內囊警示綜合征研究進展_West China Medical Journal

Authors：

胡小輝 ¹ , 鄭珍珍 ² ,  姚長江 ¹

Corresponding?author：

姚長江, Email: smilewheeler@163.com

Keywords：

內囊警示綜合征; 短暫缺血性發作; 橋腦警示綜合征

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

內囊警示綜合征是一種反復刻板發作的腦短暫缺血性疾病，有時可類似癲癇發作。其綜合征的病因可以是腦大血管病、腦小血管病、橋腦梗死、硬膜靜脈竇血栓形成、間歇性血壓下降等。綜合征發展為永久性腦梗死的風險較高，并且常用于短暫缺血性發作的多種治療方法（血液稀釋、抗血小板聚集、溶栓治療等），單獨運用基本不能阻止發生永久性腦梗死的結局。聯合療法（抗血小板聚集、擴充血漿容量、溶栓治療等聯合）、顱內血管重塑術、抗癲癇、糖皮質激素、免疫抑制和藥物性增加血壓治療可能對一些內囊警示綜合征的患者有效。

Citation： 胡小輝,鄭珍珍,姚長江. 內囊警示綜合征研究進展. West China Medical Journal, 2012, 27(3): 459-462. doi: Copy

1.	Donnan GA, O’Malley HM, Quang L, et al. The capsular warning syndrome: pathogenesis and clinical features[J]. Neurol, 1993, 43(5): 957-962.
2.	陳智才, 胡笑月, 周佳君, 等. 內囊警示綜合征11例臨床分析[J]. 中華神經科雜志, 2010, 43(12): 824-827.
3.	Muengtaweepongsa S, Singh NN, Cruz-Flores S. Pontine warning syndrome: case series and review of literature[J]. J Stroke Cerebrovasc Dis, 2010, 19(5): 353-356.
4.	Staaf G, Geijer B, Lindgren A, et al. Diffusion-weighted MRI findings in patients with capsular warning syndrome[J]. Cerebrovasc Dis, 2004, 17(1): 1-8.
5.	Farrar J, Donnan GA. Capsular warning syndrome preceding pontine infarction[J]. Stroke, 1993, 24(5): 762.
6.	Ferro JM, Falcao F, Melo TP, et al. Dural sinus thrombosis mimicking “capsular warning syndrome”[J]. J Neurol, 2000, 247(10): 802-803.
7.	Lee J, Albers GW, Marks MP, et al. Capsular warning syndrome caused by middle cerebral artery stenosis[J]. J Neurol Sci, 2010, 296(1-2): 115-120.
8.	Prabhakaran S, Krakauer JW. Multiple reversible episodes of subcortical ischemia following postcoital middle cerebral artery dissection[J]. Arch Neurol, 2006, 63(6): 891-893.
9.	Caporale CM, Notturno F, Caulo M, et al. Capsular warning syndrome mimicking a jacksonian sensory march[J]. J Neurol Sci, 2009, 285(1-2): 262-264.
10.	Pantoni L. Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges[J]. Lancet Neurol, 2010, 9(7): 689-701.
11.	Tang CW, Wang PN, Lin KP, et al. Microscopic polyangiitis presenting with capsular warning syndrome and subsequent stroke[J]. J Neurol Sci, 2009, 277(1-2): 174-175.
12.	Ferro JM, Canhao P, Stam J, et al. Prognosis of cerebral vein and dural sinus thrombosis: results of the international study on cerebral vein and dural sinus thrombosis (ISCVT)[J]. Stroke, 2004, 35(3): 664-670.
13.	Manzano-palomo S, Egido-Herrero JA, Saiz-Ayala A, et al. Transient ischemic attack: the only presenting syndrome of dural sinus thrombosis[J]. Neurologi, 2006, 21(3): 155-158.
14.	Wasay M, Bakshi R, Bobustuc G, et al. Cerebral venous thrombosis: analysis of a multicenter cohort from the United States[J]. J Stroke Cerebrovasc Dis, 2008, 17(2): 49-54.
15.	Lalive PH, Mayor I, Sztajzel R. The role of blood pressure in lacunar strokes preceded by TIAs[J]. Cerebrovasc Dis, 2003, 16(1): 88-90.
16.	Caplan L. Intracranial branch atheromatous disease: a neglected, understudied, and underused concept[J]. Neurol, 1989, 39(9): 1246-1250.
17.	山本康正. Branch atheromatous disease (BAD) の概念とその臨床意義[J]. 臨床神経, 2010, 50(11): 914-917.
18.	楊任民, 徐銀. 分支動脈粥樣硬化病附3例報告及文獻復習[J]. 中國臨床神經科學, 2010, 18(4): 396-400.
19.	武田英孝, 高木誠, 山本康正, 他. BADをどぅ治療するか[J]. 臨床神経, 2010, 50(11): 921-924.
20.	田口芳治, 高嵨修太郎, 溫井孝昌, 他. Capsular warning syndrome を呈したbranch atheromatous disease の1例[J]. 臨床神経, 2010, 50(5): 320-324.
21.	Vivanco-Hidalgo RM, Rodriguez-Campello A, Ois A, et al. Thrombolysis in capsular warning syndrome[J]. Cerebrovasc Dis, 2008, 25(5): 508-510.
22.	Bruce NT, Neil WP, Zivin JA. Medico-legal aspects of using tissue plasminogen activator in acute ischemic stroke[J]. Cerebrovasc Dis and Stroke, 2011, 13(3): 233-239.
23.	Chernyshev OY, Martin-Schild S, Albright KC, et al. Safety of tPA in stroke mimics and neuroimaging-negative cerebral ischemia[J]. Neurol, 2010, 74(17): 1340-1345.
24.	Fahey CD, Alberts MJ, Bernstein RA. Oral clopidogrel load in aspirin-resistant capsular warning syndrome[J]. Neurocrit Care, 2005, 2(2): 183–184.
25.	斯曉燕, 趙永強. 阿司匹林抵抗研究進展[J]. 中國醫學科學院學報, 2009, 31(5): 644-650.
26.	Ozben S, Ozben B, Tanrikulu AM, et al. Aspirin resistance in patients with acute ischemic stroke[J]. J Neurol, 2011, 258(11): 1979-1986.

