Arteriosclerosis in patients with hypertension defined by AHA and classical diagnostic criteria: a cross-sectional study_Chinese Journal of Evidence-Based Medicine

Authors：

SONG Huahua ^1,2 , ZHAO Song ¹ , TANG Jiamin ¹ , JIA Dela ¹ , YANG Haotian ¹ , RU Sitanmujiang ¹ , ZHANG Yi ² ,  WANG Aiping ¹

1. Hengyang Medical College, University of South China, Hengyang 421001, P.R.China;
2. Shanghai Tenth People's Hospital, Shanghai 200072, P.R.China;

Corresponding?author：

WANG Aiping, Email: waiping2011@163.com

Keywords：

Hypertension; Arteriosclerosis; Brachial-ankle pulse wave velocity; Cervical-femoral pulse wave velocity; Cross-sectional study

DOI：

10.7507/1672-2531.202104069

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Objective To evaluate the level of arteriosclerosis in patients with hypertension defined by the American Heart Association (AHA) and classical diagnostic criteria. Methods A total of 3 815 residents were enrolled in 10 communities in north Shanghai. According to the classic diagnostic criteria of hypertension (systolic blood pressure≥140 mmHg and/or diastolic blood pressure≥90 mmHg) and AHA diagnostic criteria (systolic blood pressure≥130 mmHg and/or diastolic blood pressure≥80 mmHg), the population was divided into normal blood pressure group, AHA diagnosis standard hypertension group, and classic methods of diagnosis of hypertension group. The differences in cervical-femoral pulse wave velocity (cf-PWV) and brachial-ankle pulse wave velocity (ba-PWV) among the three groups were compared. SPSS 13.0 software was then used for data analysis.Results Compared with the patients who met the standard criteria, patients who met AHA criteria had lower mean ages (70.2±7.4 vs. 71.4±7.9 year, P<0.001), more history of hypertension (48.8% vs. 72.7%, P<0.001) and lower body mass index (24.1±3.5 vs. 24.7±3.9 kg/m², P<0.001), low-density lipoprotein (3.07±0.92 vs. 3.15±0.97 mmol/L, P=0.033), cf-PWV (8.7±2.7 vs. 9.8±3.0 m/s, P<0.001) and ba-PWV (1 647.7±610.1 vs. 1 797.2±729.7 cm/s, P<0.001). Conclusions The degree of arteriosclerosis of patients who meet AHA standards is between that who meet the standard criteria and the normal population. For these patients, blood pressure should be actively controlled to delay the progression of arteriosclerosis.

Citation： SONG Huahua, ZHAO Song, TANG Jiamin, JIA Dela, YANG Haotian, RU Sitanmujiang, ZHANG Yi, WANG Aiping. Arteriosclerosis in patients with hypertension defined by AHA and classical diagnostic criteria: a cross-sectional study. Chinese Journal of Evidence-Based Medicine, 2021, 21(10): 1122-1125. doi: 10.7507/1672-2531.202104069 Copy

1.	田家瑞, 金石, 金鉉順. 2017年美國ACC/AHA高血壓指南更新解讀. 中國心血管病研究, 2018, 16(10): 885-888.
2.	孫英賢, 李玉明, 蔡軍, 等. 高血壓合并動脈粥樣硬化防治中國專家共識. 中華高血壓雜志, 2020, 28(2): 116-123.
3.	Qi Y, Han X, Zhao D, et al. Long-term cardiovascular risk associated with stage 1 hypertension defined by the 2017 ACC/AHA hypertension guideline. J Am Coll Cardiol, 2018, 72(11): 1201-1210.
4.	Isomaa B, Almgren P, Tuomi T, et al. Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care, 2001, 24(4): 683-689.
5.	Mancia G, Laurent S, Agabiti-Rosei E, et al. Reappraisal of European guidelines on hypertension management: a European society of hypertension task force document. J Hypertens, 2009, 27(11): 2121-2158.
6.	Greenland P, Alpert JS, Beller GA, et al. 2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: executive summary: a report of the American college of cardiology foundation/American heart association task force on Practice Guidelines. Circulation, 2010, 122(25): 2748-2764.
7.	Reference Values for Arterial Stiffness' Collaboration. Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: 'establishing normal and reference values'. Eur Heart J, 2010, 31(19): 2338-2350.
8.	Laurent S, Cockcroft J, Van Bortel L, et al. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur Heart J, 2006, 27(21): 2588-2605.
9.	華琦, 譚靜, 劉東霞, 等. 高血壓病患者頸-股動脈和頸-橈動脈脈搏波速度改變及其影響因素. 中華心血管病雜志, 2005, 33(12): 1088-1091.
10.	馮雪, 劉俊明. 脈搏波傳導速度與高血壓相關性的研究進展. 臨床和實驗醫學雜志, 2013, 12(16): 1340-1341, 1343.

1. 田家瑞, 金石, 金鉉順. 2017年美國ACC/AHA高血壓指南更新解讀. 中國心血管病研究, 2018, 16(10): 885-888.
2. 孫英賢, 李玉明, 蔡軍, 等. 高血壓合并動脈粥樣硬化防治中國專家共識. 中華高血壓雜志, 2020, 28(2): 116-123.
3. Qi Y, Han X, Zhao D, et al. Long-term cardiovascular risk associated with stage 1 hypertension defined by the 2017 ACC/AHA hypertension guideline. J Am Coll Cardiol, 2018, 72(11): 1201-1210.
4. Isomaa B, Almgren P, Tuomi T, et al. Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care, 2001, 24(4): 683-689.
5. Mancia G, Laurent S, Agabiti-Rosei E, et al. Reappraisal of European guidelines on hypertension management: a European society of hypertension task force document. J Hypertens, 2009, 27(11): 2121-2158.
6. Greenland P, Alpert JS, Beller GA, et al. 2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: executive summary: a report of the American college of cardiology foundation/American heart association task force on Practice Guidelines. Circulation, 2010, 122(25): 2748-2764.
7. Reference Values for Arterial Stiffness' Collaboration. Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: 'establishing normal and reference values'. Eur Heart J, 2010, 31(19): 2338-2350.
8. Laurent S, Cockcroft J, Van Bortel L, et al. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur Heart J, 2006, 27(21): 2588-2605.
9. 華琦, 譚靜, 劉東霞, 等. 高血壓病患者頸-股動脈和頸-橈動脈脈搏波速度改變及其影響因素. 中華心血管病雜志, 2005, 33(12): 1088-1091.
10. 馮雪, 劉俊明. 脈搏波傳導速度與高血壓相關性的研究進展. 臨床和實驗醫學雜志, 2013, 12(16): 1340-1341, 1343.

Chinese Journal of Evidence-Based Medicine

Arteriosclerosis in patients with hypertension defined by AHA and classical diagnostic criteria: a cross-sectional study

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