The analysis of changes and causes of respiratory diseases prevalence and lung function of school-age children in Chongqing in the past 25 years_Chinese Journal of Evidence-Based Medicine

Authors：

LI Wenyan ¹ ,  LIU Qin ¹ , CHEN Yiwen ¹ , YANG Bo ¹ , HUANG Xin ¹ , LI Yueyue ¹ , ZHANG Junfeng ²

1. School of Public Health and Management, Research Center for Medicine and Social Development, Collaborative Innovation Center of Social Risks Governance in Health, Chongqing Medical University, Chongqing, 400016, P.R.China;
2. Nicholas School of the Environment and Duke Global Health Institute, Duke University, Durham, NC 27708, USA;

Corresponding?author：

LIU Qin, Email: liuqin81622@163.com

Keywords：

Air quality; Nutrition and exercise; Children; Respiratory disease; Pulmonary function; Survey

DOI：

10.7507/1672-2531.201811027

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objectives To investigate the prevalence of respiratory diseases and lung function of school-age children in Chongqing and to compare them with that of children in 25 years ago and to explore the possible causes of this change.Methods According to the air quality data of Chongqing from 1998 to 2016, the annual variation of air quality days and pollutant concentrations were plotted. 2 126 school-age children in two districts of Chongqing were selected by random cluster sampling for questionnaires. 771 children were randomly selected from the children who completed the questionnaire for pulmonary function tests. The results were compared with that of 25 years ago.Results From 1998 to 2016, the number of days with good air quality in Chongqing increased annually, and the concentration of SO₂ decreased significantly. The main air pollution composition changed from SO₂ to PM₁₀ and PM_2.5. The prevalence of bronchitis (P<0.05) was higher than that of 25 years ago. After adjusting for confounding factors by multivariate logistic regression, the OR value of bronchitis in children was 1.667 (P<0.05) compared with 25 years ago. After adjusting for age, sex, height and weight by multiple linear regression, the results showed that the subjects' lung function indexes (FVC, FEV₁, PEF and FEV₃) were lower than that of 25 years ago. In this survey, there were differences in lung function indexes between children with different frequency of eating fruits and dairy products (P<0.05), and those with high frequency consumption were higher than low frequency. In terms of exercise time, subjects exercising ≥1 hour/day had greater FVC and FEV₃ values than those exercising <1 hour/day (P<0.05).Conclusions The overall air quality in Chongqing has improved from 1998 to 2016; The respiratory health of children has decreased when compared with that of 25 years ago. Changes in the composition of air pollutants may endanger children's respiratory health, and fruit and dairy foods and exercise may be protective factors for children's respiratory health.

Citation： LI Wenyan, LIU Qin, CHEN Yiwen, YANG Bo, HUANG Xin, LI Yueyue, ZHANG Junfeng. The analysis of changes and causes of respiratory diseases prevalence and lung function of school-age children in Chongqing in the past 25 years. Chinese Journal of Evidence-Based Medicine, 2019, 19(3): 281-286. doi: 10.7507/1672-2531.201811027 Copy

