Correlation Analysis of Risk Factors in Patients with Post-menopause Osteoporosis_Chinese Journal of Evidence-Based Medicine

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Yueyang Hospital Affiliated to the Shanghai University of TCM, Shanghai 200437, China;

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Keywords：

Primary osteoporosis; Risk factors; Correlation Analysis

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Objective 　To explore the correlation of risk factors affecting the L2-4BMD level in patients with post-menopausal osteoporosis.
Methods 　Ninety-two patients with post-menopausal osteoporosis were surveyed with a retrospective questionnaire. We used the findings to set up a multiple stepwise regression model and perform correlation analysis with L2-4BMD levels as the dependent variable and risk factors as the independent variables.
Results 　Assuming that age has a definite effect on the L2-4BMD level of menopausal women, menopausal age limit, history of milk drinking, menopausal age, menarche age, fracture history and bend-back entered into the multiple stepwise regression equation.
Conclusions 　Menopausal age limit, history of milk drinking, menopausal age, menarche age, fracture history, and bend-back influence patients with menopausal osteoporosis.The menopausal age limit is especially important. Awareness of the risk factors of osteoporosis should be raised.

Citation： SHI Xiao,YANG Wenhong. Correlation Analysis of Risk Factors in Patients with Post-menopause Osteoporosis. Chinese Journal of Evidence-Based Medicine, 2006, 06(10): 756-759. doi: Copy

1.	中國老年學學會骨質疏松委員會骨質疏松診斷標準學科組.中國人原發性骨質疏松癥診斷標準(試行).中國骨質疏松雜志, 1999; 5(1): 1–3.
2.	蔣鳳艷，勞山，龍鳳宜等.年齡、絕經年限與骨代謝指標相關性研究.實用婦產科雜志, 2003; 19(2): 91–92.
3.	楊定焯, 楊惠, 劉芳, 等. 力學負荷對峰值骨量影響的初步研究. 中國骨質疏松雜志, 2003; 9(2): 124–127.
4.	樸俊紅, 龐蓮萍, 劉忠厚, 等. 中國人口狀況及原發性骨質疏松癥診斷標準和發生率. 中國骨質疏松雜志, 2002; 8(1): 1–7.
5.	黃干, 廖二元, 伍賢平, 等. 老年婦女體重指數與骨密度和骨超聲傳導速度的相關性研究. 中華物理醫學與康復雜志, 2003; 25(1): 23–26.
6.	劉建民, 趙紅燕, 寧光等. 絕經前健康婦女的身體組成成分與骨密度的關系. 中國醫學科學院學報, 2003; 25(3): 250–253.
7.	Diagnosis guideline of Chinese primary osteoporosis (temporary). Chinese geraeology academy, Osteoporosis committee. Diagnosis standard groupof osteoporosis.Chinese Journal of Osteoporosis, 1999; 5(1): 1–3.
8.	Fujta Y, Katsumata K, Unno A, et al. Factors affecting peak bone density in Japanese women. Calcif tissue Int, 1999; 64(2): 107–111.
9.	Jiang FY, Lao San, Long FY, et al. Study on Correlation Among Age,Menopausal Years and Bone Metabolite Index. Journal of Practical Obstetrics and Gynecology, 2003; 19(2): 91–92.
10.	Yang DZ, Yang Hui, Liu Fang, et al. Effects of mechanical load on peak bone mass. Chinese Journal of Osteoporosis, 2003,9（2）：124–127.
11.	Trivitayaratana,-W; rivitayaratana, -P. Limb measurements for height and bone mineral density estimation. J-Med-Assoc-Thai, 2001; 84(2):S505–509.
12.	Versluis RG, Papapoulos SE. Clinical risk factors as predictors of postmenopausal osteoporosis in general practice. Br-J-Gen-Pract，2001; 51(471): 806–810.
13.	Piao JH, Pang LP, Liu ZH, et al. Chinese population, the diagnostic criteria of primary osteoporosis and the incidence of osteoporosis in china. Chinese Journal of Osteoporosis, 2002; 8(1): 1–7.
14.	Nourhashemi F，Rolland Y，Vellas B．Prevention of falls and their consequence. Presse Med, 2000; 29: 1249–1254.
15.	Runge M. Diagnosis of the risk of accidental falls in the eldedy. Ther Umsch, 2002; 59: 351–358．.
16.	Parkkari J, Kannus P, Palvanen M, et al. Majority of hip fractures occur as a result of a fall and impact on the greater trochanter of the femur: a prospective controlled hip fracture study with 206 consecutive patients. Calcif Tissue Int, 1999; 65: 183–187.
17.	Grabiner MD, Pavol MJ, Owings TM. Can fall-related hip fractures be prevented by characterizing the biomechanical mechanisms of failed recovery? Endocrine, 2002; 17: 15–20.
18.	Teegarden D, Lyle RM, Proulx WR, et a1. Previous milk consumption associated with greater bone density in young women. Am J Clin Nutr, 1999; 69: 1014–1017.
19.	Bonjour JP, Chevalley T, Ammann P, et a1．Gain in bone mineral mass in prepubertal girls 3.5 years after discontinuation of calcium supplementation: a follow-up study. Lancet, 2001; 358: 1208–1212.
20.	Reid IR, Ames RW, Evans MC, et a1. Long-term effects of calcium supplementation on bone loss and fractures in postmenopausual women: a randomized controlled trial. Am J Med, 1995; 98: 331–335.
21.	Huang G, Liao ey, Wu XP, et al. The relationship between body mass index and bone mineral density and conduction velocity of sound in bone in elderly women. Chinese Journal of Physical Medicine and Retabulitation, 2003; 25(1): 23–26.
22.	Fox MX, Magaziner J, Hawkes WG, et al. Loss of bone density and lean body mass after hip fracture. Osteoporos Int, 2000; 11: 31–35.
23.	Liu JM, Zhao HY, Ning G, et al. Relationship between Body Composition and Bone Mineral Density in Healthy Premenopausal Women. Acta Academiae Medicinae Sinicae, 2003; 25(3):250-253.

