2例 ,組 1和組 2各死亡 1例。術后 3~ 16個月超聲心動圖檢查顯示 ,對照組和組 2左心室舒張期末內徑 (L VEDD)較術前明顯增大 (Plt;0 .0 1) ,組 1L VEDD增大不明顯 (Pgt;0 .0 1)。組 1、組 2左心室射血分數 (EF)和短軸縮短率 (FS)較術前有明顯改善 (Plt;0 .0 1) ,對照組改善不明顯 (Pgt;0 .0 1)。 結論 單純風濕性二尖瓣狹窄患者行 MVR時保留二尖瓣裝置有利于術后左心功能的恢復。

      Release date:2016-08-30 06:28 Export PDF Favorites Scan
    • Progress and prospect of robotic cardiac surgery

      Minimally invasive cardiac surgeries are the trend in the future. Among them, robotic cardiac surgery is the latest iteration with several key-hole incision, 3-dimentional visualization, and articulated instrumentation of 7 degree of ergonomic freedom for those complex procedures in the heart. In particular, robotic mitral valve surgery, as well as coronary artery bypass grafting, has evolved over the last decade and become the preferred method at certain specialized centers worldwide because of excellent results. Other cardiac procedures are in various stages of evolution. Stepwise innovation of robotic technology will continue to make robotic operations simpler, more efficient, and less invasive, which will encourage more surgeons to take up this technology and extend the benefits of robotic surgery to a larger patient population.

      Release date:2019-09-18 03:45 Export PDF Favorites Scan
    • 二尖瓣狹窄下游湍流剪應力與心瓣膜損害的關系

      目的 明確二尖瓣狹窄下游湍流剪應力(turbulent shear stress, TSS)與心瓣膜損害的關系,為在細胞水平研究TSS致心瓣膜內皮損傷提供前期研究. 方法 應用多普勒超聲心動圖與計算機圖像分析技術,以14例正常人為對照(對照組),對1998年1~4月在我院就診的47例二尖瓣狹窄患者(觀察組)心瓣膜病變及其下游TSS進行2年的隨訪動態觀測. 結果 觀察組隨訪期間心瓣膜病變與其下游TSS均呈明顯加重趨勢(P<0.05),且二者顯著相關(r =0.82,0.86);此外,TSS的大小和分布與心瓣膜不同部位病變的嚴重程度之間存在一定的空間對應關系.結論 二尖瓣狹窄下游所產生的湍流剪應力是構成患者心瓣膜病變進行性加重不容忽視的重要原因,其具體作用機制有待進一步研究加以闡明.

      Release date:2016-08-30 06:34 Export PDF Favorites Scan
    • Leaflet foldoplasty of mitral valvuloplasty for mitral regurgitation in children

      ObjectiveTo report the short-term outcomes of a standardized, simplified and reproducible strategy of mitral valvuloplasty (MVP), which was focused on leaflet foldoplasty and anatomic anomalies of congenital mitral regurgitation (MR).MethodsConsecutive 74 patients who underwent MVP by our standardized strategy in our institution from 2016 to 2018 were included retrospectively. There were 30 males and 44 females with a median age of 18.5 (6-146) months and weight of 15.4 (7-51) kg.ResultsAnatomic anomalies of MR included: (1) subvalvular apparatus: 72 (97.3%) patients with mal-connected chordae tendineae, 31 (41.9%) with absent chordae tendineae and 14 (18.9%) with fused or dysplastic papillary muscle; (2) leaflet: 10 (13.5%) patients with cleft of anterior leaflet, 61 (82.4%) with leaflet prolapse including 56 (91.8%) with anterior leaflet prolapse; (3) annulus: 71 (95.9%) patients with annular dilatation. Leaflet foldoplasty was performed in 61 (82.4%) patients with leaflet prolapse. All patients were successfully discharged and 4 (5.4%) patients were with moderate MR. The follow-up time was 22.0 (9.1-41.8) months. During the follow-up period, 3 patients had moderate MR and 1 patient had reoperation for severe MR. All patients were in normal cardiac function with a mean left ventricular ejection fraction of 66.0%±6.1%. In addition, the mean left ventricular end-diastolic dimension was 31.8±6.0 mm, which was significant smaller than that before the operation (t=6.090, P<0.000 1).ConclusionThe standardized leaflet foldoplasty with resection of mal-connected chordae tendineae and posterior annuloplasty technique is safe and feasible with favorable short-term outcomes in MR patients.

      Release date:2021-04-25 09:57 Export PDF Favorites Scan
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