Clincal Study of Noninvasive Ventilation for Respiratory Failure Resulting from Acute Exacerbations of Chronic Obstructive Pulmonary Disease_West China Medical Journal

Authors：

WAN Xiaobing , CHENG Yujie , LU Haiying , et al.

Department of Respiratory Disease, Sichuan Provence No.4 People’s Hospital, Chengdu 610016,China;

Corresponding?author：

Keywords：

雙水平氣道正壓通氣; 慢性阻塞性肺疾病; Ⅱ型呼吸衰竭

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目的:探討鼻(面)罩無創雙水平氣道正壓通氣(BiPAP)在慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭的治療作用。方法:入選病例60例,分為常規治療組28例,采用常規治療;呼吸機治療組32例,在常規資料基礎上加用BiPAP無創呼吸機治療,兩組患者心率,呼吸頻率,血氣分析比較。結果:呼吸機治療組患者心率,呼吸頻率,血氣分析的改善優于常規治療組,差異有統計學意義(P lt; 0.05)。結論:無創雙水平氣道正壓機械通氣輔助治療COPD合并Ⅱ型呼吸衰竭具有肯定的療效,能更快地緩解患者的臨床癥狀;提高PaO2,SaO2和降低PaCO2;能更好地促進病情的恢復,減少住院時間。

Citation： WAN Xiaobing,CHENG Yujie,LU Haiying,et al.. Clincal Study of Noninvasive Ventilation for Respiratory Failure Resulting from Acute Exacerbations of Chronic Obstructive Pulmonary Disease. West China Medical Journal, 2009, 24(6): 1431-1433. doi: Copy

1.	朱蕾,鈕善福,張書平,等.經面罩機械通氣治療慢性阻塞性肺疾病呼吸衰竭患者的回顧性分析[J].中華結核和呼吸雜志,2003,26(7):407-410.
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5.	曹志新,王辰.無創機械通氣的應用范圍及指征[J]. 中華結核和呼吸雜志,2002,25(3):136-137.
6.	Pauwels RA, Buist AS, Calverlry PMA, et al.NHLBI/WHO global initiative for chronic obstructive lung disease (GOLD)workshop summary.Global strategy for the diagnosis,management,and prevention of chronic obstructive lung disease[J]. Am J Respir Crit Care Med, 2001,163(5):1257-1276.
7.	王宋平,李國平,王榮麗,等.無創通氣治療慢性阻塞性肺疾病急性呼吸衰竭的臨床研究[J].中國呼吸與危重監護雜志,2002,1(4):233-235.

1. 朱蕾,鈕善福,張書平,等.經面罩機械通氣治療慢性阻塞性肺疾病呼吸衰竭患者的回顧性分析[J].中華結核和呼吸雜志,2003,26(7):407-410.
2. 中華醫學會呼吸病分會.慢性阻塞性肺疾病診治指南[J]. 中華結核和呼吸雜志,2002,25(8):453-460.
3. CONTIG, ANTONELLIM, NAVALESIP, et al. Noninvasive vs. conventional mechanical ventilation in patients with chronic obstructive pulmonary disease after failure of medical treatment in the ward a randomized trial[J].Intensive Care Med,2002,28(12):1701-1707.
4. 王辰,張洪玉.改進慢性阻塞性肺疾病合并呼吸衰竭的機械通氣策略[J].中華內科雜志,2000,39(6):369.
5. 曹志新,王辰.無創機械通氣的應用范圍及指征[J]. 中華結核和呼吸雜志,2002,25(3):136-137.
6. Pauwels RA, Buist AS, Calverlry PMA, et al.NHLBI/WHO global initiative for chronic obstructive lung disease (GOLD)workshop summary.Global strategy for the diagnosis,management,and prevention of chronic obstructive lung disease[J]. Am J Respir Crit Care Med, 2001,163(5):1257-1276.
7. 王宋平,李國平,王榮麗,等.無創通氣治療慢性阻塞性肺疾病急性呼吸衰竭的臨床研究[J].中國呼吸與危重監護雜志,2002,1(4):233-235.

West China Medical Journal

Clincal Study of Noninvasive Ventilation for Respiratory Failure Resulting from Acute Exacerbations of Chronic Obstructive Pulmonary Disease

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