A scoping review of the core outcome set research in traditional Chinese medicine_Chinese Journal of Evidence-Based Medicine

Authors：

QIU Xingying ¹ , TANG Qi ¹ , CAO Wencong ¹ , LIU Bingqing ¹ ,  WEN Zehuai ^2,3,4 ,  LI Geng ^2,3

1. The Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510405, P. R. China;
2. State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, P. R. China;
3. Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, P. R. China;
4. Science and Technology Innovation Center, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, P. R. China;

Corresponding?author：

WEN Zehuai, Email: wenzh@gzucm.edu.cn; LI Geng, Email: ligeng@gzucm.edu.cn

Keywords：

Traditional Chinese medicine; Core outcome set; Scoping review

DOI：

10.7507/1672-2531.202306122

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To summarize the current studies of the core outcome set of traditional Chinese medicine (COS-TCM) and analyze their possible problems. Methods The CNKI, WanFang Data, VIP, PubMed, Web of Science, Embase, and Cochrane Library databases were electronically searched to collect studies from inception to April 18, 2023. The relevant characteristics of the included studies were extracted, and the development steps, stakeholders, and outcomes of COS-TCM were analyzed. Results A total of 28 COS-TCM studies were included. Two studies, only published systematic reviews without providing more information, were excluded from the analysis. Among the 26 studies for analysis, 25 studies (96.15%) used a mixture of methods to develop COS-TCM. Clinicians (n=25) were the most common participants, followed by methodologists and patients. Fifteen studies (57.69%) reported measures to help patients better participate. Twelve consensus definitions were found in the included studies, of which 14 studies' consensus definitions were divided into three levels:"consensus in", "consensus out", and "no consensus". Among the 14 studies that reported the final COS-TCM results, only 4 studies recommended Chinese medicine characteristic outcomes. For the measurement of outcomes, 14 studies (53.85%) made plans for the selection of tools. Conclusion The current COS-TCM research has made some progress, and the common developing methods are roughly the same as those nationally used. However, there are still some problems, such as inadequate and low-transparency reports, lack of TCM characteristic outcomes, and so on. We suggest that future COS-TCM studies should refer to COS-STAP, COS-STAR, COS-STAD, and other international standards as well as emphasize the advantages of TCM during development and reporting so that it can improve the transparency of developing methods, research quality, and the proportion of TCM characteristics of the final COS.

Citation： QIU Xingying, TANG Qi, CAO Wencong, LIU Bingqing, WEN Zehuai, LI Geng. A scoping review of the core outcome set research in traditional Chinese medicine. Chinese Journal of Evidence-Based Medicine, 2023, 23(12): 1419-1427. doi: 10.7507/1672-2531.202306122 Copy