1. 中國老年學學會骨質疏松委員會骨質疏松診斷標準學科組.中國人原發性骨質疏松癥診斷標準(試行).中國骨質疏松雜志, 1999; 5(1): 1–3.
2. 蔣鳳艷，勞山，龍鳳宜等.年齡、絕經年限與骨代謝指標相關性研究.實用婦產科雜志, 2003; 19(2): 91–92.
3. 楊定焯, 楊惠, 劉芳, 等. 力學負荷對峰值骨量影響的初步研究. 中國骨質疏松雜志, 2003; 9(2): 124–127.
4. 樸俊紅, 龐蓮萍, 劉忠厚, 等. 中國人口狀況及原發性骨質疏松癥診斷標準和發生率. 中國骨質疏松雜志, 2002; 8(1): 1–7.
5. 黃干, 廖二元, 伍賢平, 等. 老年婦女體重指數與骨密度和骨超聲傳導速度的相關性研究. 中華物理醫學與康復雜志, 2003; 25(1): 23–26.
6. 劉建民, 趙紅燕, 寧光等. 絕經前健康婦女的身體組成成分與骨密度的關系. 中國醫學科學院學報, 2003; 25(3): 250–253.
7. Diagnosis guideline of Chinese primary osteoporosis (temporary). Chinese geraeology academy, Osteoporosis committee. Diagnosis standard groupof osteoporosis.Chinese Journal of Osteoporosis, 1999; 5(1): 1–3.
8. Fujta Y, Katsumata K, Unno A, et al. Factors affecting peak bone density in Japanese women. Calcif tissue Int, 1999; 64(2): 107–111.
9. Jiang FY, Lao San, Long FY, et al. Study on Correlation Among Age,Menopausal Years and Bone Metabolite Index. Journal of Practical Obstetrics and Gynecology, 2003; 19(2): 91–92.
10. Yang DZ, Yang Hui, Liu Fang, et al. Effects of mechanical load on peak bone mass. Chinese Journal of Osteoporosis, 2003,9（2）：124–127.
11. Trivitayaratana,-W; rivitayaratana, -P. Limb measurements for height and bone mineral density estimation. J-Med-Assoc-Thai, 2001; 84(2):S505–509.
12. Versluis RG, Papapoulos SE. Clinical risk factors as predictors of postmenopausal osteoporosis in general practice. Br-J-Gen-Pract，2001; 51(471): 806–810.
13. Piao JH, Pang LP, Liu ZH, et al. Chinese population, the diagnostic criteria of primary osteoporosis and the incidence of osteoporosis in china. Chinese Journal of Osteoporosis, 2002; 8(1): 1–7.
14. Nourhashemi F，Rolland Y，Vellas B．Prevention of falls and their consequence. Presse Med, 2000; 29: 1249–1254.
15. Runge M. Diagnosis of the risk of accidental falls in the eldedy. Ther Umsch, 2002; 59: 351–358．.
16. Parkkari J, Kannus P, Palvanen M, et al. Majority of hip fractures occur as a result of a fall and impact on the greater trochanter of the femur: a prospective controlled hip fracture study with 206 consecutive patients. Calcif Tissue Int, 1999; 65: 183–187.
17. Grabiner MD, Pavol MJ, Owings TM. Can fall-related hip fractures be prevented by characterizing the biomechanical mechanisms of failed recovery? Endocrine, 2002; 17: 15–20.
18. Teegarden D, Lyle RM, Proulx WR, et a1. Previous milk consumption associated with greater bone density in young women. Am J Clin Nutr, 1999; 69: 1014–1017.
19. Bonjour JP, Chevalley T, Ammann P, et a1．Gain in bone mineral mass in prepubertal girls 3.5 years after discontinuation of calcium supplementation: a follow-up study. Lancet, 2001; 358: 1208–1212.
20. Reid IR, Ames RW, Evans MC, et a1. Long-term effects of calcium supplementation on bone loss and fractures in postmenopausual women: a randomized controlled trial. Am J Med, 1995; 98: 331–335.
21. Huang G, Liao ey, Wu XP, et al. The relationship between body mass index and bone mineral density and conduction velocity of sound in bone in elderly women. Chinese Journal of Physical Medicine and Retabulitation, 2003; 25(1): 23–26.
22. Fox MX, Magaziner J, Hawkes WG, et al. Loss of bone density and lean body mass after hip fracture. Osteoporos Int, 2000; 11: 31–35.
23. Liu JM, Zhao HY, Ning G, et al. Relationship between Body Composition and Bone Mineral Density in Healthy Premenopausal Women. Acta Academiae Medicinae Sinicae, 2003; 25(3):250-253.

Chinese Journal of Evidence-Based Medicine

Correlation Analysis of Risk Factors in Patients with Post-menopause Osteoporosis

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