Objective To study the effect of Bi Yuan Shu Liquid on melioration of clinical symptoms and signs of chronic nasal sinusitis or nasal polyp patients after Functional Endosoopic Sinus Surgery (FESS), and discuss the effectiveness of Chinese composite medicine in the overall treatment after FESS.
Methods A total of 340 patients were randomly allocated to treatment group (n =170) and control group (n =170) according to simple randomization procedure. Patients in treatment group were administrated with quinolone, steroid, and Bi Yuan Shu Liquid, which were compared with those in control group who were given quinolone and steroid.
Results The apparent effect of treatment group and control group were 30.6% and 42.4% of 42.4% of ITT. Results by Wilcoxon signed rank test indicated that there was a statistically significant difference.
Conclusions Bi Yuan Shu Liquid may improve the effectiveness of sinus surgery, reduce the time course of antibiotics and hormones, and with out toxicity and side-effect.
Citation：
LIANG Chuanyu,WEN Pei,ZHEN Yan,HE Gang,FAN Ming,LI Wanrong,TANG Siquan,PENG Tao,LIANG Guoqing,WANG Jie,ZHANG Yuping. Multi-Centre Randomized Controlled Trial of Bi Yuan Shu Liquid on Patients with Chronic Nasal Sinusitis or Nasal Polyp after Endosoopic Sinus Surgery. Chinese Journal of Evidence-Based Medicine, 2004, 04(6): 377-381. doi:
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Copyright ? the editorial department of Chinese Journal of Evidence-Based Medicine of West China Medical Publisher. All rights reserved
| 1. |
［1］Zhang NZ, Xia LJ. Observe after FESS for adult and children who suffer from chronic sinusitis by using Bi Yuan Shu Liquid[J ]. China J Otolaryngol Ingegrat Trad&West Medi (special publication), 2001; 12(9): 10-12.
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| 2. |
張念祖,夏立軍.鼻淵舒對成人、兒童慢性鼻竇炎與內窺鏡鼻竇手術后的應用觀察[J].中國中西醫結合耳鼻咽喉科雜志,2001;12(9專刊):10～12.
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| 3. |
［2］Multi-center, random,parallel and contrast Clinical research staard for treating nose-Antral inflammation with GG ( glucocorticoid) and evaluating its effect and safty [ R]. ENT department of CMA (China Medical Association). 2001.
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| 4. |
鼻用糖皮質激素治療鼻--鼻竇炎療效和安全性評價之多中心、隨機、平行對照臨床研究標準[R].中華醫學會耳鼻咽喉科分會.2001.
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| 5. |
［3］ENT department of CMA ( China Medical Association), Editorial Committee of China J Otolaryngol Medi. Clinical type and period of chronic sinusitis and nasal polyp &stadard of FESS (functional endoscopic sinus surgery) evaluation [J]. China J Otolaryngol Medicine, 1998; 33 (2): 133.
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| 6. |
中華醫學會耳鼻咽喉科分會,中華耳鼻咽喉科雜志編輯委員會.慢性鼻竇炎鼻息肉臨床分型分期及內窺鏡鼻竇手術療效評定標準[J].中華耳鼻咽喉科雜志,1998;33(2):133.
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| 7. |
［4］Chen LQ. Curative effectual observation of rhinitis and sinusits by using Bi Yuan Shu Liquid [ J ]. China J Otolaryngol Ingegrat Trad&West Medi ( special publication), 2001; 12 ( 9 ):23-24.
|
| 8. |
陳綠琦.鼻淵舒治療鼻炎鼻竇炎療效觀察[J].中國中西醫結合耳鼻咽喉科雜志,2001;12(9專刊):23～24.
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- 1. ［1］Zhang NZ, Xia LJ. Observe after FESS for adult and children who suffer from chronic sinusitis by using Bi Yuan Shu Liquid[J ]. China J Otolaryngol Ingegrat Trad&West Medi (special publication), 2001; 12(9): 10-12.
- 2. 張念祖,夏立軍.鼻淵舒對成人、兒童慢性鼻竇炎與內窺鏡鼻竇手術后的應用觀察[J].中國中西醫結合耳鼻咽喉科雜志,2001;12(9專刊):10～12.
- 3. ［2］Multi-center, random,parallel and contrast Clinical research staard for treating nose-Antral inflammation with GG ( glucocorticoid) and evaluating its effect and safty [ R]. ENT department of CMA (China Medical Association). 2001.
- 4. 鼻用糖皮質激素治療鼻--鼻竇炎療效和安全性評價之多中心、隨機、平行對照臨床研究標準[R].中華醫學會耳鼻咽喉科分會.2001.
- 5. ［3］ENT department of CMA ( China Medical Association), Editorial Committee of China J Otolaryngol Medi. Clinical type and period of chronic sinusitis and nasal polyp &stadard of FESS (functional endoscopic sinus surgery) evaluation [J]. China J Otolaryngol Medicine, 1998; 33 (2): 133.
- 6. 中華醫學會耳鼻咽喉科分會,中華耳鼻咽喉科雜志編輯委員會.慢性鼻竇炎鼻息肉臨床分型分期及內窺鏡鼻竇手術療效評定標準[J].中華耳鼻咽喉科雜志,1998;33(2):133.
- 7. ［4］Chen LQ. Curative effectual observation of rhinitis and sinusits by using Bi Yuan Shu Liquid [ J ]. China J Otolaryngol Ingegrat Trad&West Medi ( special publication), 2001; 12 ( 9 ):23-24.
- 8. 陳綠琦.鼻淵舒治療鼻炎鼻竇炎療效觀察[J].中國中西醫結合耳鼻咽喉科雜志,2001;12(9專刊):23～24.