1.	符宇, 邵明義, 趙瑞霞, 等. 基于中醫證據的中醫臨床療效評價方法探討. 中醫雜志, 2020, 61(13): 1124-1129.
2.	趙瓊, 張俊龍, 竇志芳. 中醫療效評價的現狀分析與解決思路探析. 中華中醫藥雜志, 2023, 38(2): 772-774.
3.	代欣玥, 訾明杰, 楊巧寧, 等. 基于文獻的中醫藥臨床研究結局指標現狀分析及思考. 中醫雜志, 2022, 63(12): 1122-1127.
4.	Williamson PR, Altman DG, Blazeby JM, et al. Developing core outcome sets for clinical trials: issues to consider. Trials, 2012, 13: 132.
5.	邢冬梅, 張俊華, 張伯禮. 中醫臨床研究核心結局指標集形成路徑. 中華中醫藥雜志, 2014, 29(5): 1352-1355.
6.	COMET Initiative. Core outcome set for stable angina pectoris in traditional Chinese medicine (COS-SAP-TCM).
7.	Zhang L, Zhang J, Chen J, et al. Clinical research of traditional Chinese medicine needs to develop its own system of core outcome sets. Evid Based Complement Alternat Med, 2013, 2013: 202703.
8.	邱瑞瑾, 魏旭煦, 關之玥, 等. 中醫藥領域核心指標集研究現狀及展望. 中國循證醫學雜志, 2023, 23(2): 211-220.
9.	Gargon E, Gorst SL, Matvienko-Sikar K, et al. Choosing important health outcomes for comparative effectiveness research: 6th annual update to a systematic review of core outcome sets for research. PLoS One, 2021, 16(1): e0244878.
10.	卞薇, 陳慧, 宋國敏, 等. 概況性評價簡介. 中國循證醫學雜志, 2017, 17(4): 488-493.
11.	孫亞男, 于長禾, 楊洋, 等. 基于系統評價與專家共識建立中醫治療乙肝的核心結局指標集: 方案. 沈陽: 世界中聯倫理審查委員會第四屆學術年會暨世界中聯臨床療效評價專業委員會第八屆學術年會, 2014.
12.	李凱, 張俊華, 蔡慧姿, 等. 中藥注射劑治療非小細胞肺癌臨床試驗結局指標文獻研究. 天津中醫藥, 2021, 38(2): 209-212.
13.	王子衿, 孫偉偉, 張穎思, 等. 中醫藥治療子宮內膜異位癥隨機對照試驗結局指標與測量工具的現狀分析. 中國中藥雜志, 2023, 48(16): 4521-4528.
14.	楊繼, 張垚, 張運嬌, 等. 基于主成分分析的中醫藥治療慢性心力衰竭臨床隨機對照試驗核心結局指標研究. 中西醫結合心腦血管病雜志, 2021, 19(15): 2496-2509, 2515.
15.	Qiu R, Han S, Wei X, et al. Development of a core outcome set for the benefits and adverse events of acute heart failure in clinical trials of traditional Chinese medicine and Western medicine: a study protocol. Front Med (Lausanne), 2021, 8: 677068.
16.	Qiu R, Zhong C, Wan S, et al. Developing a core outcome set for assessing clinical safety outcomes of cardiovascular diseases in clinical trials of integrated traditional Chinese medicine and Western medicine: study protocol. Trials, 2022, 23(1): 239.
17.	Jin X, Pang B, Zhang J, et al. Core outcome set for clinical trials on coronavirus disease 2019 (COS-COVID). Engineering (Beijing), 2020, 6(10): 1147-1152.
18.	Qiu R, Zhao C, Liang T, et al. Core outcome set for clinical trials of COVID-19 based on traditional Chinese and Western medicine. Front Pharmacol, 2020, 11: 781.
19.	孫亞男, 何麗云, 雒琳, 等. 中醫藥治療慢性乙型肝炎臨床試驗的核心結局指標集研究. 中華中醫藥雜志, 2020, 35(9): 4684-4688.
20.	萬穎. 慢性腰痛中醫臨床研究核心結局指標集的構建. 北京: 北京中醫藥大學, 2021.
21.	Qiu R, Zhong C, Han S, et al. Development of a core outcome set for myocardial infarction in clinical trials of traditional Chinese medicine: a study protocol. BMJ Open, 2019, 9(12): e032256.
22.	Zhang M, Zhang J, Chua H, et al. Core outcome set for stable angina pectoris in traditional Chinese medicine (COS-SAP-TCM). Acupunct Herb Med, 2021, 1(1): 39-48.
23.	白楊, 宏亞麗, 陳波, 等. 針灸治療粘連性肩關節囊炎臨床研究核心結局指標集的構建方法. 中國針灸, 2023, 43(6): 701-705.
24.	謝倩文, 肖晶旻, 鄧雪儀, 等. 建立中醫藥治療缺血性卒中核心結局指標集的初步研究. 中醫雜志, 2022, 63(3): 220-228.
25.	嵇鑫陳. 中醫藥治療重癥肌無力的臨床研究核心指標集構建研究. 長春: 長春中醫藥大學, 2022.
26.	秦懿囡, 徐天宇, 李澤鑫, 等. 初步構建針刺治療特發性面神經麻痹核心結局指標集. 世界科學技術-中醫藥現代化, 2023, 25(3): 1069-1077.
27.	李心怡, 石兆峰, 胡嘉元, 等. 針刺治療偏頭痛核心結局指標集的建立. 世界科學技術-中醫藥現代化, 2020, 22(1): 7-12.
28.	李凱. 中醫藥治療肺癌核心指標集研究. 天津: 天津中醫藥大學, 2021.
29.	Sheng X, Chen C, Ji Z, et al. Development of a core outcome set on traditional Chinese medicine and Western medicine for rheumatic heart disease: a study protocol. BMJ Open, 2022, 12(11): e062497.
30.	Zhang T, Li X, Zhao L, et al. Development of a core outcome set in the clinical trials of traditional Chinese medicine for stroke: a study protocol. Front Med (Lausanne), 2022, 9: 753138.
31.	Zhang M, Chua HZ, Zhang J, et al. Developing a core outcome set on traditional Chinese medicine (COS-TCM) for chronic heart failure (CHF): a study protocol. BMJ Open, 2021, 11(7): e047148.
32.	Dai XY, Zi MJ, Liu CX, et al. Development of a core outcome set in the clinical trials of traditional Chinese medicine for diabetic foot: a study protocol. Front Med (Lausanne), 2022, 9: 1025833.
