The Clinical Efficacy of Specially-made “Yinchen Chaiping Tang” Decoction in Treating Chronic Hepatitis B_West China Medical Journal

Authors：

GAO Feng , LUuml

Chengdu Infectious Disease Hospital, Chengdu, Sichuan 610061, P. R. China;

Corresponding?author：

Keywords：

茵陳柴平湯; 慢性乙型肝炎，重度; 療效觀察

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目的　觀察茵陳柴平湯治療重度慢性乙型肝炎的療效及不良反應。方法　2009年3月－2010年3月，選擇采用茵陳柴平湯聯合常規保肝藥物治療50例重度慢性乙型肝炎患者（治療組），并與50例僅用常規保肝藥物治療的重度慢性乙型肝炎患者（對照組）進行比較，觀察治療2、4周時的臨床癥狀、肝功能及凝血酶原活動度等指標的變化。結果　治療2、4周時，治療組在肝功能及凝血酶原活動度等指標均有顯著改善，無嚴重不良反應；4周時，治療組的癥狀緩解率（84%）明顯高于對照組（66%）；其總有效率（96%）亦高于對照組（80%）。結論　茵陳柴平湯治療重度慢性乙型肝炎具有較好的臨床療效，且無嚴重不良反應。

Citation： GAO Feng,LUuml,Yi. The Clinical Efficacy of Specially-made “Yinchen Chaiping Tang” Decoction in Treating Chronic Hepatitis B. West China Medical Journal, 2012, 27(6): 870-872. doi: Copy

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2. 　中華醫學會傳染病與寄生蟲病學分會、肝病學分會. 病毒性肝炎防治方案[J]. 中華肝臟病雜志, 2000, 8(6): 342-329.
3. 　Ganem D, Prince AM. Hepatitis B virus infection-natural history and clinical consequences[J]. N Engl J Med, 2004, 350(11): 1118-1129.
4. 　World Health Organization. Hepatitis B (Revised August 2008)(2010-12-09)[2011-09-24].[EB/OL]. http://www.who.int/medicacentre/fact-sheets/fs204/en/.
5. 　European Association For The Study Of The Liver. EASL Clinical Practice Guidelines: management of chronic hepatitis B[J]. J Hepatol, 2009, 50 (2): 227-242.
6. 　Liu Y, Wang CM, Cheng J, et al. Hepatitis B virus in tenofovir-naive Chinese patients with chronic hepatitis B contains no mutation of rtA194T conferring a reduced tenofovir susceptibility[J]. Chin Med J (Engl) 2009,122 (13): 1585-1586.
7. 　Lavanchy D. Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures[J]. J Viral Hepatitis, 2004, 11 (2): 97-107.
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10. 　王伯祥. 慢性乙型肝炎中醫藥證治研究進展[J]. 世界中醫藥, 2007, 1(2): 61-62.
11. 　《中醫藥創新與發展》編委會. 中醫藥防治在重大傳染病的研究[M]. 成都:四川科學技術出版社, 2010: 105-240.

West China Medical Journal

The Clinical Efficacy of Specially-made “Yinchen Chaiping Tang” Decoction in Treating Chronic Hepatitis B

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