Anticancer Therapy and Effectiveness Evaluation of Liver transplantation for Hepatocellular Carcinoma During Perioperative Period_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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楊廣順 , 趙文超

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肝移植; 肝癌; 輔助治療; 效果

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Citation： 楊廣順,趙文超. Anticancer Therapy and Effectiveness Evaluation of Liver transplantation for Hepatocellular Carcinoma During Perioperative Period. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2011, 18(4): 359-361. doi: Copy

1.	Tang ZY, Ye SL, Liu YK, et al. A decade’s studies on metastasis of hepatocellular carcinoma [J]. J Cancer Res Clin Oncol, 2004, 130(4): 187196.
2.	Yao FY, Bass NM, Nikolai B, et al. A followup analysis of the pattern and predictors of dropout from the waiting list for liver transplantation in patients with hepatocellular carcinoma: implications for the current organ allocation policy [J]. Liver Transpl, 2003, 9(7): 684692.
3.	Schreibman IR, Bejarano P, Martinez EJ, et al. Very late recurrence of hepatocellular carcinoma after liver transplantation: case report and literature review [J]. Transplant Proc, 2006, 38(9): 31403143.
4.	Majno P, Giostra E, Morel P; Geneva Liver Cancer Study Group. Management of hepatocellular carcinoma in the waiting list before liver transplantation [J]. J Hepatol, 2005, 42 Suppl(1): S134S143.
5.	Wong LL. Current status of liver transplantation for hepatocellular cancer [J]. Am J Surg, 2002, 183(3): 309316.
6.	Jang JW, You CR, Kim CW, et al. Benefit of downsizing hepatocellular carcinoma in a liver transplant population [J]. Aliment Pharmacol Ther, 2010, 31(3): 415423.
7.	Yao FY, Kinkhabwala M, LaBerge JM, et al. The impact of preoperative locoregional therapy on outcome after liver transplantation for hepatocellular carcinoma [J]. Am J Transplant, 2005, 5(4 Pt 1): 795804.
8.	Yao FY, Kerlan RK Jr, Hirose R, et al. Excellent outcome following downstaging of hepatocellular carcinoma prior to liver transplantation: an intentiontotreat analysis [J]. Hepatology, 2008, 48(3): 819827.
9.	Bharat A, Brown DB, Crippin JS, et al. Preliver transplantation locoregional adjuvant therapy for hepatocellular carcinoma as a strategy to improve longterm survival [J]. J Am Coll Surg, 2006, 203(4): 411420.
10.	Lencioni RA, Allgaier HP, Cioni D, et al. Small hepatocellular carcinoma in cirrhosis: randomized comparison of radiofrequency thermal ablation versus percutaneous ethanol injection [J]. Radiology, 2003, 228(1): 235240.
11.	Toso C, Mentha G, Kneteman NM, et al. The place of downstaging for hepatocellular carcinoma [J]. J Hepatol, 2010, 52(6): 930936.
12.	Ryu M, Shimamura Y, Kinoshita T, et al. Therapeutic results of resection, transcatheter arterial embolization and percutaneous transhepatic ethanol injection in 3 225 patients with hepatocellular carcinoma: a retrospective multicenter study [J]. Jpn J Clin Oncol, 1997, 27(4): 251257.
13.	Lin SM, Lin CJ, Lin CC, et al. Radiofrequency ablation improves prognosis compared with ethanol injection for hepatocellular carcinoma ≤4 cm [J]. Gastroenterology, 2004, 127(6): 17141723.
14.	Llovet JM, Real MI, Montaa X; Barcelona Liver Cancer Group. Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial [J]. Lancet, 2002, 359(9319): 17341739.
15.	Figueras J, Ibaez L, Ramos E, et al. Selection criteria for liver transplantation in earlystage hepatocellular carcinoma with cirrhosis: results of a multicenter study [J]. Liver Transpl, 2001, 7(10): 877883.
16.	Vivarelli M, Cucchetti A, Piscaglia F, et al. Analysis of risk factors for tumor recurrence after liver transplantation for hepatocellular carcinoma: key role of immunosuppression [J]. Liver Transpl, 2005, 11(5): 497503.
17.	Zhou J, Wang Z, Wu ZQ, et al. Sirolimusbased immunosuppression therapy in liver transplantation for patients with hepatocellular carcinoma exceeding the Milan criteria [J]. Transplant Proc, 2008, 40(10): 35483553.
18.	Olthoff KM. Surgical options for hepatocellular carcinoma: resection and transplantation [J]. Liver Transpl Surg, 1998, 4(5 Suppl 1): S98S104.
19.	Roayaie S, Frischer JS, Emre SH, et al. Longterm results with multimodal adjuvant therapy and liver transplantation for the treatment of hepatocellular carcinomas larger than 5 centimeters [J]. Ann Surg, 2002, 235(4): 533539.
20.	蘭竹, 陳知水, 曾凡軍, 等. 超出米蘭標準的原發性肝癌肝移植術后化療對患者存活和腫瘤復發率的影響 [J]. 中華器官移植雜志, 2006, 27(8): 481484.
21.	Samuel D, Muller R, Alexander G, et al. Liver transplantation in European patients with the hepatitis B surface antigen [J]. N Engl J Med, 1993, 329(25)： 18421847.