33.	Niu B, Zhang M, Chua HZ, et al. Treatment of chronic pulmonary heart disease with traditional Chinese medicine: a protocol for the development of a core outcome set (COS-TCM-CPHD). Evid Based Complement Alternat Med, 2021, 2021: 5559883.
34.	Li G, Han R, Lin M, et al. Developing a core outcome set for clinical trials of Chinese medicine for hyperlipidemia. Front Pharmacol, 2022, 13: 847101.
35.	Qiu R, Li M, Zhang X, et al. Development of a core outcome set (COS) and selecting outcome measurement instruments (OMIs) for non-valvular atrial fibrillation in traditional Chinese medicine clinical trials: study protocol. Trials, 2018, 19(1): 541.
36.	Liu M, Gao Y, Yuan Y, et al. Sjogren's syndrome in clinical trials of traditional Chinese medicine: protocol for the development of a core outcome set. Trials, 2021, 22(1): 233.
37.	Jia M, Lu Y, Liang X, et al. Development of a core outcome set for hypertensive intracerebral hemorrhage in clinical trials of traditional Chinese medicine: a study protocol. Trials, 2022, 23(1): 871.
38.	Dodd S, Clarke M, Becker L, et al. A taxonomy has been developed for outcomes in medical research to help improve knowledge discovery. J Clin Epidemiol, 2018, 96: 84-92, 96-84.
39.	Basch E, Reeve BB, Mitchell SA, et al. Development of the National Cancer Institute's patient-reported outcomes version of the common terminology criteria for adverse events (PRO-CTCAE). J Natl Cancer Inst, 2014, 106(9): dju244.
40.	張明妍, 張俊華, 張伯禮, 等. 中醫藥臨床試驗核心指標集研制技術規范. 中華中醫藥雜志, 2021, 36(2): 924-928.
41.	Williamson PR, Altman DG, Bagley H, et al. The COMET handbook: version 1. 0. Trials, 2017, 18(Suppl 3): 280.
42.	代欣玥. 中醫藥治療糖尿病足臨床研究核心指標集指標域構建研究. 北京: 中國中醫科學院, 2021.
43.	邱瑞瑾. 中醫臨床研究核心指標集的方法構建. 北京: 北京中醫藥大學, 2018.
44.	Gargon E, Crew R, Burnside G, et al. Higher number of items associated with significantly lower response rates in COS Delphi surveys. J Clin Epidemiol, 2019, 108: 108-120.
45.	Hall DA, Smith H, Heffernan E, et al. Recruiting and retaining participants in e-Delphi surveys for core outcome set development: Evaluating the COMiT'ID study. PLoS One, 2018, 13(7): e0201378.
46.	Fish R, MacLennan S, Alkhaffaf B, et al. "Vicarious thinking" was a key driver of score change in Delphi surveys for COS development and is facilitated by feedback of results. J Clin Epidemiol, 2020, 128: 118-129.
47.	Brookes ST, Macefield RC, Williamson PR, et al. Three nested randomized controlled trials of peer-only or multiple stakeholder group feedback within Delphi surveys during core outcome and information set development. Trials, 2016, 17(1): 409.
48.	Remus A, Smith V, Wuytack F. Methodology in core outcome set (COS) development: the impact of patient interviews and using a 5-point versus a 9-point Delphi rating scale on core outcome selection in a COS development study. BMC Med Res Methodol, 2021, 21(1): 10.
49.	Brookes ST, Chalmers KA, Avery KNL, et al. Impact of question order on prioritisation of outcomes in the development of a core outcome set: a randomised controlled trial. Trials, 2018, 19(1): 66.
50.	羅輝, 廖星, 王茜. 中醫證候積分在療效評價中的應用: 基于240項隨機對照試驗的比較研究. 中國中西醫結合雜志, 2015, 35(10): 1261-1266.
51.	陳智慧, 張會永, 裴宇鵬, 等. 基于中醫證候量表探討建立智能化中醫藥臨床決策與療效評價模式的設想. 北京中醫藥大學學報, 2021, 44(3): 221-225.
52.	Gorst SL, Prinsen CAC, Salcher-Konrad M, et al. Methods used in the selection of instruments for outcomes included in core outcome sets have improved since the publication of the COSMIN/COMET guideline. J Clin Epidemiol, 2020, 125: 64-75,125-164.
53.	Brunton G, Webbe J, Oliver S, et al. Adding value to core outcome set development using multimethod systematic reviews. Res Synth Methods, 2020, 11(2): 248-259.
54.	Kirkham JJ, Gorst S, Altman DG, et al. Core Outcome Set-STAndards for Reporting: the COS-STAR statement. PLoS Med, 2016, 13(10): e1002148.
55.	Kirkham JJ, Davis K, Altman DG, et al. Core Outcome Set-STAndards for Development: the COS-STAD recommendations. PLoS Med, 2017, 14(11): e1002447.
56.	Kirkham JJ, Gorst S, Altman DG, et al. Core Outcome Set-STAndardised Protocol items: the COS-STAP statement. Trials, 2019, 20(1): 116.
57.	邱瑞瑾, 胡嘉元, 李敏, 等. 核心指標集研究方案的標準報告條目解讀及不同核心指標集研究報告指南對中醫藥領域研究的意義. 中國循證醫學雜志, 2019, 19(12): 1492-1497.

