Influence of Different Diagnostic Standards on the Prevalence of Irritable Bowel Syndrome among Middle School Students in Areas Affected by Wenchuan Earthquake_West China Medical Journal

Authors：

ZHENG Shicheng ¹ , FU Wanchao ¹ , HE Ying ¹ , DONG Xiaowei ¹ , WANG Yiping ² , ZHANG Qiang. ³

1. Department of Gastroenterology, the First People’s Hospital of Longquanyi District, Chengdu, Sichuan 610100, P. R. China; 2. Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China; 3. Department of Health Statistics, West China School of Public Health, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding?author：

Keywords：

汶川地震災區; 中學生; 腸易激綜合征; 標準

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

目的　調查汶川地震災區中學生腸易激綜合征（IBS）的患病情況，分析羅馬Ⅱ和羅馬Ⅲ診斷標準對該人群IBS患病率的影響。方法　在汶川地震后2年半和3年，分別用羅馬Ⅱ和羅馬Ⅲ標準制定IBS中學生問卷調查表對地震災區和非地震災區5所中學的中學生進行2次調查，分析比較IBS患病率的變化。結果　用羅馬Ⅱ標準調查發現地震災區中學生IBS患病率為23.6%；非地震災區患病率為21.6%，二者比較無統計學意義（P=0.267）；用羅馬Ⅲ標準調查發現地震災區中學生IBS患病率為6.2%，非地震災區患病率為4.6%，二者比較無統計學意義（P=0.139）。符合兩種診斷標準的地震災區IBS學生有10.3%，非地震災區IBS學生有9.2%，兩者差異無統計學意義（P＞0.05）。②支持兩種診斷標準的癥狀方面，地震災區IBS學生每天排便＞3次或每周排便＜3次等癥狀相比較有統計學意義（P＜0.001）。③按羅馬Ⅲ標準，各亞型構成比IBS-C為30.4%，IBS-D為28.4%，IBS-M為8.8%，IBS-U為32.4%；按羅馬Ⅱ標準，各亞型構成比為IBS-C為28.5%，IBS-D為47.7%，腹瀉和便秘交替型為18.6%，羅馬Ⅲ標準中的IBS-M和IBS-U合為一組與羅馬Ⅱ標準中的腹瀉和便秘交替型的構成比進行比較，二者有統計學意義（P＜0.001）。結論　羅馬Ⅱ和羅馬Ⅲ兩種標準調查地震災區中學生IBS患病率和分型存在著差異，但兩種標準對地震災區IBS患病率的影響是對等的，患病率和分型的不同是由兩種標準的本身的差異造成，可能更接近羅馬Ⅲ診斷標準。

Citation： ZHENG Shicheng,FU Wanchao,HE Ying,DONG Xiaowei,WANG Yiping,ZHANG Qiang.. Influence of Different Diagnostic Standards on the Prevalence of Irritable Bowel Syndrome among Middle School Students in Areas Affected by Wenchuan Earthquake. West China Medical Journal, 2012, 27(11): 1610-1613. doi: Copy