1. 　Donnan GA, O’Malley HM, Quang L, et al. The capsular warning syndrome: pathogenesis and clinical features[J]. Neurol, 1993, 43(5): 957-962.
2. 　陳智才, 胡笑月, 周佳君, 等. 內囊警示綜合征11例臨床分析[J]. 中華神經科雜志, 2010, 43(12): 824-827.
3. 　Muengtaweepongsa S, Singh NN, Cruz-Flores S. Pontine warning syndrome: case series and review of literature[J]. J Stroke Cerebrovasc Dis, 2010, 19(5): 353-356.
4. 　Staaf G, Geijer B, Lindgren A, et al. Diffusion-weighted MRI findings in patients with capsular warning syndrome[J]. Cerebrovasc Dis, 2004, 17(1): 1-8.
5. 　Farrar J, Donnan GA. Capsular warning syndrome preceding pontine infarction[J]. Stroke, 1993, 24(5): 762.
6. 　Ferro JM, Falcao F, Melo TP, et al. Dural sinus thrombosis mimicking “capsular warning syndrome”[J]. J Neurol, 2000, 247(10): 802-803.
7. 　Lee J, Albers GW, Marks MP, et al. Capsular warning syndrome caused by middle cerebral artery stenosis[J]. J Neurol Sci, 2010, 296(1-2): 115-120.
8. 　Prabhakaran S, Krakauer JW. Multiple reversible episodes of subcortical ischemia following postcoital middle cerebral artery dissection[J]. Arch Neurol, 2006, 63(6): 891-893.
9. 　Caporale CM, Notturno F, Caulo M, et al. Capsular warning syndrome mimicking a jacksonian sensory march[J]. J Neurol Sci, 2009, 285(1-2): 262-264.
10. 　Pantoni L. Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges[J]. Lancet Neurol, 2010, 9(7): 689-701.
11. 　Tang CW, Wang PN, Lin KP, et al. Microscopic polyangiitis presenting with capsular warning syndrome and subsequent stroke[J]. J Neurol Sci, 2009, 277(1-2): 174-175.
12. 　Ferro JM, Canhao P, Stam J, et al. Prognosis of cerebral vein and dural sinus thrombosis: results of the international study on cerebral vein and dural sinus thrombosis (ISCVT)[J]. Stroke, 2004, 35(3): 664-670.
13. 　Manzano-palomo S, Egido-Herrero JA, Saiz-Ayala A, et al. Transient ischemic attack: the only presenting syndrome of dural sinus thrombosis[J]. Neurologi, 2006, 21(3): 155-158.
14. 　Wasay M, Bakshi R, Bobustuc G, et al. Cerebral venous thrombosis: analysis of a multicenter cohort from the United States[J]. J Stroke Cerebrovasc Dis, 2008, 17(2): 49-54.
15. 　Lalive PH, Mayor I, Sztajzel R. The role of blood pressure in lacunar strokes preceded by TIAs[J]. Cerebrovasc Dis, 2003, 16(1): 88-90.
16. 　Caplan L. Intracranial branch atheromatous disease: a neglected, understudied, and underused concept[J]. Neurol, 1989, 39(9): 1246-1250.
17. 　山本康正. Branch atheromatous disease (BAD) の概念とその臨床意義[J]. 臨床神経, 2010, 50(11): 914-917.
18. 　楊任民, 徐銀. 分支動脈粥樣硬化病附3例報告及文獻復習[J]. 中國臨床神經科學, 2010, 18(4): 396-400.
19. 　武田英孝, 高木誠, 山本康正, 他. BADをどぅ治療するか[J]. 臨床神経, 2010, 50(11): 921-924.
20. 　田口芳治, 高嵨修太郎, 溫井孝昌, 他. Capsular warning syndrome を呈したbranch atheromatous disease の1例[J]. 臨床神経, 2010, 50(5): 320-324.
21. 　Vivanco-Hidalgo RM, Rodriguez-Campello A, Ois A, et al. Thrombolysis in capsular warning syndrome[J]. Cerebrovasc Dis, 2008, 25(5): 508-510.
22. 　Bruce NT, Neil WP, Zivin JA. Medico-legal aspects of using tissue plasminogen activator in acute ischemic stroke[J]. Cerebrovasc Dis and Stroke, 2011, 13(3): 233-239.
23. 　Chernyshev OY, Martin-Schild S, Albright KC, et al. Safety of tPA in stroke mimics and neuroimaging-negative cerebral ischemia[J]. Neurol, 2010, 74(17): 1340-1345.
24. 　Fahey CD, Alberts MJ, Bernstein RA. Oral clopidogrel load in aspirin-resistant capsular warning syndrome[J]. Neurocrit Care, 2005, 2(2): 183–184.
25. 　斯曉燕, 趙永強. 阿司匹林抵抗研究進展[J]. 中國醫學科學院學報, 2009, 31(5): 644-650.
26. 　Ozben S, Ozben B, Tanrikulu AM, et al. Aspirin resistance in patients with acute ischemic stroke[J]. J Neurol, 2011, 258(11): 1979-1986.

West China Medical Journal

內囊警示綜合征研究進展

Abstract Full text Figures/Tables Video References Cited by

Format

Content