1. 符宇, 邵明義, 趙瑞霞, 等. 基于中醫證據的中醫臨床療效評價方法探討. 中醫雜志, 2020, 61(13): 1124-1129.
2. 趙瓊, 張俊龍, 竇志芳. 中醫療效評價的現狀分析與解決思路探析. 中華中醫藥雜志, 2023, 38(2): 772-774.
3. 代欣玥, 訾明杰, 楊巧寧, 等. 基于文獻的中醫藥臨床研究結局指標現狀分析及思考. 中醫雜志, 2022, 63(12): 1122-1127.
4. Williamson PR, Altman DG, Blazeby JM, et al. Developing core outcome sets for clinical trials: issues to consider. Trials, 2012, 13: 132.
5. 邢冬梅, 張俊華, 張伯禮. 中醫臨床研究核心結局指標集形成路徑. 中華中醫藥雜志, 2014, 29(5): 1352-1355.
6. COMET Initiative. Core outcome set for stable angina pectoris in traditional Chinese medicine (COS-SAP-TCM).
7. Zhang L, Zhang J, Chen J, et al. Clinical research of traditional Chinese medicine needs to develop its own system of core outcome sets. Evid Based Complement Alternat Med, 2013, 2013: 202703.
8. 邱瑞瑾, 魏旭煦, 關之玥, 等. 中醫藥領域核心指標集研究現狀及展望. 中國循證醫學雜志, 2023, 23(2): 211-220.
9. Gargon E, Gorst SL, Matvienko-Sikar K, et al. Choosing important health outcomes for comparative effectiveness research: 6th annual update to a systematic review of core outcome sets for research. PLoS One, 2021, 16(1): e0244878.
10. 卞薇, 陳慧, 宋國敏, 等. 概況性評價簡介. 中國循證醫學雜志, 2017, 17(4): 488-493.
11. 孫亞男, 于長禾, 楊洋, 等. 基于系統評價與專家共識建立中醫治療乙肝的核心結局指標集: 方案. 沈陽: 世界中聯倫理審查委員會第四屆學術年會暨世界中聯臨床療效評價專業委員會第八屆學術年會, 2014.
12. 李凱, 張俊華, 蔡慧姿, 等. 中藥注射劑治療非小細胞肺癌臨床試驗結局指標文獻研究. 天津中醫藥, 2021, 38(2): 209-212.
13. 王子衿, 孫偉偉, 張穎思, 等. 中醫藥治療子宮內膜異位癥隨機對照試驗結局指標與測量工具的現狀分析. 中國中藥雜志, 2023, 48(16): 4521-4528.
14. 楊繼, 張垚, 張運嬌, 等. 基于主成分分析的中醫藥治療慢性心力衰竭臨床隨機對照試驗核心結局指標研究. 中西醫結合心腦血管病雜志, 2021, 19(15): 2496-2509, 2515.
15. Qiu R, Han S, Wei X, et al. Development of a core outcome set for the benefits and adverse events of acute heart failure in clinical trials of traditional Chinese medicine and Western medicine: a study protocol. Front Med (Lausanne), 2021, 8: 677068.
16. Qiu R, Zhong C, Wan S, et al. Developing a core outcome set for assessing clinical safety outcomes of cardiovascular diseases in clinical trials of integrated traditional Chinese medicine and Western medicine: study protocol. Trials, 2022, 23(1): 239.
17. Jin X, Pang B, Zhang J, et al. Core outcome set for clinical trials on coronavirus disease 2019 (COS-COVID). Engineering (Beijing), 2020, 6(10): 1147-1152.
18. Qiu R, Zhao C, Liang T, et al. Core outcome set for clinical trials of COVID-19 based on traditional Chinese and Western medicine. Front Pharmacol, 2020, 11: 781.
19. 孫亞男, 何麗云, 雒琳, 等. 中醫藥治療慢性乙型肝炎臨床試驗的核心結局指標集研究. 中華中醫藥雜志, 2020, 35(9): 4684-4688.
20. 萬穎. 慢性腰痛中醫臨床研究核心結局指標集的構建. 北京: 北京中醫藥大學, 2021.
21. Qiu R, Zhong C, Han S, et al. Development of a core outcome set for myocardial infarction in clinical trials of traditional Chinese medicine: a study protocol. BMJ Open, 2019, 9(12): e032256.
22. Zhang M, Zhang J, Chua H, et al. Core outcome set for stable angina pectoris in traditional Chinese medicine (COS-SAP-TCM). Acupunct Herb Med, 2021, 1(1): 39-48.
