• the Department of Orthopedics, Chengdu Railway Central Hospital, Chengdu 610081, China;
聚-DL -乳酸; 捆綁帶; 骨折固定; 生物力學polyDLlactic acid; cerclage band; fixation of fracture; biomechanics
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摘要:目的:研究生物降解聚DL乳酸(PDLLA)自鎖式捆綁帶固定骨折的生物力學性能。方法:80只新西蘭大白兔隨機分為兩組,建立股骨干非負重骨折動物模型,應用生物降解自鎖式捆綁帶固定骨折為實驗組,鋼絲固定骨折為對照組,分別于術后1、4、8、12周行生物力學檢查進行比較。結果:捆綁帶組在術后4、8、12周均比鋼絲組的彎曲強度高,但4周、12周時P gt;005,無統計學差異,8周時P lt;005,提示有統計學差異。離體同種固定物不同時間段抗拉強度自身比較:鋼絲固定術后4階段抗拉強度比較P gt;005,任何兩兩比較都沒有統計學差異,抗拉強度未隨術后時間延長發生明顯下降。捆綁帶固定術后4周與術后1周比較P gt;005,抗拉強度無明顯降低,但術后8周和術后12周時P lt;005,抗拉強度明顯下降。結論:生物降解自鎖式捆綁帶在非負重骨折治療中可發揮良好的固定作用。生物降解自鎖式捆綁帶降解時,應力傳導促進了骨折的愈合。
Abstract: Objective: To study the biomechanics function of selflocking cerclage band made of biodegradable material polyDLlactic acid (PDLLA) in the fixation of fractures. Methods: Eighty rabbits were divided into two groups. Femur fracture models were made. Fractures were fixed using biodegradable selflocking cerclage band in experimental group and metal fixation material in control group. The biomechanics was analyzed and compared after 1, 4, 8 and 12 weeks respectively． Results
: The bending strength of experimental group is more ber than that of control group after 4, 8 and 12 weeks, but it was not statistically significant at 4 and 12 weeks (P gt;005). It was statistically significant at 8 weeks (P lt;005). The tensile strength of the same cerclage instrument was compared at different stage in vitro, and the result of the control group was not statistically significant at the four stage (〖WTBX〗P〖WTBZ〗 gt;005). Regarding the changes of tensile strength of the cerclage instrument at different stage, the result of the experimental group was not statistically significant after 1 and 4 weeks (P gt;005). However, the decrease of tensile strength was statistically significant after 8 and 12 weeks (P lt;005). Conculsion: Biodegradable selflocking cerclage band could be used in thetreatment of nonweightbearing fractures. The stress force conducting promotes healing of fracture when the selflocking biodegradable cerclage band degrades.

Citation： LI Kainan,MA Yunhong,CHEN Taiyong,et al.. Biomechanical Study of Selflocking Cerclage Band Made of Degradable Material in the Fixation of Fractures. West China Medical Journal, 2009, 24(11): 3012-3015. doi: Copy

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