1.	Salvi S. Health effects of ambient air pollution in children. Paediatr Respir Rev, 2007, 8(4): 275-280.
2.	岳春蘭, 田執梁. 空氣污染與兒童哮喘發病機制的研究進展. 中國兒童保健雜志, 2018, 5(26): 510-517.
3.	唐靖媛, 夏茵茵, 唐旭, 等. 重慶市區不同污染水平地區大氣可吸入顆粒物對兒童呼吸系統影響的抽樣調查. 第三軍醫大學學報, 2015, 37(21): 2195-2198.
4.	唐旭, 黃為, 代華, 等. 重慶市不同大氣污染水平地區學齡兒童呼吸系統癥狀及肺功能的比較. 第三軍醫大學學報, 2017, 34(5): 415-420.
5.	彭中貴, 陳軍, 張毅, 等. 重慶大氣污染與兒童肺功能橫截面研究. 中國環境監測, 2001, 17(7): 98-102.
6.	彭中貴, 張毅, 陳軍, 等. 重慶大氣環境質量與兒童肺功能的前瞻性研究. 中國環境監測, 2001, 17(7): 87-90.
7.	李九彬, 王建力. 2001~2011 年重慶市空氣質量特征分析. 西南大學學報, 2013, 35(9): 145-153.
8.	何勇, 吳亞坤, 陳昌鳴, 等. 2001~2010 年重慶主城區空氣質量變化趨勢. 重慶交通大學學報, 2012, 31(5): 1058-1061.
9.	劉永祺, 李大鵬, 倪長健. 重慶市大氣污染特征及其影響因素分析. 四川環境, 2009, 28(3): 28-32.
10.	李璐. 重慶市 2009~2014 年主城區大氣環境變化分析與對策研究. 無限互聯科技, 2015, 6(11): 85-89.
11.	魏復盛, 胡偉. 中國四城市空氣污染及其對兒童呼吸健康影響的分析. 世界科技研究與發展, 2000, 22(3): 9-11.
12.	李劍東. 長沙市郊區大氣可吸入顆粒物化學組分特性及源解析. 長沙: 中南大學, 2009.
13.	喬莎, 何平, 張愛華. 細顆粒物化學組成及對兒童呼吸系統健康的影響. 世界最新醫學信息文摘, 2016, 16(54): 10-11.
14.	伍燕珍, 張金良, 趙秀閣, 等. 我國大氣污染與兒童呼吸系統疾病和癥狀的關系. 環境與健康雜志, 2009, 26(6): 471-477.
15.	Gilliland FD, Berhane KT, Li YF, et al. Children's lung function and antioxidant vitamin, fruit, juice, and vegetable intake. Am J Epidemiol, 2003, 158(6): 576-584.
16.	Romieu I, Barraza-Villarreal A, Escamilla-Nú?ez C, et al. Dietary intake, lung function and airway inflammation in Mexico city school children exposed to air pollutants. Respir Res, 2009, 10: 122.
17.	郭長江, 楊繼軍. 蔬菜、水果抗氧化作用的研究進展. 中國公共衛生, 2001, 17(1): 87-88.
18.	何啟強, 杜琳, 黃子惠, 等. 膳食營養與學齡兒童呼吸系統健康的相關性研究. 中國預防醫學雜志, 2009, 10(2): 115-119.
19.	劉和亮, 趙金垣. 氧化應激和肺損傷. 中國職業醫學, 2002, 29(5): 49-51.
20.	馬思遠. 我國中小學生體質下降及其社會成因研究. 北京: 北京體育大學, 2012.
21.	Berntsen S, Wisl?ff T, Nafstad P, et al. Lung function increases with increasing level of physical activity in school children. Pediatr Exerc Sci, 2008, 20(4): 402-410.
22.	Ji J, Wang SQ, Liu YJ, et al. Physical activity and lung function growth in a cohort of Chinese school children: A Prospective Study. PLoS One, 2013, 8(6): e66098.
23.	Liu W, Huang C, Hu Y, et al. Associations of gestational and early life exposures to ambient air pollution with childhood respiratory diseases in Shanghai, China: a retrospective cohort study. Environ Int, 2016, (92-93): 284-93.
24.	Deng Q, Lu C, Norb?ck D, et al. Early life exposure to ambient air pollution and childhood asthma in China. Environ Res, 2015, 143(Pt A): 83-92.
25.	龔偉, 婁暢, 王紹華. 北京市延慶區室內環境因素對學齡兒童呼吸系統健康影響的分析. 現代醫學, 2016, 44(3): 277-283.
26.	Svendsen ER, Gonzales M, Commodore A. The role of the indoor environment: residential determinants of allergy, asthma and pulmonary function in children from a US-Mexico border community. Sci Total Environ, 2018, (616-617): 1513-1523.