1.	Zhong L, Hou X. Pathophysiologic findings of irritable bowel syndrome in China[J]. J Neurogastroenterol Motil, 2012, 18(1): 19-33.
2.	Hungin AP, Whorwell PJ, Tack J, et al. The prevalence, patterns and impact of irritable bowel syndrome: an international survey of 40,000 subjects[J]. Aliment Pharmacol Ther, 2003, 17(5): 643-650.
3.	Zhou H, Yao M, Cheng GY, et al. Prevalence and associated factors of functional gastrointestinal disorders and bowel habits in Chinese adolescents: a school-based study[J]. J Pediatr Gastroenterol Nutr, 2011, 53(2): 168-173.
4.	袁帥, 張莉玲. 羅馬Ⅲ標準在腸易激綜合征診斷中的風險研究(附132例報告)[J]. 新醫學, 2009, 40(6): 391-392.
5.	Ersryd A, Posserud I, Abrahamsson H, et al. Subtyping the irritable bowel syndrome by predominant bowel habit: Rome Ⅱ versus Rome Ⅲ[J]. Aliment Pharmaeol Ther, 2007, 26(6): 953-961.
6.	Sperber AD, Shvartzman P, Friger M, et al. A comparative reappraisal of the RomeⅡ and RomeⅢ diagnostic criteria:are we getting closer to the ‘true’ prevalence of irritable bowel syndrome? [J]. Eur J Gastroenterol Hepatol, 2007(19): 441-447.
7.	胡品津, 方秀才. 腸易激綜合征診斷和治療[M]. 北京: 科學出版社, 2009: 47-48.
8.	Drossman DA. RomeⅢ: the functional gastrointestinal disorders[M]. 3rd ed. McLean: Degnon Associates Inc, 2006: 1-26.
9.	Zheng S, Fu W, Zhou J, et al. Prevalence and related factors of irritable bowel syndrome among middle-school students in areas affected by Wenchuan Earthquake: an epidemiological study[J]. J Clin Gastroenterol, 2012, 46(4): 345-346.
10.	周惠清, 李定國, 宋艷艷, 等. 青少年腸易激綜合征調查表的制定及考評[J]. 中華消化雜志, 2006, 26(2): 80-82.
11.	姚敏, 陳燕萍, 周惠清, 等. 我國南方青少年腸易激綜合征流行病學調查[J]. 臨床兒科雜志, 2007, 25(10): 835-839.
12.	王睿, 鄭仕誠, 張強, 等. 青少年焦慮情緒障礙篩查表在汶川地震災區中學生應用的信效度評價[J]. 四川大學學報(醫學版), 2012, 43(4): 562-565.
13.	陳志君, 高福音. 腸易激綜合征羅馬Ⅱ與羅馬Ⅲ標準在臨床應用中的比較研究[J]. 中國藥物與臨床, 2010, 10(11): 1270-1271.
14.	汪安江, 廖獻花, 胡品津, 等. 羅馬Ⅲ和羅馬Ⅱ標準診斷腸易激綜合征的比較[J]. 中華內科雜志, 2007, 46(8): 64-67.
15.	孫菁, 袁耀宗. 腸易激綜合征: 羅馬Ⅲ標準與我國共識意見解讀[J]. 醫學與哲學(臨床決策論壇版), 2008, 29(6): 12-14.
16.	Engsbro AL, Simren M, Bytzer P. Short-term stability of subtypes in the irritable bowel syndrome: prospective evaluation using the Rome Ⅲ classification[J]. Aliment Pharmacol Ther, 2012, 35(3): 350-359.
17.	Yao X, Yang YS, Cui LH, et al. Subtypes of irritable bowel syndrome on RomeⅢ criteria : a multi-center study[J]. J Gastroenterol Hepatol, 2011, 27(4):760-765.
18.	Ebling B, Jurci? D, Gmajni? R, et al. Anthropological, demographic and socioeconomic characteristics of irritable bowel syndrome[J]. Coll Antropol, 2011, 35(2): 513-521.
19.	Drossman DA, Chang L, Bellamy N, et al. Severity in irritable bowel syndrome: a Rome Foundation Working Team report[J]. Am J Gastroenterol, 2011, 106(10): 1749-1759.

