【摘要】 目的 探討小兒外科圍手術期抗菌藥物應用情況，為兒外科臨床合理、規范使用抗菌藥物提供參考。 方法 隨機抽取兒外科2008年1月-2009年10月出院手術病歷763份，對抗菌藥物的應用情況進行分析。 結果 763份病歷顯示，患兒均使用了抗菌藥物，應用率高達100%。抗菌藥物品種應用最多的是青霉素類518例（48.05%），其次為頭孢菌素類336例（31.17%），其他抗菌藥物（林可霉素類、硝基咪唑類、大環內酯類等）224例（20.78%）。一聯用藥574例（75.00%），二聯用藥147例（19.00%），三聯及以上用藥42例（6.00%）。其中， 99例（12.98%）做過病原學檢測，39例有藥敏試驗依據（5.11%），以G+中的葡萄球菌為主。 結論 小兒外科圍手術期抗菌藥物目前應用存在一定的不合理，臨床應當嚴格按照《抗菌藥物臨床應用指導原則》合理、規范使用抗菌藥物。
【Abstract】 Objective To investigate the perioperative use of antibiotics in children’s surgery of our hospital to guide it’s reasonable and normal use. Methods A total of 763 patients who discharged from our hospital between January 2008 and October 2009 were sampled randomly for statistical analysis regarding the utilization. Results Of the 763 cases reviewed, all cases (100%) received antibiotics. In terms of the application of antibiotics, penicillins were predominantly used in 518 patients (48.05%), followed by cephalosporins in 336 patients (31.17%) and other antibiotics such as lincomycins nitroimidazoles and macrolides in 224 patients (20.78%). 574 patients (75.00%) received one antibiotic, 147 (19.00%) received two antibiotics and 42(6.00%) received at least three antibiotics concomitantly. Only 99 patients (12.98%) received etiological test and 39 patients (5.11%) received susceptibility test during antibiotic ues, most of them are G+ staphylococcus infected. Conclusion The perioperative use of antibiotics in our hospital is somewhat unreasonable, thus monitoring closely on which should be performed to promote their reasonable and normal use.
Citation： ZHANG Dan. Perioperative Use of Antibiotics in Children’s Surgery. West China Medical Journal, 2010, 25(8): 1517-1519. doi: Copy
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