Color Sonography Diagnosis and Clinical Analysis of Gastrointestinal Stromal Tumor_West China Medical Journal

Authors：

ZHANG Mingzhi ,  ZHUANG Hua , PENG Yulan

Department of Ultrasonography, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R.China;

Corresponding?author：

ZHUANG Hua, Email: zmz88096157@sina.com

Keywords：

胃腸道間質瘤; 彩色多普勒超聲

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【摘要】　目的　探討胃腸道間質瘤(GIST)彩色多普勒超聲表現及其在診斷中的應用價值。　方法　回顧性分析2008年1月-2010年7月75例經病理證實的GIST的彩色多普勒超聲聲像圖表現，將其與手術病理結果進行對比分析。　結果　 GIST患者中男性高危險度腫瘤的比例較女性高（χ2=7.210，P lt;0.01）。腫瘤的大小、內部回聲與其病理危險度高低有關:危險度低者、腫瘤最大徑 lt;5 cm，內部回聲較均勻；危險度高者，腫瘤最大徑≥5 cm，內部回聲不均勻。腫瘤的彩色血流分布與其危險度高低無明顯相關。常規的超聲檢查對腫瘤檢出率較高，在胃及直腸的GIST診斷準確率高于其他部位的GIST。　結論　彩色多普勒超聲檢查有助于GIST的定位及分化程度的判斷，可作為首選檢查方法。
【Abstract】　Objective　 To investigate the value of ultrasonography in the diagnosis of gastrointestinal stromal tumors (GIST).　Methods　 The color sonographic performances obtained in 75 patients with pathologically proved GIST from January 2008 to July 2010 were retrospectively analyzed. The sonographic findings were compared with pathological results.　Results　 The proportion of high-risk cancer in male patients with GIST was higher than that in women (χ2=7.210, P lt;0.01). The tumor size and internal echo level were related to its pathologic risk: in low-risk GIST, maximum tumor diameter was lt;5 cm, and internal echo was more homogeneous; in high-risk GIST, maximum tumor diameter was ≥ 5 cm and internal echo was heterogeneous. There was no statistical difference between tumor blood flow distribution and GIST risk. Routine sonography examination had a higher rate of cancer detection and had a higher accuracy in the diagnosis of GIST in the stomach and rectum than those in the other parts.　Conclusion　 Sonography helps to locate and diagnose malignant GIST, which is a common and preferred screening method.

Citation： ZHANG Mingzhi,ZHUANG Hua,PENG Yulan. Color Sonography Diagnosis and Clinical Analysis of Gastrointestinal Stromal Tumor. West China Medical Journal, 2010, 25(11): 1956-1959. doi: Copy

1.	中國胃腸道間質瘤專家組. 中國胃腸道間質瘤診斷治療共識[J]. 中華病理學雜志, 2009, 38 (10): 697-702.
2.	王悅, 李立. 經直腸彩色多普勒超聲鑒別卵巢腫瘤良惡性的診斷價值[J]. 中國醫學影像技術, 1999, 15: 720-721.
3.	Kurjak A, Kuppesic S, Anic T. Three-dimensional ultrasound and power Doppler improve the diagnosis of ovarian lesions[J]. Gynecol Oncol, 2000, 76: 28-32.
4.	Singer S, Rubin Bp, Lux Ml, et al. Prognostic value of KIT mutation type, mitotic activity, and histologic subtype in gastrointestinal stromal tumors [J]. J Clin Oncol, 2002, 20 (18): 3898-3905.
5.	Liegl-Tzwanger B, Fletcher JA, Fletcher CD. Gastrointestinal stromal tumors[J]. Virchows Arch, 2010, 456 (2): 111-127.
6.	Krokowskim, Jocham D, Choi H, et al. Malignant extragastrointestinal stromal tumor of bladder[J]. J Urol, 2003, 169(5): 1790.
7.	Weppler EH, Gaertner EM. Malignant extragastrointestinal stromal tumor presenting as a vaginalmass: report of an unusual case with literature review[J]. Int J Gynecol Cancer, 2005, 15(6): 1169.
8.	張新民, 梁青春, 唐蜜, 等. 胃腸道間質瘤的臨床病理形態和免疫組織化學特點[J]. 中國現代醫學雜志, 2004, 14(9): 93-95.
9.	Clary BM, Dematteo RP, Lewis JJ, et al. Gastrointestinal stromal tumors and leiomyosarcoma of the abdomen and retroperitoneum: a clinical comparison[J]. Ann Surg Oncol, 2001, 8(4): 290-299.
10.	鄒慶, 官泳松. 胃腸間質瘤研究新進展[J]. 胃腸病學和肝病學雜志, 2009, 18(1): 73-77.
11.	李洪林, 郝玉芝, 陳宇, 等. 胃腸道間質瘤的超聲診斷[J]. 中國超聲醫學雜志, 2005, 21(12): 921-923.

1. 　中國胃腸道間質瘤專家組. 中國胃腸道間質瘤診斷治療共識[J]. 中華病理學雜志, 2009, 38 (10): 697-702.
2. 　王悅, 李立. 經直腸彩色多普勒超聲鑒別卵巢腫瘤良惡性的診斷價值[J]. 中國醫學影像技術, 1999, 15: 720-721.
3. 　Kurjak A, Kuppesic S, Anic T. Three-dimensional ultrasound and power Doppler improve the diagnosis of ovarian lesions[J]. Gynecol Oncol, 2000, 76: 28-32.
4. 　Singer S, Rubin Bp, Lux Ml, et al. Prognostic value of KIT mutation type, mitotic activity, and histologic subtype in gastrointestinal stromal tumors [J]. J Clin Oncol, 2002, 20 (18): 3898-3905.
5. 　Liegl-Tzwanger B, Fletcher JA, Fletcher CD. Gastrointestinal stromal tumors[J]. Virchows Arch, 2010, 456 (2): 111-127.
6. 　Krokowskim, Jocham D, Choi H, et al. Malignant extragastrointestinal stromal tumor of bladder[J]. J Urol, 2003, 169(5): 1790.
7. 　Weppler EH, Gaertner EM. Malignant extragastrointestinal stromal tumor presenting as a vaginalmass: report of an unusual case with literature review[J]. Int J Gynecol Cancer, 2005, 15(6): 1169.
8. 　張新民, 梁青春, 唐蜜, 等. 胃腸道間質瘤的臨床病理形態和免疫組織化學特點[J]. 中國現代醫學雜志, 2004, 14(9): 93-95.
9. 　Clary BM, Dematteo RP, Lewis JJ, et al. Gastrointestinal stromal tumors and leiomyosarcoma of the abdomen and retroperitoneum: a clinical comparison[J]. Ann Surg Oncol, 2001, 8(4): 290-299.
10. 　鄒慶, 官泳松. 胃腸間質瘤研究新進展[J]. 胃腸病學和肝病學雜志, 2009, 18(1): 73-77.
11. 　李洪林, 郝玉芝, 陳宇, 等. 胃腸道間質瘤的超聲診斷[J]. 中國超聲醫學雜志, 2005, 21(12): 921-923.

West China Medical Journal

Color Sonography Diagnosis and Clinical Analysis of Gastrointestinal Stromal Tumor

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