摘要:目的: 觀察急性鏈球菌感染后腎炎(APSGN)患兒血壓變化規律。 方法 :觀察15例重型APSGN(重型組)和20例普通型APSGN(普通組)患兒病程中各時期血壓及尿量變化,并進行免疫和生化指標對比。 結果 :APSGN患兒高血壓總共26例(7429%),其中重癥組高血壓14例(933%),普通組高血壓12例(60%),高血壓發生率重癥組高于普通組〖WTBX〗P  lt;005。重癥APSGN患兒入院時舒張壓、少尿期收縮壓舒張壓、多尿期舒張壓與普通組比較均有顯著性差異,〖WTBX〗P  lt;005;而且重癥APSGN與普通組在少尿期持續時間、尿量、多尿期持續時間、尿量的指標比較也均有顯著性差異,〖WTBX〗P  lt;005。重癥APSGN患兒血IgG、BUN、Cr明顯高于普通APSGN,P lt;005。 結論 :高血壓是APSGN主要臨床表現之一,血壓增高多發生于少尿期,但重癥APSGN患兒于多尿期出現血壓增高的第二次高峰,臨床上應注意監測,及時治療。
Abstract: Objective: To observe the law of the changes of children’s blood pressure after the infection of steptococcus with acute nephritis(APSGN).〖WTHZ〗Methods :Watching 15 cases of serious APSGN and 20 cases of ordinary APSGN for their changes in blood pressure and their urine amounts in various periods; contrasting their indexes in immunity and biochemistry.〖WTHZ〗Results :Among 26cases(7429%)of patients’high blood pressure with APSGN,of which 14cases (933%)are serious ones and 12cases (60%)are ordinary ones,the occurrence rate of the serious group is higher than that of the ordinary group, P lt;005At the initial stage, either the diastolic presssure or the diastolic pressure and the systolic pressure of the serious group with a small amount of unine, the diastolic pressure with a large amount of urine are evidently different from those of the ordinary group, P lt;005Furthermore,there are evident differences in the durations and amounts of urine with either a small or a large amount of urine, P lt;005The IgG,BUN and Cr of the serious group are evidently higher than those of the ordinary group,P lt;005 Conclusion :High blood pressure is one of the main clinical manifestations of APSGN.The increase of blood pressure mostly occurs during the period of a small amount of urine, but a second summit of high blood pressure with APSGN mostly appears in the period of a large amount of urine.It must be closely observed and therefore given the timely treatment.

Citation： HUANG Shiqiong,DAI Yinzhen,WANG Xiaogang.. Severe Acute Nephritis after Streptococcal Infection in children with Blood Pressure Changes and Related Factors. West China Medical Journal, 2009, 24(10): 2590-. doi: Copy

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