Comparison between Sufentanil and Fentanylon Their Clinical Effect in Neurosury_West China Medical Journal

Authors：

HUANG Kun , LIANG Peng , YANG Bangxiang.

Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu Sichuan 610041, China;

Corresponding?author：

Keywords：

舒芬太尼; 芬太尼; 血流動力學; 蘇醒; 術后痛

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目的:比較舒芬太尼與芬太尼復合七氟烷麻醉在神經外科手術中對血流動力學、拔管時間、蘇醒時間及術后疼痛情況的影響。方法:擇期開顱手術患者60例,隨機分為舒芬太尼(S)組和芬太尼(F)組,每組30例。將S和F的效能比定為10:l,復合咪唑安定、維庫溴胺、異丙酚來進行麻醉誘導;麻醉維持均復合七氟烷。分別記錄麻醉前、誘導后、插管時和拔管時血壓和心率變化;呼吸恢復、睜眼和拔管時間以及拔管后半小時疼痛評分(VAS評分)。結果:兩組麻醉誘導后收縮壓(SBP)、舒張壓(DBP)、心率(HR)均較誘導前有顯著性下降(P lt;0．05)。F組插管及拔管時,血流動力學變化均較S組有顯著性升高(P lt;0.05)。S組蘇醒期呼吸恢復、睜眼、拔管時間較F組明顯縮短;拔管后半小時疼痛評分(VAS評分)S組低于F組。結論:與芬太尼相比,等效劑量的舒芬太尼用于腦外科手術患者麻醉誘導可更有效地減輕全麻誘導氣管插管時的心血管反應;在麻醉蘇醒期,更有利于呼吸管理及術后鎮痛。舒芬太尼在神經外科麻醉中具有很好的臨床應用價值。

Citation： HUANG Kun,LIANG Peng,YANG Bangxiang.. Comparison between Sufentanil and Fentanylon Their Clinical Effect in Neurosury. West China Medical Journal, 2009, 24(8): 1986-1988. doi: Copy

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West China Medical Journal

Comparison between Sufentanil and Fentanylon Their Clinical Effect in Neurosury

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