Effect of Insulin Pump on Type 2 Diabetes Mellitus Combined with Gastric Cancer during the Perioperative Period_West China Medical Journal

Authors：

QIAO Wu ¹ ,  WANG Xiaohua ² , GAO Liyan ¹ , MENG Yanrong ³ , WANG Yanxiang ¹

1. Department of Endocrinology; 2. Department of General Surgery, Luanxian People′s Hospital of Tangshan Citiy, Tangshan, Hebei 063700, P. R. China; 3. Department of Internal Medicine, County Hospital of Luannan, Tangshan, Hebei 063700, P. R. China;

Corresponding?author：

WANG Xiaohua, Email: wangxiaohua.1996@163.com

Keywords：

胰島素泵; 圍術期; 糖尿病; 胃癌

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【摘要】　目的　觀察糖尿病合并胃癌圍手術期患者應用胰島素泵的治療效果。　方法　 2004年1月-2010年12月收治的胃癌合并2型糖尿病患者86例，將患者隨機分為常規組（A組）46例和胰島素泵組（B組）40例，比較兩組患者在血糖控制、手術并發癥方面的差異。　結果　 B組與A組出院時，空腹血糖以及餐后血糖均能達標，但B組明顯好于A組（P lt;0.05）；B組胃排空障礙發生率降低（P lt;0.05）。　結論　胰島素泵能更好地控制血糖、減少手術并發癥的發生。
【Abstract】　Objective　 To observe the therapeutic effect of insulin pump on type 2 diabetes mellitus combined with gastric cancer during the perioperative period. 　Methods　 Between January 2004 and December 2010, 86 patients with type 2 diabetes mellitus combined with gastric cancer were randomly divided into control group (group A, 46 cases) and insulin pump group (group B, 40 cases). The differences in blood glucose level and infection rate of operation incisions were compared between the two groups.　Results　 Both groups reached the aimed glucose level (fasting blood glucose and postprandial blood glucose) at the discharge from the hospital, which in group B were significantly better than those in group A （P lt;0.05）. The obstruction of gastric emptying in group B decreased significantly (P lt;0.05).　Conclusion　 Insulin pump can control the blood glucose and reduce the surgical complications．

Citation： QIAO Wu,WANG Xiaohua,GAO Liyan,MENG Yanrong,WANG Yanxiang. Effect of Insulin Pump on Type 2 Diabetes Mellitus Combined with Gastric Cancer during the Perioperative Period. West China Medical Journal, 2011, 26(9): 1303-1305. doi: Copy

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9.	王群, 曹偉, 趙怡. 強化血糖控制與糖尿病患者胃腸腫瘤手術并發癥的關系[J]. 實用癌癥雜志, 2010, 25(4): 381-383.
10.	徐偉. 手術后功能性胃排空障礙的診斷與處理[J]. 浙江臨床醫學, 2008, 10(6): 777.
11.	Samsom M, Bharucha A, Gerich JE, et al. Diabetes mellitus and gastric emptying:questions and issues in clinical practice[J]. Diabetes Metab Res Rev, 2009, 25(6): 502-514.
12.	張鳴杰, 張國雷, 袁文斌. 胃大部切除術后胃癱綜合征的臨床危險因素分析[J]. 臨床外科雜志, 2007, 15(10): 683-684.

1. 　盧瑜, 方勇, 王青青, 等. 糖尿病與惡性腫瘤關系的回顧性臨床研究[J]. 中華內分泌代謝雜志, 2010, 26(3): 183-187.
2. 　Jee SH, Ohrr H, Sull JW, et al. Fasting serum glucose level and cancer risk in Korean men and women[J]. JAMA, 2005, 293(2): 194-202.
3. 　Stattin P, Bjr O, Ferrari P, et al. Prospective study of hyperglycemia and cancer risk[J]. Diabetes Care, 2007, 30(3): 561-567.
4. 　Yamagata H, Kiyohara Y, Nakamura S, et al. Impact of fasting plasma glucose levels on gastric cancer incidence in a general Japanese population: the hisayama study[J]. Diabetes Care, 2005, 28(4): 789-794.
5. 　Bowker SL, Majumdar SR, Veuqelers P, et al. Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin[J]. Diabetes Care, 2006, 29(2): 254-258.
6. 　Nassar AA, Boyle ME, Seifert KM, et al. Insulin pump therapy in patients with diabetes undergoing surgery[J]. Endocr Pract, 2011, 29: 1-22.
7. 　張麗偉. 胰島素泵治療糖尿病患者的療效觀察[J]. 中國醫藥導報, 2007, 4(20): 125.
8. 　黃紹軍, 曹長峰. 胰島素泵在圍手術期糖尿病中的臨床應用[J]. 中國現代醫生, 2008, 46(21): 111-112.
9. 　王群, 曹偉, 趙怡. 強化血糖控制與糖尿病患者胃腸腫瘤手術并發癥的關系[J]. 實用癌癥雜志, 2010, 25(4): 381-383.
10. 　徐偉. 手術后功能性胃排空障礙的診斷與處理[J]. 浙江臨床醫學, 2008, 10(6): 777.
11. 　Samsom M, Bharucha A, Gerich JE, et al. Diabetes mellitus and gastric emptying:questions and issues in clinical practice[J]. Diabetes Metab Res Rev, 2009, 25(6): 502-514.
12. 　張鳴杰, 張國雷, 袁文斌. 胃大部切除術后胃癱綜合征的臨床危險因素分析[J]. 臨床外科雜志, 2007, 15(10): 683-684.

West China Medical Journal

Effect of Insulin Pump on Type 2 Diabetes Mellitus Combined with Gastric Cancer during the Perioperative Period

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