1. Tang ZY, Ye SL, Liu YK, et al. A decade’s studies on metastasis of hepatocellular carcinoma [J]. J Cancer Res Clin Oncol, 2004, 130(4): 187196.
2. Yao FY, Bass NM, Nikolai B, et al. A followup analysis of the pattern and predictors of dropout from the waiting list for liver transplantation in patients with hepatocellular carcinoma: implications for the current organ allocation policy [J]. Liver Transpl, 2003, 9(7): 684692.
3. Schreibman IR, Bejarano P, Martinez EJ, et al. Very late recurrence of hepatocellular carcinoma after liver transplantation: case report and literature review [J]. Transplant Proc, 2006, 38(9): 31403143.
4. Majno P, Giostra E, Morel P; Geneva Liver Cancer Study Group. Management of hepatocellular carcinoma in the waiting list before liver transplantation [J]. J Hepatol, 2005, 42 Suppl(1): S134S143.
5. Wong LL. Current status of liver transplantation for hepatocellular cancer [J]. Am J Surg, 2002, 183(3): 309316.
6. Jang JW, You CR, Kim CW, et al. Benefit of downsizing hepatocellular carcinoma in a liver transplant population [J]. Aliment Pharmacol Ther, 2010, 31(3): 415423.
7. Yao FY, Kinkhabwala M, LaBerge JM, et al. The impact of preoperative locoregional therapy on outcome after liver transplantation for hepatocellular carcinoma [J]. Am J Transplant, 2005, 5(4 Pt 1): 795804.
8. Yao FY, Kerlan RK Jr, Hirose R, et al. Excellent outcome following downstaging of hepatocellular carcinoma prior to liver transplantation: an intentiontotreat analysis [J]. Hepatology, 2008, 48(3): 819827.
9. Bharat A, Brown DB, Crippin JS, et al. Preliver transplantation locoregional adjuvant therapy for hepatocellular carcinoma as a strategy to improve longterm survival [J]. J Am Coll Surg, 2006, 203(4): 411420.
10. Lencioni RA, Allgaier HP, Cioni D, et al. Small hepatocellular carcinoma in cirrhosis: randomized comparison of radiofrequency thermal ablation versus percutaneous ethanol injection [J]. Radiology, 2003, 228(1): 235240.
11. Toso C, Mentha G, Kneteman NM, et al. The place of downstaging for hepatocellular carcinoma [J]. J Hepatol, 2010, 52(6): 930936.
12. Ryu M, Shimamura Y, Kinoshita T, et al. Therapeutic results of resection, transcatheter arterial embolization and percutaneous transhepatic ethanol injection in 3 225 patients with hepatocellular carcinoma: a retrospective multicenter study [J]. Jpn J Clin Oncol, 1997, 27(4): 251257.
13. Lin SM, Lin CJ, Lin CC, et al. Radiofrequency ablation improves prognosis compared with ethanol injection for hepatocellular carcinoma ≤4 cm [J]. Gastroenterology, 2004, 127(6): 17141723.
14. Llovet JM, Real MI, Montaa X; Barcelona Liver Cancer Group. Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial [J]. Lancet, 2002, 359(9319): 17341739.
15. Figueras J, Ibaez L, Ramos E, et al. Selection criteria for liver transplantation in earlystage hepatocellular carcinoma with cirrhosis: results of a multicenter study [J]. Liver Transpl, 2001, 7(10): 877883.
16. Vivarelli M, Cucchetti A, Piscaglia F, et al. Analysis of risk factors for tumor recurrence after liver transplantation for hepatocellular carcinoma: key role of immunosuppression [J]. Liver Transpl, 2005, 11(5): 497503.
17. Zhou J, Wang Z, Wu ZQ, et al. Sirolimusbased immunosuppression therapy in liver transplantation for patients with hepatocellular carcinoma exceeding the Milan criteria [J]. Transplant Proc, 2008, 40(10): 35483553.
18. Olthoff KM. Surgical options for hepatocellular carcinoma: resection and transplantation [J]. Liver Transpl Surg, 1998, 4(5 Suppl 1): S98S104.
19. Roayaie S, Frischer JS, Emre SH, et al. Longterm results with multimodal adjuvant therapy and liver transplantation for the treatment of hepatocellular carcinomas larger than 5 centimeters [J]. Ann Surg, 2002, 235(4): 533539.
20. 蘭竹, 陳知水, 曾凡軍, 等. 超出米蘭標準的原發性肝癌肝移植術后化療對患者存活和腫瘤復發率的影響 [J]. 中華器官移植雜志, 2006, 27(8): 481484.
21. Samuel D, Muller R, Alexander G, et al. Liver transplantation in European patients with the hepatitis B surface antigen [J]. N Engl J Med, 1993, 329(25)： 18421847.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Anticancer Therapy and Effectiveness Evaluation of Liver transplantation for Hepatocellular Carcinoma During Perioperative Period

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