23. 白楊, 宏亞麗, 陳波, 等. 針灸治療粘連性肩關節囊炎臨床研究核心結局指標集的構建方法. 中國針灸, 2023, 43(6): 701-705.
24. 謝倩文, 肖晶旻, 鄧雪儀, 等. 建立中醫藥治療缺血性卒中核心結局指標集的初步研究. 中醫雜志, 2022, 63(3): 220-228.
25. 嵇鑫陳. 中醫藥治療重癥肌無力的臨床研究核心指標集構建研究. 長春: 長春中醫藥大學, 2022.
26. 秦懿囡, 徐天宇, 李澤鑫, 等. 初步構建針刺治療特發性面神經麻痹核心結局指標集. 世界科學技術-中醫藥現代化, 2023, 25(3): 1069-1077.
27. 李心怡, 石兆峰, 胡嘉元, 等. 針刺治療偏頭痛核心結局指標集的建立. 世界科學技術-中醫藥現代化, 2020, 22(1): 7-12.
28. 李凱. 中醫藥治療肺癌核心指標集研究. 天津: 天津中醫藥大學, 2021.
29. Sheng X, Chen C, Ji Z, et al. Development of a core outcome set on traditional Chinese medicine and Western medicine for rheumatic heart disease: a study protocol. BMJ Open, 2022, 12(11): e062497.
30. Zhang T, Li X, Zhao L, et al. Development of a core outcome set in the clinical trials of traditional Chinese medicine for stroke: a study protocol. Front Med (Lausanne), 2022, 9: 753138.
31. Zhang M, Chua HZ, Zhang J, et al. Developing a core outcome set on traditional Chinese medicine (COS-TCM) for chronic heart failure (CHF): a study protocol. BMJ Open, 2021, 11(7): e047148.
32. Dai XY, Zi MJ, Liu CX, et al. Development of a core outcome set in the clinical trials of traditional Chinese medicine for diabetic foot: a study protocol. Front Med (Lausanne), 2022, 9: 1025833.
33. Niu B, Zhang M, Chua HZ, et al. Treatment of chronic pulmonary heart disease with traditional Chinese medicine: a protocol for the development of a core outcome set (COS-TCM-CPHD). Evid Based Complement Alternat Med, 2021, 2021: 5559883.
34. Li G, Han R, Lin M, et al. Developing a core outcome set for clinical trials of Chinese medicine for hyperlipidemia. Front Pharmacol, 2022, 13: 847101.
35. Qiu R, Li M, Zhang X, et al. Development of a core outcome set (COS) and selecting outcome measurement instruments (OMIs) for non-valvular atrial fibrillation in traditional Chinese medicine clinical trials: study protocol. Trials, 2018, 19(1): 541.
36. Liu M, Gao Y, Yuan Y, et al. Sjogren's syndrome in clinical trials of traditional Chinese medicine: protocol for the development of a core outcome set. Trials, 2021, 22(1): 233.
37. Jia M, Lu Y, Liang X, et al. Development of a core outcome set for hypertensive intracerebral hemorrhage in clinical trials of traditional Chinese medicine: a study protocol. Trials, 2022, 23(1): 871.
38. Dodd S, Clarke M, Becker L, et al. A taxonomy has been developed for outcomes in medical research to help improve knowledge discovery. J Clin Epidemiol, 2018, 96: 84-92, 96-84.
39. Basch E, Reeve BB, Mitchell SA, et al. Development of the National Cancer Institute's patient-reported outcomes version of the common terminology criteria for adverse events (PRO-CTCAE). J Natl Cancer Inst, 2014, 106(9): dju244.
40. 張明妍, 張俊華, 張伯禮, 等. 中醫藥臨床試驗核心指標集研制技術規范. 中華中醫藥雜志, 2021, 36(2): 924-928.
