A Comparative Study of Essential Medicines Lists for Children of WHO, India, South Africa and National Essential Medicine List of China_Chinese Journal of Evidence-Based Medicine

Authors：

 LIUDan ^1,2,3 ^# ,  CHENGJing ⁴ ^# ,  ZHANGLing-li ^1,2 , LIYou-ping ⁵ , ZENGLi-nan ^1,2 , ZHANGChuan ^1,2

1. Department of Pharmacy/Evidence-Based Pharmacy Centre, West China Second University Hospital, Sichuan University, Chengdu 610041, China;
2. Key Laboratory of Birth Defects and Related Diseases of Women and Children(Sichuan University), Ministry of Education, Chengdu 610041, China;
3. West China School of Pharmacy, Sichuan University, Chengdu 610041, China;
4. Sichuan Essential medicines procurement service center, Chengdu 610041, China;
5. Chinese Cochrane Centre and Chinese Evidence-Based Medicine Centre, West China Hospital, Sichuan University, Chengdu 610041, China;

Corresponding?author：

ZHANGLing-li, Email: zhanglingli@scu.edu.cn

Keywords：

Essential medicine list; Essential medicine list for children; Comparative study

DOI：

10.7507/1672-2531.20150067

Video：

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Objective Comparing the worldwide Essential Medicines Lists for Children (EMLcs) and National Essential Medicine List (NEML) of China (2012 edition), to provide evidence for establishing EMLc of China. Method We searched the official websites of WHO and Ministry of Health of some countries to identify published EMLcs. We compared the situation of updating, the number and classification of medicines, and the dosage forms between these EMLcs and NEML of China (2012). Result By August 2013, the WHO, India and South Africa had established EMLc. The number of medicines of NEML of China (2012) ranked first in the four lists. The WHO, India and China classified the medicines by pharmacologic action, while South Africa classified it by anatomical therapeutic chemical (ATC) classification. Except the WHO, India, South Africa and China did not have specific medicines for neonatal care or medicines for diseases of joints. The main administration routes in these four lists were oral administration, injection, and topical application. There were medicine restrictions in EMLcs of WHO and India, while no medicine restrictions in lists of South Africa and China. Conclusion Medicines listed in NEML of China (2012) do not match children's disease burden of China. The applicable dosage forms for children are few and the medicine restrictions are absent for the list. So this list is not suitable for Children.

Citation： LIUDan, CHENGJing, ZHANGLing-li, LIYou-ping, ZENGLi-nan, ZHANGChuan. A Comparative Study of Essential Medicines Lists for Children of WHO, India, South Africa and National Essential Medicine List of China. Chinese Journal of Evidence-Based Medicine, 2015, 15(4): 393-402. doi: 10.7507/1672-2531.20150067 Copy

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Chinese Journal of Evidence-Based Medicine

A Comparative Study of Essential Medicines Lists for Children of WHO, India, South Africa and National Essential Medicine List of China

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