Therapeutic Effect of Hyperbaric Oxygen Combined with Medical Treatment on Sudden Deafness_West China Medical Journal

Authors：

HUANG Hongxing ,  YANG Li , HUANG Yuan , TANG Zixuan , ZHAO Zhidong

Department of Otolaryngology-Head and Neck Surgery, Central Hospital of Suining City, Suining, Sichuan 629000, P. R. China;

Corresponding?author：

YANG Li, Email: hhx1964032@163.com

Keywords：

突發性耳聾; 高壓氧; 療效

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【摘要】　目的　探討高壓氧聯合藥物治療突發性耳聾（sudden deafness， SD）的療效。　方法　 2008年2月-2010年7月，對174例SD患者采用高壓氧（治療壓力0.2 MPa）及配合擴血管、營養神經等藥物進行治療，并觀察其療效。　結果　高壓氧聯合藥物治療SD總有效率為85.7％，SD的發病就診時間是影響預后的主要因素，發病就診時間≤7 d時，治療有效率可達95.6%；≥15 d時，療效明顯降低。　結論　高壓氧聯合藥物治療SD療效確切，且高壓氧治療越早療效越好。
【Abstract】　Objective　 To observe the therapeutic effect of hyperbaric oxygen combined with medical treatment on sudden deafness. 　Methods　 Between February 2008 and July 2010, 174 patients with sudden deafness were treated by a combined therapy, including hyperbaric oxygen and medicals. The therapeutic effect was analyzed.　Results　 The total effective rate was 85.7％. The simultaneous phenomenon such as vertigo and vomiting and onset-diagnosis duration were the two major factors affecting the prognosis. When the onset-diagnosis duration was ≤7 days, the effective rate reached 95.6%; when the onset-diagnosis duration was≥15 days, the therapeutic effect decreased significantly.　Conclusion　 Hyperbaric oxygen combined with medical treatment is effective for sudden deafness, and the hyperbaric oxygen treatment should be performed as earlier as possible.

Citation： HUANG Hongxing,YANG Li,HUANG Yuan,TANG Zixuan,ZHAO Zhidong. Therapeutic Effect of Hyperbaric Oxygen Combined with Medical Treatment on Sudden Deafness. West China Medical Journal, 2011, 26(9): 1376-1378. doi: Copy

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12.	劉陽云, 孫大江, 邵姍, 等. 高壓氧對不同聽力損失程度與聽力曲線突發性聾患者的療效觀察[J]. 臨床耳鼻喉頭頸外科雜志, 2010, 24(19): 890-894.

1. 　張曉彤, 許珉, 段茂利, 等. 突發性聾臨床流行病學分析[J]. 中華耳科學雜志, 2009, 7(2): 152-156.
2. 　Ban JH. Jin SM. A clinical analysis of psychogenic sudden deafnoss[J]. Otolaryngol Head Neck Surg., 2006, 134(6): 970-974.
3. 　中華耳鼻咽喉頭頸外科雜志編輯委員會, 中華醫學會耳鼻咽喉頭頸外科學分會. 突發性聾的診斷和治療指南[J]. 中華耳鼻咽喉頭頸外科雜志, 2006, 41(8): 569.
4. 　田巍, 許羅俊, 王海英, 等. 高壓氧治療突發性耳聾的療效觀察[J]. 中國康復醫學雜志, 2008, 23(11): 1409-1410.
5. 　Bennett MH, Kertesz T, Yeung P. Hyperbaric oxygen for idiopathic sudden sensorineural hearing loss and tinnitus[J]. Coehrane Database Syst Rev, 2007, 24(1): 97.
6. 　黃懷, 李寧, 古菁. 高壓氧治療突發性耳聾的研究進展[J]. 重慶醫學, 2010, 39(8): 943-944.
7. 　Suzuki H, Fuj imura T, Shiomori T, et al. Prostaglandin E1 versus steroid in combination with hyperbaric oxygen therapy for idiopathic sudden sensorineural hearing loss[J]. Auris Nasus Larynx, 2008, 35(2): 192.
8. 　王海妹, 王繼紅, 周小柳. 不同年齡段突發性耳聾臨床分析[J]. 第四軍醫大學學報, 2008, 29(18): 1721.
9. 　馬芙蓉, 謝立峰, 趙一鳴. 突發性耳聾預后因素回歸樹分析[J]. 中國耳鼻咽喉頭頸外科, 2005, 12(9): 577-579.
10. 　侯志強, 蘭蘭, 王大勇, 等. 老年突發性耳聾的臨床特征和轉歸[J]. 中華耳科學雜志, 2010, 8(2): 141-147.
11. 　Giuseppe B, Giuseppe T, Paola C, et al. Effectiveness of hyperbaric oxygen therapy for hearing loss after cardiac surgery[J]. Ann Thorac Surg, 2007, 83 (1): 9-10.
12. 　劉陽云, 孫大江, 邵姍, 等. 高壓氧對不同聽力損失程度與聽力曲線突發性聾患者的療效觀察[J]. 臨床耳鼻喉頭頸外科雜志, 2010, 24(19): 890-894.

West China Medical Journal

Therapeutic Effect of Hyperbaric Oxygen Combined with Medical Treatment on Sudden Deafness

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