Rating the certainty of evidence from network meta-analysis: an introduction to CINeMA_Chinese Journal of Evidence-Based Medicine

Authors：

WANG Qi ^1,2 ^# , WANG Yunhua ² ^# , LAI Honghao ² , WANG Qi ² , DING Guowu ² , TIAN Jinhui ^3,4 , CHEN Yaolong ^3,4 , YANG Kehu ^3,4 , WU Darong ⁵ , GUO Xinfeng ⁵ , YANG Lihong ⁵ ,  GE Long ^1,2,4

1. Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou 730000, P.R.China;
2. Department of Social Science and Health Management, School of Public Health, Lanzhou University, Lanzhou 730000, P.R.China;
3. Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, P.R.China;
4. Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, P.R.China;
5. The Second Affiliated Hospital of Guangzhou University of Chinese Medicine/Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, P.R.China;

Corresponding?author：

GE Long, Email: gelong2009@163.com

Keywords：

Network meta-analysis; CINeMA; Quality of evidence body

DOI：

10.7507/1672-2531.202002172

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

It is a complex and time-consuming process to rate the certainty (quality) of evidence from network meta-analysis. This paper aims to introduce a web application for rating the certainty of network meta-analysis-the CINeMA. CINeMA is based on GRADE framework and contribution matrix of network meta-analysis, which considers 6 domains including within-study bias, across-studies bias, indirectness, imprecision, heterogeneity, and incoherence.

Citation： WANG Qi, WANG Yunhua, LAI Honghao, WANG Qi, DING Guowu, TIAN Jinhui, CHEN Yaolong, YANG Kehu, WU Darong, GUO Xinfeng, YANG Lihong, GE Long. Rating the certainty of evidence from network meta-analysis: an introduction to CINeMA. Chinese Journal of Evidence-Based Medicine, 2020, 20(9): 1111-1116. doi: 10.7507/1672-2531.202002172 Copy

1.	王琪, 王建成, 潘蓓, 等. 網狀Meta分析證據質量分級: GRADE方法學前沿與進展. 中國循證醫學雜志, 2020, 20(8): 979-985.
2.	Salanti G, Del Giovane C, Chaimani A, <italic>et al</italic>. Evaluating the quality of evidence from a network meta-analysis. PLoS One, 2014, 9(7): e99682.
3.	Institute of Social and Preventive Medicine. CINeMA: confidence in network meta-analysis [Software]. Berne: University of Bern, 2017. Available at: www.cinema.ispm.unibe.ch.
4.	Stern JM, Simes RJ. Publication bias: evidence of delayed publication in a cohort study of clinical research projects. BMJ, 1997, 315(7109): 640-645.
5.	Dickersin K, Chalmers I. Recognizing, investigating and dealing with incomplete and biased reporting of clinical research: from Francis Bacon to the WHO. J R Soc Med, 2011, 104(12): 532-538.
6.	Turner EH, Matthews AM, Linardatos E, <italic>et al</italic>. Selective publication of antidepressant trials and its influence on apparent efficacy. N Engl J Med, 2008, 358(3): 252-260.
7.	王子君, 王小琴, 姚亮, 等. GRADE對健康公平性的考慮. 中國循證醫學雜志, 2018, 18(7): 746-752.
8.	Dias S, Welton NJ, Caldwell DM, <italic>et al</italic>. Checking consistency in mixed treatment comparison meta-analysis. Stat Med, 2010, 29(7-8): 932-944.
9.	Dias S, Welton NJ, Sutton AJ, <italic>et al</italic>. Evidence synthesis for decision making 4: inconsistency in networks of evidence based on randomized controlled trials. Med Decis Making, 2013, 33(5): 641-656.
10.	White IR, Barrett JK, Jackson D, <italic>et al</italic>. Consistency and inconsistency in network meta-analysis: model estimation using multivariate meta-regression. Res Synth Methods, 2012, 3(2): 111-125.
11.	Higgins JP, Jackson D, Barrett JK, <italic>et al</italic>. Consistency and inconsistency in network meta-analysis: concepts and models for multi-arm studies. Res Synth Methods, 2012, 3(2): 98-110.
12.	張慧芳, 馬金沙, 李璐, 等. EGFR-TKIs一線治療晚期非小細胞肺癌的有效性和安全性比較:網狀Meta分析. 中華疾病控制雜志, 2020, 24(2): 210-216.
13.	侯年, 施凱, 李飛, 等. 三種劑量的茚達特羅治療中重度COPD療效和安全性的網狀Meta分析. 中國循證醫學雜志, 2019, 19(8): 924-931.
14.	邱瀟, 楊立川, 李孜. 不同腹膜透析置管方式在發生導管功能障礙比較的網狀Meta分析. 中國循證醫學雜志, 2019, 19(6): 680-686.
15.	Bonner A, Alexander PE, Brignardello-Petersen R, <italic>et al</italic>. Applying GRADE to a network meta-analysis of antidepressants led to more conservative conclusions. J Clin Epidemiol, 2018, 102: 87-98.

