成人先天性肺氣道畸形一例_Chinese Journal of Respiratory and Critical Care Medicine

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徐志強 , 梁宗安

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先天性肺氣道畸形

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臨床資料 患者男性, 38 歲。主因“咳嗽, 咯痰, 活動后氣促3 年, 加重6 個月”入院。3 年前患者于天氣變化受涼感冒后出現咳嗽, 咯少量痰, 自覺發熱, 當時未測體溫, 無胸
悶、氣促、喘息、胸痛、潮熱、盜汗。3 年來患者易感冒, 活動后氣促, 活動耐量下降, 但無咯血、消瘦、雙下肢水腫等, 夜間喜高枕位休息, 曾在當地醫院診為肺結核, 行抗結核治療7個月癥狀無好轉。6 個月前患者出現持續性咳嗽, 咯少量痰, 活動后氣促明顯, 無潮熱、盜汗、消瘦等, 仍診斷“肺結核”, 予口服異煙肼、利福噴丁等藥物治療3 個月, 癥狀仍無緩解, 為進一步診治入我院。患者自15 歲后發現有“杵狀指”, 至本次發病期間無特殊變化。否認其他急慢性疾病史。從事工作為廢品回收, 無放射線、重金屬毒物接觸史。吸煙4 年, 20 支/d。家族史無特殊。‥‥‥

Citation： 徐志強,梁宗安. 成人先天性肺氣道畸形一例. Chinese Journal of Respiratory and Critical Care Medicine, 2010, 9(2): 202-204. doi: Copy

1.	Clements BS. Congenital malformations of the lungs and airways. In:Taussig LM, Landau LI. Pediatric respiratory medicine. St Louis:Mosby, 1999, 1106-1136.
2.	Ch′in KY, Tang MY. Congenital adenomatoid malformation of one　lobe of a lung with general anasarca. Arch Pathol ( Chic) , 1949, 48 :221-229.
3.	Heling KS, Tennstedt C, Chaoui R. Unusual case of a fetus with　congenital cystic adenomatoid malformation of the lung associated　with trisomy 13. Prenat Diagn, 2003 , 23: 315-318.
4.	Lantuejoul S, Nicholson AG, Sartori G, et al Mucinous cells in type　1 pulmonary congenital cystic adenomatoid malformation as　mucinous bronchioloalveolar carcinoma precursors. Am J Surg　Pathol, 2007 , 31: 961 -969.
5.	Stocker JT, Madewell JE, Drake RM. Congenital cystic adenomatoid　malformation of the lung. Classification and morphologic spectrum.Hum Pathol, 1977, 8: 155 -171.
6.	Stocker JT. Congenital and developmental diseases. In: Pulmonary　pathology, Hammar SP, Ed. 1994, Springer-Verlag, New York, 155 -190.
7.	Zylak CJ, Eyler WR, Spizarny DL, et al. Developmental lung　anomalies in the adult: radiologic-pathologic correlation.Radiographics, 2002, 22: S25 -S43.
8.	Federici S, Domenichelli V, Tani G, et al. Pleuropulmonary blastoma　in congenital cystic adenomatoid malformation: report of a case. Eur　J Pediatr Surg, 2001, 11 : 196-199 .
9.	常占平, 金錦善, 金妍, 等. 成人肺先天性囊性腺瘤樣畸形伴發肺癌. 診斷病理學雜志, 2003, 10 : 284-286 .
10.	Kaslovsky RA, Purdy S, Dangman BC, et al. Bronchioloalveolar　carcinoma in a child with congenital cystic adenomatoid　malformation . Chest, 1997, 112: 548 -551.
11.	Benjamin DR, Cahill J. Bronchioloalveolar carcinoma of the lung and　congenital cystic adenomatoid malformation. Am J Clin Pathol,1991, 95: 889-892 .

1. Clements BS. Congenital malformations of the lungs and airways. In:Taussig LM, Landau LI. Pediatric respiratory medicine. St Louis:Mosby, 1999, 1106-1136.
2. Ch′in KY, Tang MY. Congenital adenomatoid malformation of one　lobe of a lung with general anasarca. Arch Pathol ( Chic) , 1949, 48 :221-229.
3. Heling KS, Tennstedt C, Chaoui R. Unusual case of a fetus with　congenital cystic adenomatoid malformation of the lung associated　with trisomy 13. Prenat Diagn, 2003 , 23: 315-318.
4. Lantuejoul S, Nicholson AG, Sartori G, et al Mucinous cells in type　1 pulmonary congenital cystic adenomatoid malformation as　mucinous bronchioloalveolar carcinoma precursors. Am J Surg　Pathol, 2007 , 31: 961 -969.
5. Stocker JT, Madewell JE, Drake RM. Congenital cystic adenomatoid　malformation of the lung. Classification and morphologic spectrum.Hum Pathol, 1977, 8: 155 -171.
6. Stocker JT. Congenital and developmental diseases. In: Pulmonary　pathology, Hammar SP, Ed. 1994, Springer-Verlag, New York, 155 -190.
7. Zylak CJ, Eyler WR, Spizarny DL, et al. Developmental lung　anomalies in the adult: radiologic-pathologic correlation.Radiographics, 2002, 22: S25 -S43.
8. Federici S, Domenichelli V, Tani G, et al. Pleuropulmonary blastoma　in congenital cystic adenomatoid malformation: report of a case. Eur　J Pediatr Surg, 2001, 11 : 196-199 .
9. 常占平, 金錦善, 金妍, 等. 成人肺先天性囊性腺瘤樣畸形伴發肺癌. 診斷病理學雜志, 2003, 10 : 284-286 .
10. Kaslovsky RA, Purdy S, Dangman BC, et al. Bronchioloalveolar　carcinoma in a child with congenital cystic adenomatoid　malformation . Chest, 1997, 112: 548 -551.
11. Benjamin DR, Cahill J. Bronchioloalveolar carcinoma of the lung and　congenital cystic adenomatoid malformation. Am J Clin Pathol,1991, 95: 889-892 .

Chinese Journal of Respiratory and Critical Care Medicine

成人先天性肺氣道畸形一例

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