1. 　Zhong L, Hou X. Pathophysiologic findings of irritable bowel syndrome in China[J]. J Neurogastroenterol Motil, 2012, 18(1): 19-33.
2. 　Hungin AP, Whorwell PJ, Tack J, et al. The prevalence, patterns and impact of irritable bowel syndrome: an international survey of 40,000 subjects[J]. Aliment Pharmacol Ther, 2003, 17(5): 643-650.
3. 　Zhou H, Yao M, Cheng GY, et al. Prevalence and associated factors of functional gastrointestinal disorders and bowel habits in Chinese adolescents: a school-based study[J]. J Pediatr Gastroenterol Nutr, 2011, 53(2): 168-173.
4. 　袁帥, 張莉玲. 羅馬Ⅲ標準在腸易激綜合征診斷中的風險研究(附132例報告)[J]. 新醫學, 2009, 40(6): 391-392.
5. 　Ersryd A, Posserud I, Abrahamsson H, et al. Subtyping the irritable bowel syndrome by predominant bowel habit: Rome Ⅱ versus Rome Ⅲ[J]. Aliment Pharmaeol Ther, 2007, 26(6): 953-961.
6. 　Sperber AD, Shvartzman P, Friger M, et al. A comparative reappraisal of the RomeⅡ and RomeⅢ diagnostic criteria:are we getting closer to the ‘true’ prevalence of irritable bowel syndrome? [J]. Eur J Gastroenterol Hepatol, 2007(19): 441-447.
7. 　胡品津, 方秀才. 腸易激綜合征診斷和治療[M]. 北京: 科學出版社, 2009: 47-48.
8. 　Drossman DA. RomeⅢ: the functional gastrointestinal disorders[M]. 3rd ed. McLean: Degnon Associates Inc, 2006: 1-26.
9. 　Zheng S, Fu W, Zhou J, et al. Prevalence and related factors of irritable bowel syndrome among middle-school students in areas affected by Wenchuan Earthquake: an epidemiological study[J]. J Clin Gastroenterol, 2012, 46(4): 345-346.
10. 　周惠清, 李定國, 宋艷艷, 等. 青少年腸易激綜合征調查表的制定及考評[J]. 中華消化雜志, 2006, 26(2): 80-82.
11. 　姚敏, 陳燕萍, 周惠清, 等. 我國南方青少年腸易激綜合征流行病學調查[J]. 臨床兒科雜志, 2007, 25(10): 835-839.
12. 　王睿, 鄭仕誠, 張強, 等. 青少年焦慮情緒障礙篩查表在汶川地震災區中學生應用的信效度評價[J]. 四川大學學報(醫學版), 2012, 43(4): 562-565.
13. 　陳志君, 高福音. 腸易激綜合征羅馬Ⅱ與羅馬Ⅲ標準在臨床應用中的比較研究[J]. 中國藥物與臨床, 2010, 10(11): 1270-1271.
14. 　汪安江, 廖獻花, 胡品津, 等. 羅馬Ⅲ和羅馬Ⅱ標準診斷腸易激綜合征的比較[J]. 中華內科雜志, 2007, 46(8): 64-67.
15. 　孫菁, 袁耀宗. 腸易激綜合征: 羅馬Ⅲ標準與我國共識意見解讀[J]. 醫學與哲學(臨床決策論壇版), 2008, 29(6): 12-14.
16. 　Engsbro AL, Simren M, Bytzer P. Short-term stability of subtypes in the irritable bowel syndrome: prospective evaluation using the Rome Ⅲ classification[J]. Aliment Pharmacol Ther, 2012, 35(3): 350-359.
17. 　Yao X, Yang YS, Cui LH, et al. Subtypes of irritable bowel syndrome on RomeⅢ criteria : a multi-center study[J]. J Gastroenterol Hepatol, 2011, 27(4):760-765.
18. 　Ebling B, Jurci? D, Gmajni? R, et al. Anthropological, demographic and socioeconomic characteristics of irritable bowel syndrome[J]. Coll Antropol, 2011, 35(2): 513-521.
19. 　Drossman DA, Chang L, Bellamy N, et al. Severity in irritable bowel syndrome: a Rome Foundation Working Team report[J]. Am J Gastroenterol, 2011, 106(10): 1749-1759.

West China Medical Journal

Influence of Different Diagnostic Standards on the Prevalence of Irritable Bowel Syndrome among Middle School Students in Areas Affected by Wenchuan Earthquake

Abstract Full text Figures/Tables Video References Cited by

Format

Content