1. Salvi S. Health effects of ambient air pollution in children. Paediatr Respir Rev, 2007, 8(4): 275-280.
2. 岳春蘭, 田執梁. 空氣污染與兒童哮喘發病機制的研究進展. 中國兒童保健雜志, 2018, 5(26): 510-517.
3. 唐靖媛, 夏茵茵, 唐旭, 等. 重慶市區不同污染水平地區大氣可吸入顆粒物對兒童呼吸系統影響的抽樣調查. 第三軍醫大學學報, 2015, 37(21): 2195-2198.
4. 唐旭, 黃為, 代華, 等. 重慶市不同大氣污染水平地區學齡兒童呼吸系統癥狀及肺功能的比較. 第三軍醫大學學報, 2017, 34(5): 415-420.
5. 彭中貴, 陳軍, 張毅, 等. 重慶大氣污染與兒童肺功能橫截面研究. 中國環境監測, 2001, 17(7): 98-102.
6. 彭中貴, 張毅, 陳軍, 等. 重慶大氣環境質量與兒童肺功能的前瞻性研究. 中國環境監測, 2001, 17(7): 87-90.
7. 李九彬, 王建力. 2001~2011 年重慶市空氣質量特征分析. 西南大學學報, 2013, 35(9): 145-153.
8. 何勇, 吳亞坤, 陳昌鳴, 等. 2001~2010 年重慶主城區空氣質量變化趨勢. 重慶交通大學學報, 2012, 31(5): 1058-1061.
9. 劉永祺, 李大鵬, 倪長健. 重慶市大氣污染特征及其影響因素分析. 四川環境, 2009, 28(3): 28-32.
10. 李璐. 重慶市 2009~2014 年主城區大氣環境變化分析與對策研究. 無限互聯科技, 2015, 6(11): 85-89.
11. 魏復盛, 胡偉. 中國四城市空氣污染及其對兒童呼吸健康影響的分析. 世界科技研究與發展, 2000, 22(3): 9-11.
12. 李劍東. 長沙市郊區大氣可吸入顆粒物化學組分特性及源解析. 長沙: 中南大學, 2009.
13. 喬莎, 何平, 張愛華. 細顆粒物化學組成及對兒童呼吸系統健康的影響. 世界最新醫學信息文摘, 2016, 16(54): 10-11.
14. 伍燕珍, 張金良, 趙秀閣, 等. 我國大氣污染與兒童呼吸系統疾病和癥狀的關系. 環境與健康雜志, 2009, 26(6): 471-477.
15. Gilliland FD, Berhane KT, Li YF, et al. Children's lung function and antioxidant vitamin, fruit, juice, and vegetable intake. Am J Epidemiol, 2003, 158(6): 576-584.
16. Romieu I, Barraza-Villarreal A, Escamilla-Nú?ez C, et al. Dietary intake, lung function and airway inflammation in Mexico city school children exposed to air pollutants. Respir Res, 2009, 10: 122.
17. 郭長江, 楊繼軍. 蔬菜、水果抗氧化作用的研究進展. 中國公共衛生, 2001, 17(1): 87-88.
18. 何啟強, 杜琳, 黃子惠, 等. 膳食營養與學齡兒童呼吸系統健康的相關性研究. 中國預防醫學雜志, 2009, 10(2): 115-119.
19. 劉和亮, 趙金垣. 氧化應激和肺損傷. 中國職業醫學, 2002, 29(5): 49-51.
20. 馬思遠. 我國中小學生體質下降及其社會成因研究. 北京: 北京體育大學, 2012.
21. Berntsen S, Wisl?ff T, Nafstad P, et al. Lung function increases with increasing level of physical activity in school children. Pediatr Exerc Sci, 2008, 20(4): 402-410.
22. Ji J, Wang SQ, Liu YJ, et al. Physical activity and lung function growth in a cohort of Chinese school children: A Prospective Study. PLoS One, 2013, 8(6): e66098.
23. Liu W, Huang C, Hu Y, et al. Associations of gestational and early life exposures to ambient air pollution with childhood respiratory diseases in Shanghai, China: a retrospective cohort study. Environ Int, 2016, (92-93): 284-93.
24. Deng Q, Lu C, Norb?ck D, et al. Early life exposure to ambient air pollution and childhood asthma in China. Environ Res, 2015, 143(Pt A): 83-92.
25. 龔偉, 婁暢, 王紹華. 北京市延慶區室內環境因素對學齡兒童呼吸系統健康影響的分析. 現代醫學, 2016, 44(3): 277-283.
26. Svendsen ER, Gonzales M, Commodore A. The role of the indoor environment: residential determinants of allergy, asthma and pulmonary function in children from a US-Mexico border community. Sci Total Environ, 2018, (616-617): 1513-1523.

Chinese Journal of Evidence-Based Medicine

The analysis of changes and causes of respiratory diseases prevalence and lung function of school-age children in Chongqing in the past 25 years

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content