41. Williamson PR, Altman DG, Bagley H, et al. The COMET handbook: version 1. 0. Trials, 2017, 18(Suppl 3): 280.
42. 代欣玥. 中醫藥治療糖尿病足臨床研究核心指標集指標域構建研究. 北京: 中國中醫科學院, 2021.
43. 邱瑞瑾. 中醫臨床研究核心指標集的方法構建. 北京: 北京中醫藥大學, 2018.
44. Gargon E, Crew R, Burnside G, et al. Higher number of items associated with significantly lower response rates in COS Delphi surveys. J Clin Epidemiol, 2019, 108: 108-120.
45. Hall DA, Smith H, Heffernan E, et al. Recruiting and retaining participants in e-Delphi surveys for core outcome set development: Evaluating the COMiT'ID study. PLoS One, 2018, 13(7): e0201378.
46. Fish R, MacLennan S, Alkhaffaf B, et al. "Vicarious thinking" was a key driver of score change in Delphi surveys for COS development and is facilitated by feedback of results. J Clin Epidemiol, 2020, 128: 118-129.
47. Brookes ST, Macefield RC, Williamson PR, et al. Three nested randomized controlled trials of peer-only or multiple stakeholder group feedback within Delphi surveys during core outcome and information set development. Trials, 2016, 17(1): 409.
48. Remus A, Smith V, Wuytack F. Methodology in core outcome set (COS) development: the impact of patient interviews and using a 5-point versus a 9-point Delphi rating scale on core outcome selection in a COS development study. BMC Med Res Methodol, 2021, 21(1): 10.
49. Brookes ST, Chalmers KA, Avery KNL, et al. Impact of question order on prioritisation of outcomes in the development of a core outcome set: a randomised controlled trial. Trials, 2018, 19(1): 66.
50. 羅輝, 廖星, 王茜. 中醫證候積分在療效評價中的應用: 基于240項隨機對照試驗的比較研究. 中國中西醫結合雜志, 2015, 35(10): 1261-1266.
51. 陳智慧, 張會永, 裴宇鵬, 等. 基于中醫證候量表探討建立智能化中醫藥臨床決策與療效評價模式的設想. 北京中醫藥大學學報, 2021, 44(3): 221-225.
52. Gorst SL, Prinsen CAC, Salcher-Konrad M, et al. Methods used in the selection of instruments for outcomes included in core outcome sets have improved since the publication of the COSMIN/COMET guideline. J Clin Epidemiol, 2020, 125: 64-75,125-164.
53. Brunton G, Webbe J, Oliver S, et al. Adding value to core outcome set development using multimethod systematic reviews. Res Synth Methods, 2020, 11(2): 248-259.
54. Kirkham JJ, Gorst S, Altman DG, et al. Core Outcome Set-STAndards for Reporting: the COS-STAR statement. PLoS Med, 2016, 13(10): e1002148.
55. Kirkham JJ, Davis K, Altman DG, et al. Core Outcome Set-STAndards for Development: the COS-STAD recommendations. PLoS Med, 2017, 14(11): e1002447.
56. Kirkham JJ, Gorst S, Altman DG, et al. Core Outcome Set-STAndardised Protocol items: the COS-STAP statement. Trials, 2019, 20(1): 116.
57. 邱瑞瑾, 胡嘉元, 李敏, 等. 核心指標集研究方案的標準報告條目解讀及不同核心指標集研究報告指南對中醫藥領域研究的意義. 中國循證醫學雜志, 2019, 19(12): 1492-1497.

Chinese Journal of Evidence-Based Medicine

A scoping review of the core outcome set research in traditional Chinese medicine

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content