1. 王琪, 王建成, 潘蓓, 等. 網狀Meta分析證據質量分級: GRADE方法學前沿與進展. 中國循證醫學雜志, 2020, 20(8): 979-985.
2. Salanti G, Del Giovane C, Chaimani A, <italic>et al</italic>. Evaluating the quality of evidence from a network meta-analysis. PLoS One, 2014, 9(7): e99682.
3. Institute of Social and Preventive Medicine. CINeMA: confidence in network meta-analysis [Software]. Berne: University of Bern, 2017. Available at: www.cinema.ispm.unibe.ch.
4. Stern JM, Simes RJ. Publication bias: evidence of delayed publication in a cohort study of clinical research projects. BMJ, 1997, 315(7109): 640-645.
5. Dickersin K, Chalmers I. Recognizing, investigating and dealing with incomplete and biased reporting of clinical research: from Francis Bacon to the WHO. J R Soc Med, 2011, 104(12): 532-538.
6. Turner EH, Matthews AM, Linardatos E, <italic>et al</italic>. Selective publication of antidepressant trials and its influence on apparent efficacy. N Engl J Med, 2008, 358(3): 252-260.
7. 王子君, 王小琴, 姚亮, 等. GRADE對健康公平性的考慮. 中國循證醫學雜志, 2018, 18(7): 746-752.
8. Dias S, Welton NJ, Caldwell DM, <italic>et al</italic>. Checking consistency in mixed treatment comparison meta-analysis. Stat Med, 2010, 29(7-8): 932-944.
9. Dias S, Welton NJ, Sutton AJ, <italic>et al</italic>. Evidence synthesis for decision making 4: inconsistency in networks of evidence based on randomized controlled trials. Med Decis Making, 2013, 33(5): 641-656.
10. White IR, Barrett JK, Jackson D, <italic>et al</italic>. Consistency and inconsistency in network meta-analysis: model estimation using multivariate meta-regression. Res Synth Methods, 2012, 3(2): 111-125.
11. Higgins JP, Jackson D, Barrett JK, <italic>et al</italic>. Consistency and inconsistency in network meta-analysis: concepts and models for multi-arm studies. Res Synth Methods, 2012, 3(2): 98-110.
12. 張慧芳, 馬金沙, 李璐, 等. EGFR-TKIs一線治療晚期非小細胞肺癌的有效性和安全性比較:網狀Meta分析. 中華疾病控制雜志, 2020, 24(2): 210-216.
13. 侯年, 施凱, 李飛, 等. 三種劑量的茚達特羅治療中重度COPD療效和安全性的網狀Meta分析. 中國循證醫學雜志, 2019, 19(8): 924-931.
14. 邱瀟, 楊立川, 李孜. 不同腹膜透析置管方式在發生導管功能障礙比較的網狀Meta分析. 中國循證醫學雜志, 2019, 19(6): 680-686.
15. Bonner A, Alexander PE, Brignardello-Petersen R, <italic>et al</italic>. Applying GRADE to a network meta-analysis of antidepressants led to more conservative conclusions. J Clin Epidemiol, 2018, 102: 87-98.

Chinese Journal of Evidence-Based Medicine

Rating the certainty of evidence from network meta-analysis: an introduction to CINeMA

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content